Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Sales Development Representative
$85K - $105K *
Join us to drive pipeline growth as a Senior Sales Development Representative. Engage prospects, build relationships, and create qualified opportunities in high-hazard industries, leveraging AI tools...
3 weeks ago
$160K - $200K *
Shape the future of our digital product and engineering landscape by defining a multi-year vision, driving strategic investments, and ensuring a seamless customer experience that aligns with business...
3 weeks ago
Vice President, Regulatory Affairs
$280K - $340K *
Transform regulatory strategy and operations across CMC and clinical activities, leading a high-performing team to ensure compliance and successful product approvals from development through post-appr...
3 weeks ago
$165K - $180K *
Transform your career by driving new customer acquisition in healthcare. Leverage your expertise to build C-suite relationships and lead complex sales processes, contributing to the growth of a dynami...
1 week ago
$100K - $120K *
Partner with us to drive revenue growth and strategic account management across a diverse portfolio. You'll own the full sales cycle, collaborate with cross-functional teams, and build lasting relatio...
2 weeks ago
Area Vice President, RTD & Convenience
$185K - $231K *
Champion a transformative growth agenda for RTD & Convenience, focusing on channel expansion, strategic partnerships, and market leadership to drive profitability and market share while collaborating...
Reposted 1 week ago
$110K - $130K *
Drive new business in Facility Management by identifying prospects, analyzing market needs, and converting leads into clients. Collaborate with marketing and sales teams to deliver tailored solutions...
2 weeks ago
$120K - $145K *
Optimize runtime authorization strategies across diverse segments, driving technical wins and enabling Sales Engineers. Leverage deep IAM and PAM expertise to deliver impactful solutions, ensuring com...
1 week ago
Front Line Sales Leader - Life Sciences - Corporate
$120K - $145K *
Elevate the future of Life Sciences by driving growth and innovation. Lead a high-performing sales team to secure enterprise partnerships, leveraging SaaS and AI solutions to transform customer experi...
6 days ago
$275K - $340K *
Drive growth by leading sales and customer success teams, refining strategies, and optimizing processes. Shape the commercial landscape while mentoring talent and ensuring high-value customer relation...
Today
Director, Business Development
$220K - $260K *
Drive new business initiatives and lead a high-performing team to exceed sales targets. Develop innovative strategies, coach your team, and create a culture of success in a fast-paced, remote environm...
Reposted 3 weeks ago
$95K - $115K *
Lead the charge in expanding business across the Northeast U.S. and Canada by building strategic partnerships, managing client relationships, and driving sales growth through innovative packaging solu...
1 week ago
$150K - $180K *
Join a dynamic team to drive operational excellence across Business Units, ensuring accurate forecasting, insightful reporting, and effective execution. Collaborate closely with GMs to enhance perform...
Reposted 3 weeks ago
$130K - $150K *
Accelerate strategic partner growth through visionary sales leadership, driving revenue and pipeline expansion while cultivating dynamic relationships and actionable growth strategies. Own the partner...
Reposted 6 days ago
Director, Commercial Enablement
$155K - $185K *
Unlock your potential as you design and operationalize strategic processes for commercial success, guiding sales and account management teams to enhance skills and boost effectiveness in a dynamic B2B...
3 weeks ago
Senior Director, Sales Enablement
$175K - $210K *
Transform the sales enablement landscape by leading strategic initiatives that empower teams, enhance training, and drive growth in a dynamic marketplace. Collaborate cross-functionally to ensure ever...
1 week ago
Business Development Director, US Rockies and West Coast
$125K - $150K *
Optimize business growth by identifying new opportunities and building relationships with key stakeholders. Leverage solution-selling expertise to drive enterprise sales and achieve revenue targets wh...
1 week ago
Strategic Sales Director - Public Sector
$130K - $140K *
Accelerate progress at driving growth and expanding market presence through strategic sales planning, client relationship management, and business development in the public sector, ensuring long-term...
1 week ago
Federal Sales Director - Salesforce Services
$150K - $225K *
Accelerate progress at the federal level by driving Salesforce services growth. You'll develop accounts, manage pipeline, and collaborate on solutions involving data, analytics, and AI while ensuring...
3 weeks ago
Regional Sales Manager - Northwest
$80K - $100K *
Unlock potential by driving sales growth in a dynamic territory, cultivating relationships with diverse clients, and leveraging technical expertise to deliver effective packaging solutions that surpas...
Reposted 3 days ago
$125K - $150K *
Lead the charge in transforming public sector consulting by guiding organizations through digital transformation and ERP implementations, while managing high-impact teams and fostering client relation...
2 weeks ago
$80K - $95K *
Accelerate your career by driving revenue growth and managing key accounts in the Western U.S. and Canada. Focus on expanding customer relationships and delivering value through consultative selling w...
6 days ago
$75K - $90K *
Elevate your career by driving growth as an Account Executive, where you'll engage clients, deliver tailored software solutions, and build lasting relationships in the automotive industry. Join us in...
6 days ago
$80K - $95K *
Drive your career forward by cultivating client relationships and exceeding sales goals. As a key player, you'll develop marketing strategies, engage decision-makers, and provide tailored solutions to...
4 days ago
Team Lead, Sales - DSPS - WEST
$125K - $150K *
Join a team that's redefining sales excellence by driving revenue growth and market expansion for innovative SynBio products. Lead a dynamic team, develop strategies, and enhance customer experiences...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.