Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$160K - $200K *
Shape the future of Investor Relations by developing and executing impactful strategies to enhance communication with the investment community, drive corporate strategy alignment, and maximize shareho...
Reposted 1 week ago
$110K - $130K *
Champion growth in the retail sector by driving account development and sales. Leverage strong customer relationships to enhance satisfaction and profitability while effectively managing your sales pi...
Reposted 2 weeks ago
Senior Director, Franchise Commercial Execution
$198K - $230K *
Join a team that's shaping the future of commercial execution by integrating strategies across channels and customers to drive sustainable growth and measurable outcomes in a dynamic, collaborative en...
4 days ago
Senior Manager, Trust Services
$110K - $130K *
Unlock potential by leading a global team in Trust Services, enhancing client relationships, and driving operational excellence. Shape the future of AI-powered security solutions while ensuring top-ti...
1 week ago
Salesforce Account Executive - SLED
$150K - $185K *
Lead the charge in driving growth through strategic Salesforce partnerships, focusing on SLED organizations. Build relationships, manage complex sales cycles, and position solutions that transform pub...
1 week ago
Regional Vice President, Strategic Solution Engineering (Central)
$192K - $215K *
Drive strategic growth by leading a high-performing team to enhance customer success and revenue in key accounts, aligning regional strategies with corporate goals while fostering strong relationships...
4 weeks ago
Restaurant and Franchise - Managing Director
$121K - $262K *
Join a dynamic team to drive client relationships and deliver tailored financial solutions. Lead business development strategies, oversee credit underwriting, and foster collaboration across departmen...
1 week ago
Account Director, Growth Mid-Market
$110K - $124K *
Shape the future of client partnerships by leading strategic growth initiatives, enhancing relationships, and driving revenue through innovative AI tools and workflows. Collaborate with teams to optim...
2 weeks ago
$146K - $189K *
Partner with us to enhance our community health provider network. Leverage your expertise in provider relations and network management to drive growth, improve access to care, and support our mission...
3 weeks ago
Business Development Manager - West Coast
$100K - $120K *
Drive growth by developing strategic partnerships in the travel industry. Leverage your expertise to identify opportunities, negotiate agreements, and support travel advisors and agencies in maximizin...
1 week ago
$120K - $150K *
Transform your career by owning full-cycle sales for top-tier accounts. Drive pipeline growth, engage complex stakeholders, and close high-value deals while collaborating with a dedicated team in a dy...
Reposted 3 weeks ago
$175K - $185K *
Pioneer innovative analytics and AI solutions in healthcare. Drive product strategy and collaborate with cross-functional teams to transform complex data into actionable insights and measurable value...
Reposted 1 week ago
Group Account Director (Medical Affairs)
$165K - $185K *
Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...
Reposted 2 weeks ago
Myna Account Executive, Healthcare and Dental
$100K - $120K *
Join a team that's transforming healthcare with AI solutions. Drive full-cycle sales, engage decision-makers, and exceed quotas while improving patient access and operational efficiency in dental and...
Today
Myna Account Executive, Healthcare and Dental
$100K - $120K *
Join a dynamic sales team to drive AI-powered solutions in healthcare. Engage with decision-makers, uncover challenges, and demonstrate Myna's value to enhance patient access and streamline operations...
Today
Account Executive, Platform - FSI
$130K - $195K *
Drive enterprise sales success by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology solutions to business outcomes. Leverage your expertise in cloud architecture and AI t...
1 week ago
$110K - $130K *
Elevate enterprise AI initiatives by partnering with clients to drive strategic solutions. Leverage your expertise to engage senior leaders, design impactful demos, and accelerate deal cycles, ensurin...
3 days ago
$111K - $150K *
Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...
4 weeks ago
Commercial Account Executive - Mid Market (Remote)
$80K - $95K *
Grow your career by driving strategic account management and revenue expansion for mid-market clients. Engage with key decision-makers, develop tailored solutions, and lead negotiations to foster long...
5 days ago
$125K - $145K *
Lead the charge in managing key client relationships within Pharmacy Benefit Management, ensuring high-quality service delivery and client satisfaction through effective communication and consultative...
Yesterday
$95K - $115K *
Elevate financial operations by overseeing budgeting, forecasting, and reporting. Collaborate with leadership to drive strategic insights and strengthen compliance while mentoring a dynamic finance te...
2 weeks ago
Government Sales Director - Software
$120K - $170K *
Join a team that's driving growth in government sales by leading strategic initiatives with the FAA. This role focuses on expanding business opportunities and fostering relationships across complex av...
1 week ago
Director, Franchise Operations - North
$145K - $169K *
Optimize strategic partnerships and drive performance across the Coca-Cola portfolio in the North Zone. Lead execution excellence, align priorities, and foster growth through collaboration with bottle...
4 days ago
$100K - $120K *
Drive business growth by assessing market opportunities, developing strategies, and delivering compelling presentations. Collaborate with teams to align marketing efforts and support client proposals...
6 days ago
Managing Director, Investor Advisory
$160K - $200K *
Lead the translation of investment strategies into tailored client policies, ensuring alignment with firm philosophy. Drive portfolio reviews, client communication, and advisor training while collabor...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.