Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$90K - $110K *

Drive growth by leading sales and technical initiatives in heating and combustion solutions across the Southeast Region, fostering relationships with key clients and internal teams to achieve strategi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Shape the future of homebuilding by leading a small team of engineers to develop innovative solutions. Balance technical ownership and people leadership while driving impactful projects from concept t...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$105K - $123K *

Drive impactful sales enablement strategies to enhance revenue growth and optimize performance within the Institutional Trust Division, collaborating with stakeholders to foster business development a...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Manage a team of engagement managers to enhance operational effectiveness, drive project execution, and implement innovative solutions. Oversee financial performance and resource allocation while fost...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$152K - $203K *

Elevate client partnerships by uncovering growth opportunities and building trusted executive relationships. Drive strategic conversations that connect client needs to innovative solutions, fostering...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$118K - $196K *

Elevate your career as a key member of an agile software engineering team, driving the design and development of scalable applications. Collaborate across all stages of the software lifecycle to deliv...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Empower your career by cultivating client relationships and driving sales growth. This role focuses on renewing software subscriptions and upselling products, leveraging strategic insights to enhance...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$141K - $234K *

Lead the charge in healthcare performance improvement by overseeing project delivery, managing client relationships, and mentoring a team of Advisory consultants to ensure successful, high-quality out...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $139K *

Lead the charge in building vibrant customer communities and executing an impactful Employee Advocacy program. Collaborate cross-functionally to enhance engagement, share insights, and ensure a unifie...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Shape the future of project management by leading software implementations, enhancing efficiency, and collaborating with diverse teams. Drive success through strategic planning and effective communica...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Champion integrated marketing strategies to drive growth, enhance brand awareness, and support sales initiatives. Lead cross-functional teams in executing customer-centric programs that generate deman...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$225K - $250K *

Drive growth and strategic direction in Education Communications by leading product portfolios, enhancing customer engagement, and ensuring financial performance aligns with market needs and opportuni...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$125K - $141K *

Lead the product direction for membership operations, balancing customer needs and enterprise requirements. Collaborate with teams to enhance workflows, improve operational outcomes, and ensure a seam...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $130K *

Champion strategic growth by collaborating with practice groups to enhance business development initiatives, drive revenue, and support client engagement. Play a key role in shaping marketing strategi...

Reposted yesterday

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $145K *

Lead the design and implementation of B2B revenue accounting processes, ensuring efficient contract-to-cash operations while collaborating with cross-functional teams to drive growth and reduce manual...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $230K *

Lead the charge in driving growth and performance across multiple channels, optimizing customer journeys and aligning cross-functional teams to achieve measurable outcomes in MRR and product expansion...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$154K - $220K *

Join a team that's driving innovation in On-Demand Mobility and Fleet Technology. You'll cultivate strategic customer relationships, identify growth opportunities, and leverage HERE's advanced locatio...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$280K - $325K *

Join a dynamic team to drive sales growth in the Ohio Valley, managing the full sales cycle for innovative cybersecurity solutions. Leverage your expertise to build relationships and exceed quotas whi...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Transform the sales process by providing expert technical support and product demonstrations. Collaborate with internal teams to address customer needs and enhance training, ensuring a seamless experi...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$135K - $151K *

Drive product strategy and execution for Patient Experience solutions, enhancing healthcare practices' connection with patients. Lead cross-functional teams, leverage AI, and optimize workflows to imp...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Accelerate growth in Biologics by leading global business development efforts, driving new market creation, and forging strategic partnerships. Collaborate across teams to implement data-driven strate...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Unlock your potential by driving customer success and strategic growth. Collaborate with cross-functional teams to enhance customer outcomes, mitigate risks, and expand enterprise accounts, ensuring l...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $155K *

Elevate product initiatives within the casino vertical by driving discovery, stakeholder engagement, and roadmap management. Collaborate with cross-functional teams to enhance player experience and en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$110K - $155K *

Lead and manage valuation consulting engagements, delivering high-quality advisory services while developing team members and strengthening client relationships to drive strategic growth in the Valuat...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Legal & Accounting

$56K - $111K *

Drive success by cultivating strong relationships with clients to enhance satisfaction, retention, and sales growth. Collaborate with teams to deliver tailored solutions and insights, ensuring a seaml...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.