Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Director, Global People Operations
$232K - $290K *
Shape the future of global People Operations by leading innovative HR service delivery, enhancing employee experiences, and driving operational excellence in a rapidly scaling biopharmaceutical enviro...
3 weeks ago
$88K - $105K *
Drive project success by effectively managing timelines, budgets, and resources. Collaborate with teams to ensure construction objectives are met while fostering communication with clients and stakeho...
3 weeks ago
$110K - $130K *
Analyze technical sales opportunities from discovery to close, leveraging AI tools and client data to drive business cases. Collaborate with cross-functional teams to ensure seamless implementation an...
1 week ago
Account Executive - Compliance Sales
$88K - $150K *
Shape the future of cybersecurity by driving growth in strategic accounts. Leverage your expertise to build executive relationships, navigate complex sales cycles, and expand our compliance audit and...
2 weeks ago
$92K - $166K *
Join a team that's dedicated to managing waterfront modernization and maintenance for naval systems. Oversee diverse teams, coordinate complex schedules, and ensure compliance with technical and safet...
Today
Strategic Account Director, Key Accounts
$150K - $180K *
Join a team that's driving enterprise growth by managing key accounts, expanding relationships, and executing strategic plans. Leverage your expertise to enhance customer value and influence major org...
2 weeks ago
Digital Delivery Manager - Energy Advisory | 1898 & Co
$110K - $130K *
Advance your career by leading digital delivery and innovation in Energy Advisory. Collaborate across teams to connect business needs with digital solutions, ensuring scalable and sustainable project...
1 week ago
$125K - $150K *
Lead the enterprise project controls function, enhancing financial performance and establishing best practices across multiple firms. Collaborate with teams to ensure project health, profitability, an...
Reposted today
$130K - $160K *
Champion market access strategies for innovative healthcare products, driving payer engagement and reimbursement pathways. Lead cross-functional initiatives to enhance adoption and streamline operatio...
3 weeks ago
Regional Director of Specialty Operations
$110K - $130K *
Elevate specialty hospital operations by providing strategic leadership, enhancing workflows, and driving financial performance across multiple facilities. Collaborate with veterinary leaders to optim...
1 week ago
Director of Product Management, Applications
$150K - $180K *
Lead the charge in shaping product strategy and execution for a key applications portfolio, driving innovation and growth through AI integration while mentoring a high-performing team in a dynamic hea...
1 week ago
$90K - $150K *
Join a dynamic team to build and manage strategic partnerships in the public safety sector. Drive partner engagement, enhance sales enablement, and contribute to pipeline growth while collaborating cr...
1 week ago
Business Development Lead (South Central Region)
$115K - $140K *
Unlock potential by driving foodservice sales growth across the South Central Region. Build strategic customer relationships, develop new business opportunities, and collaborate with cross-functional...
Today
Sr. Manager - Procurement Services
$140K - $180K *
Accelerate procurement excellence by leading high-impact customer engagements, driving strategic initiatives, and fostering a culture of continuous improvement within a dynamic team environment...
3 weeks ago
Senior Account Executive, Public Sector
$130K - $150K *
Lead strategic sales initiatives within the public sector, driving new business and expanding existing accounts. Manage complex SaaS deals, build strong relationships, and deliver tailored solutions t...
3 weeks ago
$140K - $185K *
Collaborate with cross-functional teams to drive product strategy, manage roadmaps, and enhance customer experiences. Lead product initiatives, ensuring alignment with business goals while mentoring j...
3 weeks ago
Senior Customer Advocacy Specialist
$92K - $139K *
Elevate your career by leading customer advocacy initiatives that drive engagement and impact. Collaborate cross-functionally to enhance customer relationships and leverage insights for program growth...
2 weeks ago
$340K - $445K *
Lead the global communications strategy to enhance brand visibility and thought leadership. Oversee internal and external communications, manage crisis situations, and mentor a high-performing team to...
4 days ago
Territory Sales Manager - Specialty (Portland, OR)
$113K - $142K *
Shape the future of healthcare by driving sales growth and building strong relationships. Leverage your clinical expertise and market insights to exceed objectives and enhance market share in a dynami...
3 weeks ago
$95K - $115K *
Lead the charge in optimizing pricing processes, ensuring alignment across teams to drive strategic growth and enhance profitability while maintaining compliance and governance in pricing operations...
Reposted 2 weeks ago
Life Sciences Commercial, Management Consulting Principal Director
$150K - $375K *
Join a team that's transforming life sciences through strategic commercial leadership. Drive large-scale engagements, foster client relationships, and deliver innovative solutions that enhance operati...
2 weeks ago
Vice President, Value Partnerships DX
$207K - $284K *
Elevate strategic partnerships in the healthcare diagnostics sector, driving innovative solutions and collaboration across teams. Lead high-impact initiatives that align customer needs with Siemens He...
3 weeks ago
Senior Director, Client Advisory and Insights
$150K *
Shape the future of client success by leveraging insights and data to enhance program impact. Collaborate with leaders in law firms and professional services to drive engagement and talent development...
Reposted 2 days ago
$110K - $130K *
Accelerate progress at the forefront of enterprise sales, driving growth through strategic relationship building and complex deal management. Own the sales lifecycle while collaborating with teams to...
Today
Senior Managing Counsel-Pharmacy Network Operations
$197K - $328K *
Shape the future of pharmacy network operations by leading a team of attorneys, providing strategic legal counsel on regulatory, operational, and transactional matters within the PBM landscape, while...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.