Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$95K - $110K *

Lead the charge in managing hospital partnerships, ensuring operational excellence, team development, and client satisfaction while driving growth and compliance in a fast-paced healthcare environment...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $230K *

Lead the charge in developing enterprise pricing strategies that optimize profitability and drive growth across diverse service sectors, ensuring alignment with market conditions and client needs whil...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$120K - $140K *

Lead the charge in delivering innovative healthcare solutions by engaging with clients, understanding their needs, and providing technical guidance throughout the sales process to drive successful out...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$160K - $190K *

Join us as a strategic advisor, providing legal counsel on commercial contracts, AI products, and technology licensing. Collaborate with cross-functional teams to drive proactive solutions and support...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $120K *

Unlock potential by leading day-to-day accounting operations, ensuring accurate financial reporting, and driving process improvements in a dynamic e-commerce environment. Collaborate across teams to e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $185K *

Elevate executive and client experiences by designing luxury hospitality programs across a national portfolio, ensuring exceptional service standards and memorable interactions in corporate environmen...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$120K - $155K *

Join a team that's dedicated to nurturing and expanding client relationships in the Major Market sector. Drive revenue growth through upselling and cross-selling while ensuring long-term satisfaction...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Business Services

$125K - $190K *

Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $220K *

Strategize and oversee the development of a cohesive IT and cybersecurity strategy to support a high-growth B2B software organization, ensuring alignment with business goals and compliance standards w...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$82K - $108K *

Accelerate growth by identifying and securing new business opportunities in agriculture. Leverage industry expertise and consultative selling to engage decision-makers, build pipelines, and drive cust...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Shape the future of branch operations by leading a dynamic team, driving financial success, and fostering strong customer relationships while ensuring safety and quality in project execution...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $230K *

Unlock potential by driving strategic sales in the Life Sciences sector. Engage with key stakeholders, shape IT solutions, and achieve ambitious growth targets while leveraging your extensive network...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $85K *

Drive your career forward by managing operations that boost sales, profitability, and customer satisfaction. Lead a dynamic team, oversee financial management, and develop strategic plans to enhance m...

5 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$88K - $105K *

Lead and manage complex multidisciplinary design projects, ensuring high-quality execution and fostering strong client relationships. Collaborate with diverse teams to deliver on time and within budge...

4 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$175K - $210K *

Lead the charge in shaping post-quantum security solutions. Drive partnerships, develop the semiconductor ecosystem, and empower the commercial team with technical insights to create demand and establ...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$90K - $110K *

Grow your career with a dynamic role focused on sales success and account management. Drive profitable solutions in the retail sector while fostering long-lasting customer relationships and delivering...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $128K *

Lead and optimize sales teams to drive revenue growth and enhance client relationships. Collaborate with cross-functional teams to implement strategic plans, ensuring customer success and market expan...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$149K - $205K *

Elevate innovation at the forefront of foodtech, agritech, and infrastructure. Lead strategic initiatives, build ecosystems, and drive new ventures to shape the future landscape of Mitsubishi Electric...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $162K *

Join us to develop strategic business plans and conduct effective sales presentations while achieving goals in the pharmaceutical territory. Build relationships, influence key stakeholders, and drive...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead strategic banking initiatives by leveraging your enterprise sales expertise to build relationships and drive new business within Tier 1 global banks, shaping our go-to-market strategy and establi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$241K - $295K *

Drive drug substance commercial manufacturing excellence by leading technology transfer, operational oversight, and continuous improvement initiatives across multiple CDMO sites, ensuring alignment wi...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$152K - $190K *

Join a team that's transforming industries through IoT solutions, driving impactful sales from prospecting to closing. Engage with executives, build lasting relationships, and thrive in a high-perform...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $250K *

Champion the growth of Spine product sales across the Midwest and North Central regions. Lead training initiatives, manage agency performance, and drive strategic sales efforts to enhance market prese...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Empower your marketing expertise to drive strategy, revenue, and brand positioning across multiple segments. Lead a dynamic team, collaborate with executives, and shape customer advocacy initiatives t...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$130K - $176K *

Empower a dynamic team by leading supply chain strategies, enhancing material availability, and optimizing inventory management across multiple sites to meet business goals and customer commitments in...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.