Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Strategic Account Manager - West Coast
$125K - $150K *
Champion growth by developing new enterprise accounts in Healthcare and Financial Services. Leverage strategic relationships and innovative solutions to drive business value and expand market presence...
Reposted today
PBS Engineering Managing Director
$209K - $349K *
Drive engineering excellence by leading modernization and integration efforts across technology platforms, ensuring seamless client transitions and operational stability while aligning with strategic...
2 weeks ago
Pharmaceutical District Sales Manager
$110K - $130K *
Lead the charge in developing high-performing sales teams while driving growth and accountability. This role focuses on hiring, coaching, and strategic planning to exceed corporate objectives in the p...
4 days ago
Senior Manager, Solutions Engineering - State, Local, Educational (SLED) Top 1200
$172K - $215K *
Lead and develop a national Solutions Engineering team, driving technical wins and ensuring effective deployment of drone technology in public safety. Collaborate with sales and product teams to enhan...
4 weeks ago
$118K - $157K *
Transform manufacturing operations by leading teams to enhance safety, productivity, and cost-effectiveness while driving continuous improvement and compliance with regulations. Join a team that's com...
1 week ago
$110K - $130K *
Transform organizational communication by building editorial standards, streamlining workflows, and enhancing writing quality across diverse teams. Collaborate with leaders to ensure clarity, purpose...
Reposted 1 week ago
Strategic Account Executive, Healthcare - West Coast
$125K - $150K *
Unlock potential by driving enterprise growth in the TOLA region through strategic sales. Engage with senior healthcare executives to transform patient experiences using AI, while managing complex sal...
Today
Regional Sales Manager - Climate Control
$108K - $149K *
Inspire growth by leading a regional sales team to achieve goals, enhancing customer experiences, and developing effective training programs while driving profitable revenue through strategic leadersh...
Reposted today
Director, Enterprise Portfolio Management
$150K - $195K *
Drive change management initiatives that enhance employee engagement and operational efficiency. Collaborate across teams to ensure successful adoption of technology and policy changes, while providin...
Reposted today
$150K - $180K *
Join a team that's redefining renewable energy asset management. Lead the oversight of a diverse portfolio, ensuring optimal performance, compliance, and financial returns while managing third-party o...
3 weeks ago
Regional Director, Enterprise Sales
$185K - $210K *
Lead enterprise sales strategy across the Eastern US, driving revenue growth and fostering executive relationships while coaching a high-performing team. Collaborate cross-functionally to optimize sal...
Reposted 4 days ago
$110K - $130K *
Join a dynamic team to lead proposal and security response efforts, driving innovation and quality. Manage a skilled group, streamline processes, and enhance collaboration across functions to achieve...
2 weeks ago
$100K - $120K *
Accelerate progress at the forefront of real estate investment, overseeing renovation and operational excellence across multiple markets. Drive financial performance, solve complex challenges, and lea...
3 weeks ago
Structured Settlement Sales Consultant
$80K - $95K *
Engage with personal injury attorneys to build trust and drive settlement planning referrals. Leverage your expertise in financial planning and relationship management to generate new business opportu...
1 week ago
Structured Settlement Sales Consultant
$80K - $95K *
Join a team that's dedicated to building strong relationships with personal injury attorneys. Leverage your expertise in settlement planning and wealth management to drive business growth and support...
1 week ago
$200K - $232K *
Unlock potential by leading legal reviews for promotional and medical materials. Collaborate across teams to ensure compliance and provide practical guidance in a fast-paced environment, supporting pr...
2 weeks ago
Senior Manager, Medicare Product & Market Intelligence
$129K - $168K *
Support the strategic development and execution of Medicare growth initiatives, guiding teams in product strategy, competitive analysis, and bid management to drive profitable growth and successful ma...
Reposted today
Founding Senior Account Executive
$110K - $130K *
Drive Beam's growth by securing partnerships and expanding market presence. Lead the sales cycle for Beam Notes, engaging key sectors and refining strategies to enhance product-market fit in the US. Y...
1 week ago
Enterprise Account Executive, Florida
$290K - $305K *
Pioneer enterprise sales in Florida, driving value-based solutions for large organizations. Collaborate with cross-functional teams to exceed targets, utilizing strategic partnerships to enhance growt...
Reposted 2 weeks ago
$100K - $120K *
Engage your leadership skills in a dynamic sales role, mentoring new team members while managing your own client relationships. Drive success through proven sales strategies and personalized insurance...
Reposted 1 week ago
$72K - $116K *
Engage in financial analysis and reporting, developing forecasts and insights. Collaborate across departments to enhance business outcomes and present findings to management, driving strategic decisio...
Reposted 2 weeks ago
Specialty Development Executive - West Territory
$140K - $180K *
Advance healthcare by driving product adoption and education in colorectal cancer screening across a key geographic territory. Collaborate with healthcare providers to enhance market penetration and e...
Reposted 3 weeks ago
Senior Administrator, Systems Management
$110K - $130K *
Transform endpoint management by designing and deploying solutions across a vast device estate. Collaborate with cross-functional teams to ensure security, compliance, and reliability while leveraging...
3 weeks ago
Divisional Vice President (Northeast)
$200K - $240K *
Manage a team of external sales professionals to drive the sale of qualified retirement plans across various financial channels, ensuring productivity and strategic growth within the assigned territor...
4 weeks ago
$110K - $130K *
Advance product development by collaborating with cross-functional teams to manage lifecycles, ensure compliance, and drive technology innovations for enhanced customer experience and market competiti...
Reposted 4 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.