Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$200K - $250K *

Transform your career by driving new business growth for SMBs through innovative cloud, backup, and disaster recovery solutions. Own your pipeline and strategy while collaborating with a dedicated tea...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$500K+*

Empower your career by developing strategic client relationships and leading a team in tax credit investing. Drive growth through networking and expertise while shaping the company's buyer strategy in...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $120K *

Empower your career by cultivating client relationships and driving sales growth. This role focuses on renewing software subscriptions and upselling products, leveraging strategic insights to enhance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$188K - $230K *

Join a team that's driving innovation in data center materials. You'll manage strategic accounts, lead complex negotiations, and collaborate with global teams to enhance customer relationships and dri...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$160K - $220K *

Shape the future of medical devices by leading regulatory strategies for Class III submissions globally. Manage a dedicated team, ensuring compliance and market access while collaborating cross-functi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a team that's driving enterprise growth in healthcare across the TOLA region. Leverage your strategic selling skills to open new accounts and build executive relationships, transforming patient e...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $140K *

Join a dynamic team as you drive sales in the public safety sector, managing a diverse territory. Leverage AI tools to identify opportunities, close deals, and build lasting relationships with agencie...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $180K *

Drive product strategy and innovation for the Intelligent Gateway product line, enhancing provider engagement and interoperability in healthcare. Collaborate with customers and stakeholders to identif...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$225K - $250K *

Engage with business owners navigating M&A transactions, providing integrated planning and support. Collaborate with deal teams to ensure seamless transitions and optimize after-tax outcomes during cr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$152K - $190K *

Accelerate growth by driving IoT solutions for mid-sized customers, managing complex sales cycles, and fostering relationships with key stakeholders to deliver impactful sensor data solutions...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Grow enterprise SAP relationships by managing key accounts and driving new business. Leverage your expertise to expand client portfolios, develop strategic plans, and ensure client satisfaction while...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Support senior leaders by providing agile administrative assistance, managing complex calendars, coordinating travel, and optimizing processes to enhance operational efficiency across the organization...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Elevate site activation processes by leading strategic planning and execution for clinical trials. Collaborate across teams to ensure timely, high-quality initiation of research sites, driving operati...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead complex project management initiatives across multiple channels in the pharmaceutical advertising sector. Oversee cross-functional teams, ensuring timely delivery within budget while mentoring ju...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $135K *

Lead the charge in developing and managing enterprise proposals and plans, ensuring compliance and quality across submissions. Collaborate with cross-functional teams to enhance win strategies and dri...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Optimize client strategies and drive business growth by leading integrated media planning across channels. Collaborate with cross-functional teams to translate insights into actionable recommendations...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Media

$140K - $175K *

Transform your career by engaging with federal clients, driving enterprise solutions, and building lasting relationships in a dynamic SaaS environment. Leverage your technical expertise to exceed sale...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Engage with us to elevate workplace design through innovative solutions. As a key contributor, you'll lead project documentation, collaborate with teams, and ensure design excellence while managing sc...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$170K - $230K *

Elevate the sales strategy and operations by partnering with leadership to enhance productivity, implement AI solutions, and drive data-driven decision-making. Lead a team to optimize processes and en...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $300K *

Pioneer new sales initiatives by building a pipeline and engaging with diverse industrial clients. Collaborate closely with engineering teams to deliver comprehensive energy solutions while shaping th...

Hiawatha, IARemote

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$150K - $300K *

Transform the energy landscape by building a robust sales pipeline, engaging with diverse clients, and driving innovative solutions in power generation and energy services. Collaborate closely with en...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$82K - $180K *

Transform underwriting strategies by managing excess casualty business, fostering relationships with wholesale partners, and ensuring profitable outcomes while adhering to company guidelines and marke...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$68K - $106K *

Join a team that's driving growth by acquiring new logos and expanding market presence. You'll navigate complex sales cycles, build relationships from scratch, and directly impact company growth while...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $100K *

Unlock insights as you lead analytics for multi-channel marketing initiatives. Collaborate with cross-functional teams to ensure accurate data tracking and reporting, driving performance through actio...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$105K - $115K *

Empower a dynamic sales team to drive revenue growth through strategic partnerships and innovative territory planning. Shape the future of business development by fostering relationships and deliverin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.