Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$65K - $109K *
Partner with us to foster strategic relationships, optimize account performance, and drive engagement with key stakeholders, leveraging your knowledge of healthcare technology to deliver impactful sol...
Reposted 2 weeks ago
$95K - $100K *
Advance community success by leading operations, ensuring compliance, and fostering a culture of excellence. Drive resident care, financial performance, and team development while building strong exte...
2 weeks ago
$135K - $150K *
Deliver strategic partnerships within Finance & IT, driving revenue growth and market expansion. Collaborate cross-functionally to evaluate and scale fintech, banking, and IT management partnerships...
Reposted 2 weeks ago
Account Executive, Commercial (Pacific Time Zone)
$90K - $110K *
Lead the charge in expanding market presence by owning the full sales cycle, driving revenue growth, and solving complex financial challenges for SMEs through innovative fintech solutions...
6 days ago
Director of SEC Reporting and Technical Accounting
$170K - $210K *
Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...
1 week ago
Director of Customer Experience Operations
$110K - $130K *
Partner with us to transform customer experience operations into a seamless, data-driven journey. Your leadership will unify departments for consistency, enabling effective strategies that enhance cus...
Reposted 2 weeks ago
Director Commercial Compliance
$119K - $186K *
Lead the development of a risk-based compliance framework for U.S. pharmaceutical commercialization, advising senior leaders and ensuring adherence to compliance standards while fostering ethical deci...
2 weeks ago
$100K - $120K *
Lead the charge in driving dealership performance and profitability by overseeing all operations, fostering a high-performing culture, and ensuring exceptional customer satisfaction across all departm...
2 weeks ago
$69K - $99K *
Unlock growth by driving sales across academic, medical, and corporate markets. Build relationships, manage opportunities, and collaborate with teams to exceed targets and enhance customer satisfactio...
1 week ago
Regional Distributor Manager, field based remote in South Texas
$106K - $130K *
Join a dynamic team as you lead distributor strategies and drive sales growth across South Texas, Louisiana, and Mississippi. Collaborate cross-functionally to optimize performance and ensure successf...
1 week ago
Divisional Director, Advisor Acquisition
$120K - $150K *
Drive growth by recruiting experienced financial advisors and teams. Collaborate with field leadership to develop strategies, manage pipelines, and enhance market presence, ensuring successful onboard...
Yesterday
$98K - $183K *
Engage senior-level stakeholders and drive complex sales growth by developing data-driven solutions and strategic account plans, ensuring customer objectives are met and revenue is increased across Co...
Reposted today
National Account Director, Community Oncology
$245K - $290K *
Champion strategic relationships in community oncology to enhance market access for innovative therapies. Drive account strategies, negotiate contracts, and collaborate cross-functionally to ensure op...
1 week ago
Enterprise Account Executive, Georgia
$300K - $350K *
Drive sales growth in the cybersecurity sector by acquiring new accounts, building relationships, and ensuring customer satisfaction. Leverage your expertise to exceed quotas and manage Channel Partne...
5 days ago
Business Development Manager - Southwest
$100K - $160K *
Lead strategic initiatives for service sales growth, engaging customers and leveraging markets to achieve financial targets and enhance the ABB EL Services portfolio across key sectors in the Southwes...
Reposted 1 week ago
$120K - $150K *
Unlock operational excellence by leading multi-site Ambulatory Surgery Centers. Drive growth strategies, optimize performance, and foster strong partnerships with physician leaders while managing sign...
Reposted 1 week ago
$110K - $130K *
Advance your career by enhancing the efficiency and effectiveness of our Legal and Compliance function. Lead operational improvements, manage budgets, and implement legal technology solutions in a dyn...
2 weeks ago
Lead AI and Data Solution Engineer
$200K - $215K *
Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...
3 weeks ago
$100K - $120K *
Join our team to drive growth by reactivating lapsed accounts and expanding our advertising measurement solutions across various sectors. This sales-focused role combines prospecting and program manag...
Reposted today
Vice President, Head of Construction
$160K - $200K *
Oversee the execution of multiple utility-scale solar and BESS projects, ensuring on-time, on-budget delivery while managing contractor performance and maintaining safety and quality standards across...
4 weeks ago
$100K - $110K *
Transform business opportunities within the public transit sector by leading complex sales cycles and fostering relationships with government agencies to drive growth and implement tailored software s...
Reposted 2 weeks ago
Mid-Market Account Executive - Public Sector
$152K - $190K *
Shape the future of IoT by driving complex sales to mid-sized customers, forging impactful relationships, and leading the charge in the digital transformation of essential industries. Enjoy a fully re...
Reposted 2 days ago
$80K - $95K *
Unlock potential by enhancing sales quality through effective training, monitoring, and compliance strategies. Collaborate with teams to drive improvements in agent performance and ensure adherence to...
1 week ago
$110K - $130K *
Unlock your potential by supporting complex customer needs through expert solution design and seamless sales transitions. Collaborate with teams to drive sales opportunities and enhance customer engag...
Today
Sr Manager, Empaveli Publications - US Medical Affairs
$125K - $150K *
Shape the future of scientific communications by leading global publication strategies in nephrology and hematology. Collaborate with cross-functional teams to ensure timely, high-quality deliverables...
Today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.