Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Strategic Account Manager (Industrial)
$80K - $95K *
Transform customer relationships by driving strategic account growth, enhancing engagement, and achieving sales targets. Collaborate with cross-functional teams to meet client needs and deliver except...
1 week ago
$180K - $205K *
Drive financial excellence by delivering insights and analysis for the Field Service organization. Collaborate across departments to enhance forecasting, budgeting, and operational efficiency while su...
2 weeks ago
$67K - $95K *
Champion business growth by driving sales through strategic prospecting and consultative selling. Build and manage a diverse client portfolio, leveraging technology and relationships to exceed quotas...
3 weeks ago
Manager, Client Strategy & Operations
$100K - $120K *
Join a team that's focused on enhancing client delivery and relationship growth. Drive data-driven strategies and cross-functional collaboration to optimize post-sale operations, ensuring exceptional...
Reposted 2 weeks ago
$110K - $120K *
Shape the future of construction by leading complex projects, ensuring safety and quality while managing field operations and collaborating with project teams for successful completion...
4 days ago
Director, Market Growth Strategy, Molecule to Market (CMC)
$185K - $256K *
Join a team that's redefining CMC strategies in life sciences. You'll engage with industry leaders, drive software adoption, and shape market narratives to enhance product lifecycle management and ope...
2 weeks ago
$160K - $175K *
Shape the strategic vision for data products, leading a high-performing team to drive data-informed decisions and enhance product strategy. Collaborate cross-functionally to establish data governance...
1 week ago
$150K - $180K *
Lead the charge in driving growth through strategic partnerships, M&A, and de novo developments. Manage the full business development lifecycle while cultivating relationships with key stakeholders to...
Yesterday
Manager, Client Delivery Experience (Output Solutions and Commercialization) - Remote
$105K - $163K *
Lead and manage client-facing teams to deliver high-quality card processing projects, ensuring successful implementations and client satisfaction through effective project management and strategic ove...
1 week ago
$150K - $205K *
Join a team that's driving M&A success by leading financial strategy, target evaluation, and integration planning. Collaborate with senior leaders to identify opportunities and execute critical phases...
2 weeks ago
$125K - $160K *
Take ownership of strategic client relationships, driving retention and growth while leading negotiations and fostering executive partnerships. Collaborate cross-functionally to deliver exceptional cl...
3 days ago
Sr. Manager, Enterprise Customer Success - Select
$125K - $169K *
Transform customer outcomes by leading a high-performing team dedicated to leveraging Samsara's solutions. Drive strategic growth while ensuring enterprise clients realize sustained value from their i...
Reposted 1 week ago
Enterprise Account Executive, East
$250K - $300K *
Execute innovative strategies to acquire and expand client relationships, leveraging expertise in AI/ML solutions. Be a proactive networker, navigating complex sales cycles to foster business growth a...
Reposted 4 days ago
Senior Sales Executive, Enterprise Payments
$161K - $273K *
Transform client relationships and drive revenue growth by leveraging deep industry expertise and consultative selling skills. Collaborate with teams to deliver tailored payment solutions and lead com...
3 weeks ago
$100K - $120K *
Accelerate progress at the forefront of veterinary sales by driving new business, building relationships, and leveraging innovative solutions to enhance veterinary practices and customer loyalty in a...
3 days ago
$180K - $230K *
Grow your career with a leadership role overseeing global operations, focusing on strategy development, performance management, and cross-department collaboration to drive operational excellence and i...
Reposted 2 weeks ago
Sales Director, Mid-Market - Central (ND, SD, WI, MN, NE, MO, IA, TN, KY, KS)
$160K - $185K *
Join a dynamic team to drive growth by engaging mid-market employers, managing the full sales cycle, and fostering long-term partnerships. Collaborate with cross-functional teams to deliver innovative...
3 weeks ago
$115K - $175K *
Advance market share by driving strategic growth initiatives within the US Mid-Market and Enterprise carrier segments. Lead a high-performing team to execute regional plans, leveraging deep telecom ex...
5 days ago
$120K - $140K *
Transform your career by leading product development initiatives that enhance enterprise reporting and analytics. Collaborate with cross-functional teams to deliver high-quality solutions that meet bu...
2 weeks ago
Cyber Security Sales Team Lead
$190K - $210K *
Drive success by leading a high-impact Cyber Security Sales team, achieving sales targets, and fostering strategic partnerships. Collaborate across functions to align technical and business strategies...
Reposted yesterday
$70K - $400K *
Help us transform the customer experience in annuity sales by guiding clients through the buying process, ensuring clarity, and fostering trust while contributing to the development of a groundbreakin...
Reposted today
$110K - $130K *
Drive new business growth by leveraging your SaaS sales expertise. Engage with property management companies, manage the full sales cycle, and collaborate cross-functionally to ensure client success i...
Today
$80K - $95K *
Transform branch operations by leading a dynamic team to enhance customer service, drive sales, and ensure profitability while maintaining safety and compliance standards. Your leadership will shape t...
2 weeks ago
$183K - $220K *
Lead strategic initiatives for Integrated Delivery Networks and health systems, optimizing patient access and formulary adoption. Build executive relationships and drive clinical integration to enhanc...
1 week ago
$190K - $250K *
Lead strategic partnerships with cloud providers to drive co-sell initiatives, enhance pipeline generation, and foster deep relationships with key stakeholders, ensuring alignment between internal sal...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.