Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Lead cross-functional teams to manage and deliver software implementation projects, enhancing client efficiency and functionality. Collaborate with stakeholders to ensure project success while adherin...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Drive a structured sales strategy for the US region, achieving targets and creating pipelines through outbound prospecting and tailored solutions while engaging senior stakeholders and maintaining CRM...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$119K - $186K *

Manage legal services for indirect sourcing, delivering strategic counsel and project management. Negotiate vendor agreements and ensure compliance while collaborating with stakeholders to support bus...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $215K *

Accelerate product innovation by leading the development of data-driven solutions. Collaborate with cross-functional teams to identify user needs, prototype AI features, and drive business success thr...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$246K - $332K *

Shape the future of health economics and outcomes research by leading strategic initiatives across the nephrology portfolio, ensuring high-quality evidence generation and collaboration with cross-func...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Reimagine operational excellence by integrating data intelligence and insights across multiple business functions. This role enhances strategic decision-making, optimizes workflows, and supports marke...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$112K - $143K *

Champion new business growth by building strategic partnerships and expanding market share within your territory. Drive revenue through effective relationship management and a proactive sales strategy...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $125K *

Join as a hands-on analytics specialist, leveraging Amazon data to drive insights and support decision-making for clients. Collaborate with teams to optimize performance and enhance reporting across v...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$107K - $171K *

Shape the market narrative for AI Agent Identity by leading product marketing initiatives. Own positioning, messaging, and commercial enablement for DNSid, translating complex innovations into compell...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $200K *

Champion operational excellence by leading a high-performing consulting team, driving revenue growth, enhancing customer outcomes, and fostering talent development while executing strategic initiative...

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$203K - $304K *

Champion project success by leading a team of Directors and Managers to drive clinical study strategies, ensuring quality, scope, and budget goals are met while fostering collaboration and continuous...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$203K - $304K *

Manage a team of Directors to drive clinical study projects, ensuring quality, scope, and budget targets are met while fostering collaboration and strategic alignment across global initiatives...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$142K - $210K *

Transform global payroll operations by leading a team to ensure compliance, accuracy, and efficiency across US and international payrolls while managing complex tax and pay issues...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$156K - $195K *

Champion the global eDiscovery Technology practice, leading a diverse team to innovate AI-assisted workflows, ensuring defensibility and quality across jurisdictions while driving growth and operation...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K *

Join a team that's driving revenue growth in the restaurant and hospitality sectors. Leverage your software sales experience to build relationships and engage with senior decision-makers, delivering s...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $106K *

Transform your career by partnering with us to enhance investment operations. As a key player, you'll manage private credit transactions, ensuring accurate accounting and reporting while driving proce...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$143K - $179K *

Champion transformative planning and lead a dynamic team to innovate laboratory solutions while driving excellence and collaboration in the design practice...

United StatesRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$110K - $130K *

Join a team that's redefining event marketing by leading high-impact programs that enhance customer engagement and drive revenue. You'll strategize and execute user summits, trade shows, and field eve...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$120K - $145K *

Join a team that's redefining media pricing and transactions by creating and executing customer-focused product strategies, enhancing user engagement, and navigating a complex media landscape through...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Media

$127K - $149K *

Join a dynamic team to lead strategic transformation initiatives, optimizing business operations and enhancing organizational capabilities. Collaborate across functions to translate strategy into acti...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the architectural vision for scalable Identity Resolution platforms, driving innovation in enterprise applications and data processing. Collaborate with engineering teams to ensure robust, high-p...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $120K *

Advance strategic initiatives by collaborating across teams to launch innovative data tools and insurance programs. Drive project management efforts and contribute to executive presentations that shap...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$246K - $332K *

Drive pediatric development strategy by integrating clinical insights and regulatory commitments across multiple therapeutic areas, ensuring effective execution from candidate transition to post-marke...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.