Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$115K - $140K *

Empower your career by driving sales in a dynamic environment. As an Account Manager, leverage your expertise to promote our psychiatry portfolio, navigate market complexities, and build strong relati...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $225K *

Transform healthcare data into actionable insights by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercia...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Accelerate progress at the forefront of enterprise sales, driving complex deals and renewals. Leverage your expertise to build executive relationships and navigate multi-stakeholder environments, ensu...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$149K - $202K *

Transform the HCP launch landscape by leading innovative marketing initiatives for a groundbreaking treatment in Sjögren's disease. Collaborate cross-functionally to engage healthcare professionals an...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in providing strategic legal guidance for commercial agreements, balancing risk management with revenue growth. Collaborate with cross-functional teams to negotiate and optimize contra...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Champion impactful Amazon advertising strategies, driving growth through data-driven insights and hands-on campaign management. Collaborate with clients and internal teams to optimize performance acro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $111K *

Lead the charge in driving successful mortgage-focused projects by coordinating cross-functional teams, applying Agile methodologies, and ensuring alignment with business objectives to promote operati...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Engage with senior stakeholders to enhance R&D efficiency in life sciences. Drive proposals, develop strategies, and ensure quality oversight while building networks to support business development an...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$147K - $195K *

Analyze financial data and lead budgeting processes to drive strategic decision-making. Collaborate with senior leadership to enhance operational efficiency and deliver actionable insights in a dynami...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Lead strategic initiatives by coordinating cross-functional teams to drive major partner launches and product developments, ensuring alignment with executive priorities and measurable outcomes for com...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$112K - $143K *

Engage with key stakeholders to drive revenue growth and expand market share. This role requires strategic networking, relationship management, and a strong field presence to achieve sales targets and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $180K *

Drive the growth of our partner channel by leading recruitment and strategy for ISVs, VARs, and ISOs in the payments landscape. Collaborate across teams to enhance partner relationships and expand rev...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Join a dynamic team to drive sales solutions and foster strong customer relationships within the restaurant sector, enhancing product offerings and customer satisfaction through strategic engagement a...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$163K - $237K *

Lead the charge in shaping advertising agreements for a dynamic legal team. Collaborate across functions to drive growth in our ad tech initiatives while ensuring compliance and efficiency in a fast-p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Shape the future of paid media strategy by advising brands on optimizing campaigns, enhancing performance, and driving growth through innovative advertising solutions and educational initiatives in a...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Media

$73K - $95K *

Join a team that's dedicated to ensuring financial accuracy and compliance. In this pivotal role, you'll manage key accounting processes, support audits, and provide insights that drive informed decis...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$122K - $182K *

Unlock potential by leading enterprise-scale data and AI solutions, modernizing actuarial processes, and driving cloud-native transformations. Collaborate with stakeholders to enhance decision-making...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$144K - $191K *

Unlock potential by leading the Automated Operations capability within Member Services. Oversee AI support experiences, enhance team productivity, and drive continuous improvement to elevate member in...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $250K *

Transform financial services by leading complex banking operations and technology projects. Collaborate with clients to enhance performance, drive innovation, and shape a new practice within a dynamic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $155K *

Champion business development and growth of custom adhesive solutions across North America, focusing on the Bus, Truck, Rail, and Specialty Vehicle markets. Drive customer acquisition and strategic ac...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Drive strategic planning and operational excellence for a dynamic Marketing & Communications team. Own budgeting, resource management, and cross-functional partnerships while leading initiatives that...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join us to manage and enhance our consumer purchase data assets, collaborating with vendors and internal teams to ensure high-quality data acquisition and compliance, driving insights and analytics fo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Advance your career by driving sales growth through consultative selling, relationship building, and strategic prospecting. This role encompasses the full sales cycle, focusing on innovative business...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$135K - $160K *

Help us drive growth as an Enterprise Account Executive, engaging with top-tier clients to tackle fraud challenges using innovative solutions. Collaborate cross-functionally to shape strategies that e...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.