Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$160K - $200K *

Shape the future of Investor Relations by developing and executing impactful strategies to enhance communication with the investment community, drive corporate strategy alignment, and maximize shareho...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Champion growth in the retail sector by driving account development and sales. Leverage strong customer relationships to enhance satisfaction and profitability while effectively managing your sales pi...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$198K - $230K *

Join a team that's shaping the future of commercial execution by integrating strategies across channels and customers to drive sustainable growth and measurable outcomes in a dynamic, collaborative en...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $130K *

Unlock potential by leading a global team in Trust Services, enhancing client relationships, and driving operational excellence. Shape the future of AI-powered security solutions while ensuring top-ti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $185K *

Lead the charge in driving growth through strategic Salesforce partnerships, focusing on SLED organizations. Build relationships, manage complex sales cycles, and position solutions that transform pub...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$192K - $215K *

Drive strategic growth by leading a high-performing team to enhance customer success and revenue in key accounts, aligning regional strategies with corporate goals while fostering strong relationships...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$121K - $262K *

Join a dynamic team to drive client relationships and deliver tailored financial solutions. Lead business development strategies, oversee credit underwriting, and foster collaboration across departmen...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $124K *

Shape the future of client partnerships by leading strategic growth initiatives, enhancing relationships, and driving revenue through innovative AI tools and workflows. Collaborate with teams to optim...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$146K - $189K *

Partner with us to enhance our community health provider network. Leverage your expertise in provider relations and network management to drive growth, improve access to care, and support our mission...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Drive growth by developing strategic partnerships in the travel industry. Leverage your expertise to identify opportunities, negotiate agreements, and support travel advisors and agencies in maximizin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $150K *

Transform your career by owning full-cycle sales for top-tier accounts. Drive pipeline growth, engage complex stakeholders, and close high-value deals while collaborating with a dedicated team in a dy...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$175K - $185K *

Pioneer innovative analytics and AI solutions in healthcare. Drive product strategy and collaborate with cross-functional teams to transform complex data into actionable insights and measurable value...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $185K *

Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's transforming healthcare with AI solutions. Drive full-cycle sales, engage decision-makers, and exceed quotas while improving patient access and operational efficiency in dental and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join a dynamic sales team to drive AI-powered solutions in healthcare. Engage with decision-makers, uncover challenges, and demonstrate Myna's value to enhance patient access and streamline operations...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $195K *

Drive enterprise sales success by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology solutions to business outcomes. Leverage your expertise in cloud architecture and AI t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Elevate enterprise AI initiatives by partnering with clients to drive strategic solutions. Leverage your expertise to engage senior leaders, design impactful demos, and accelerate deal cycles, ensurin...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$111K - $150K *

Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Grow your career by driving strategic account management and revenue expansion for mid-market clients. Engage with key decision-makers, develop tailored solutions, and lead negotiations to foster long...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $145K *

Lead the charge in managing key client relationships within Pharmacy Benefit Management, ensuring high-quality service delivery and client satisfaction through effective communication and consultative...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Elevate financial operations by overseeing budgeting, forecasting, and reporting. Collaborate with leadership to drive strategic insights and strengthen compliance while mentoring a dynamic finance te...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $170K *

Join a team that's driving growth in government sales by leading strategic initiatives with the FAA. This role focuses on expanding business opportunities and fostering relationships across complex av...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$145K - $169K *

Optimize strategic partnerships and drive performance across the Coca-Cola portfolio in the North Zone. Lead execution excellence, align priorities, and foster growth through collaboration with bottle...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$100K - $120K *

Drive business growth by assessing market opportunities, developing strategies, and delivering compelling presentations. Collaborate with teams to align marketing efforts and support client proposals...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Lead the translation of investment strategies into tailored client policies, ensuring alignment with firm philosophy. Drive portfolio reviews, client communication, and advisor training while collabor...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.