Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$127K - $187K *
Join a team that's driving growth by building strategic partnerships with K-12 education leaders. This role focuses on managing a regional portfolio, executing sales strategies, and presenting innovat...
1 week ago
$100K - $120K *
Drive client success by enhancing revenue cycle performance and fostering strategic relationships with enterprise clients. Leverage expertise to implement solutions, manage risks, and ensure measurabl...
Reposted yesterday
Business Development Manager - Civil Specifications (Southwest USA)
$91K - $155K *
Drive market growth by establishing trench drain solutions as design standards among engineers. Build relationships, promote products, and influence specifications to enhance sales and market presence...
4 weeks ago
$100K - $110K *
Elevate the impact of early childhood development by managing and expanding the HELP product suite. Drive customer relationships, account growth, and new business development while supporting practiti...
1 week ago
$175K - $292K *
Lead the charge in driving demand and revenue growth through innovative marketing strategies, integrated campaigns, and collaboration with cross-functional teams to enhance buyer journeys and optimize...
Reposted 4 days ago
$89K - $120K *
Transform your sales career by driving revenue growth through strategic partnerships. Manage the full sales cycle, collaborate with teams, and leverage your expertise in cloud computing to attract and...
1 week ago
$110K - $130K *
Champion strategic growth by managing key accounts, fostering relationships, and driving sales initiatives. Collaborate with leadership to meet customer needs and exceed performance objectives while r...
Reposted 2 weeks ago
Director, GPO Strategic Accounts Specialty Pharmacy/Payer Account Management
$142K - $177K *
Drive strategic growth by managing high-impact relationships with health systems and specialty pharmacies. Lead account management, enhance client satisfaction, and identify opportunities for value ex...
Yesterday
Small Business Account Executive II
$142K - $200K *
Unlock your potential by owning the full sales cycle for high-growth merchants. Engage with executive decision-makers, create tailored solutions, and drive new partnerships while collaborating across...
3 weeks ago
$100K - $120K *
Help us drive growth by identifying and closing automation opportunities. Collaborate with technical teams to deliver tailored solutions, build lasting customer relationships, and exceed sales targets...
2 weeks ago
Project Executive - Industrial
$150K - $180K *
Lead the charge in delivering large-scale industrial projects, ensuring operational excellence and client satisfaction while developing high-performing teams and driving strategic growth across missio...
4 weeks ago
$185K - $225K *
Champion exceptional member experiences by leading operations, developing talent, and ensuring financial success in a dynamic private club environment. Drive collaboration and accountability while enh...
Yesterday
Sr. Manager, Finance & Value Realization
$132K - $166K *
Unlock financial insights at a strategic level, driving value realization and governance for transformation investments. Collaborate across functions to enhance performance, support decision-making, a...
3 weeks ago
Regional Sales Consultant - EST, CST
$80K - $95K *
Transform healthcare engagement by building relationships with HCPs through effective communication and digital interactions, promoting client products to maximize sales potential and achieve program...
2 weeks ago
Program Manager, Commercial Solutions
$135K - $160K *
Innovate and manage large-scale commercial programs, driving cross-functional alignment and revenue growth. Lead end-to-end program development, ensuring operational excellence and strategic execution...
1 week ago
Vice President Finance - Jefferson
$150K - $180K *
Lead financial operations in a healthcare setting, overseeing accounting, payroll, budgeting, and regulatory reporting. Collaborate with teams to enhance decision support and ensure compliance while d...
2 weeks ago
Head of Consumer Segment, NAM (US)
$150K - $180K *
Reimagine the consumer landscape by leading strategy and performance for a dynamic business across North America. Drive growth, enhance customer experience, and influence global teams to deliver excep...
4 days ago
Key Account Leader, Mid Cities West
$110K - $140K *
Transform public safety by leading sales for drone technology in mid-sized agencies. Own your territory, drive full-cycle deals, and build trust with key stakeholders to secure funding and deployment...
4 days ago
$115K *
Transform your career by driving net-new logo sales in the mid-market space. Leverage your HRMS/Payroll expertise to exceed quotas and build lasting client relationships while benefiting from exceptio...
2 weeks ago
$82K - $103K *
Champion sales initiatives by directing activities in a defined area, fostering relationships with key stakeholders, and executing innovative marketing strategies to drive growth in corporate retireme...
6 days ago
Business Development Manager-Healthcare & Life Science
$110K - $140K *
Elevate our healthcare growth strategy by managing pipeline generation, leveraging AI tools, and driving marketing initiatives. This role demands autonomy and innovation to shape business operations a...
3 weeks ago
Business Development Leader - Springfield MO
$125K *
Empower growth by driving sales in hygienic fluid handling across Southwest MO & NW Arkansas. Build lasting relationships with food, dairy, beverage, and pharmaceutical manufacturers while leveraging...
1 week ago
Director, Advanced Cooling Category Management, NA
$190K - $200K *
Drive global mechanical category strategy for advanced thermal management systems, ensuring optimal cost, quality, and reliability across a diverse supplier ecosystem while supporting scalable data ce...
Reposted 2 weeks ago
Executive Director, Enterprise Regional Enablement
$126K - $188K *
Accelerate progress at the forefront of operational risk enablement, leading regional teams to implement enterprise standards, build capabilities, and foster relationships across diverse stakeholders...
4 days ago
Director, Product Strategy & Monetization
$185K - $255K *
Transform the financial engine of R&D by leading revenue strategies, pricing, and cost management. Collaborate with senior leaders to align short-term goals with long-term product vision, while buildi...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.