Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$100K - $120K *

Engage with key customers and partners to drive sales growth across your region. Lead strategic initiatives, develop sales channels, and ensure customer satisfaction while achieving financial objectiv...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Empower cross-functional teams to consolidate payment gateways, leveraging deep USA Payments expertise. Collaborate with stakeholders to analyze requirements, drive migrations, and ensure seamless int...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Drive your career with a strategic sales leadership role focused on enterprise growth in healthcare. Lead complex business development efforts, build executive relationships, and shape solutions that...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Drive growth by building and scaling credit card acquisition channels through innovative affiliate partnerships, targeted paid search, and social programs, while collaborating with cross-functional te...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $200K *

Accelerate progress at the forefront of product innovation, leading a team to drive strategy and customer experience for a key transaction management platform while embedding AI to enhance efficiency...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Transform the landscape of patient care by maximizing sales and awareness of specialized products. Collaborate with healthcare professionals to ensure compliance and enhance patient outcomes while man...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Pioneer innovative finance systems to enhance automation and reporting. Lead the integration of AI and controls in a fast-growing mental health company, collaborating across teams to ensure scalable f...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $100K *

Join a team that's driving growth by acquiring new customers and enhancing revenue through innovative solutions. Manage the full sales cycle while collaborating with cross-functional teams to ensure e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate your career by driving strategic partnerships with top utilities. In this senior role, you'll lead complex enterprise sales, build trusted relationships, and shape innovative solutions, all wh...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$160K - $200K *

Unlock potential by leading global integrated campaigns that drive pipeline and revenue. As a player-coach, you'll manage a high-performing team while executing multi-channel strategies that align wit...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$92K - $110K *

Transform executive support by managing complex calendars, coordinating board meetings, and ensuring seamless communication. Leverage your expertise to anticipate needs and maintain confidentiality in...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$198K - $298K *

Lead the charge in shaping the AMER Revenue Operations strategy, driving operational excellence and predictable outcomes. Collaborate with executive leadership to optimize sales processes and build a...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$120K - $145K *

Drive impactful bank implementations by managing cross-functional teams and aligning stakeholders. Leverage your project management expertise to oversee program execution, enhance client relations, an...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$122K - $187K *

Grow your career by driving strategic sales initiatives within key accounts. Collaborate with C-suite executives to deliver tailored technology solutions, ensuring exceptional customer experiences whi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Lead customer engagement by driving acquisition, relationship management, and sales growth. Collaborate with internal teams to enhance customer satisfaction and product adoption in a dynamic, fast-pac...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $200K *

Innovate the future of customer experience by leading strategic partnerships and driving transformation in AI-driven solutions. Shape commercial strategies that bridge legacy systems with modern, imme...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$122K - $171K *

Unlock potential by driving data-driven insights for Customer Success. Collaborate across teams to enhance customer journeys, optimize growth strategies, and shape analytics foundations that support A...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Unlock new business opportunities by leading strategic development initiatives across key markets. Drive enterprise partnerships through consultative selling, executive networking, and rigorous opport...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$180K - $240K *

Lead strategic business initiatives by building relationships with senior executives to drive revenue growth in life sciences. Develop actionable plans to identify opportunities and enhance market pos...

United StatesRemote

Reposted 3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Empower regulatory excellence by guiding cross-functional teams in compliance and strategy. Leverage deep FDA knowledge to influence promotional materials and ensure adherence to evolving regulations...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate fundraising efforts by cultivating donor relationships and managing special events. Drive strategic initiatives to expand financial support for the foundation while leading a dedicated team to...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Grow strategic partnerships in banking and investing by enhancing existing relationships and acquiring new ones. Collaborate closely with leadership to shape strategies and drive operational success...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Media

$160K - $190K *

Empower your career by leading solution architecture for complex, client-facing programs. Drive technical decisions, mentor teams, and ensure architectural integrity across diverse workstreams in a te...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Information Technology

$135K - $148K *

Drive the successful delivery of complex enterprise projects, ensuring timely execution and high-quality standards. Collaborate cross-functionally to meet client objectives and enhance project managem...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Join us to lead transformational sales in digital operations, driving complex solutions across cybersecurity and manufacturing. Collaborate with stakeholders to unlock value and accelerate customer ou...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.