Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$110K - $130K *
Join a team that's redefining business identity solutions. As a Product Manager, you'll drive strategy, development, and performance of our Business Identity Graph, collaborating with cross-functional...
2 weeks ago
$110K - $130K *
Unlock potential by directing product strategy for data-centric solutions, collaborating across teams to enhance product performance and drive innovation. Own the product lifecycle from conception to...
2 weeks ago
$95K - $115K *
Elevate product management by integrating diverse datasets into innovative solutions. Collaborate with cross-functional teams to enhance existing products and drive new data initiatives from concept t...
2 weeks ago
Customer Success Manager (West Region)
$80K - $95K *
Champion customer success by owning relationships, driving adoption, and ensuring renewals. Leverage deep trust to generate qualified leads while proactively engaging law firm accounts to enhance thei...
Reposted 1 week ago
Director, RevOps Strategy & Operations
$150K - $180K *
Drive operational excellence by leading revenue operations strategy, optimizing processes, and enhancing cross-functional alignment to support scalable growth and measurable outcomes in a dynamic envi...
Yesterday
Associate Director, Strategy & Operations
$179K - $248K *
Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...
4 weeks ago
Sr Regional Oncology Business Manager, Nashville
$130K - $160K *
Unlock potential by driving sales and education in oncology medical devices. Collaborate with healthcare professionals to enhance treatment options for liver and pancreatic cancer while achieving regi...
1 week ago
Director, Manufacturing Operations
$125K - $150K *
Drive operational excellence by leading manufacturing strategies, ensuring compliance, and fostering a culture of safety and continuous improvement. Collaborate across functions to enhance performance...
3 weeks ago
$117K - $206K *
Drive growth by selling predictive solutions, cultivating strong customer relationships, and consistently exceeding sales targets. Leverage your expertise to navigate complex sales cycles and close hi...
Reposted today
$135K - $198K *
Develop and maintain strong relationships with senior decision-makers, driving sales growth and customer satisfaction. Identify new opportunities and align strategies to meet client needs while achiev...
Today
$90K *
Transform client relationships by aligning technology investments with business goals. Leverage a diverse portfolio to drive innovation, optimize solutions, and enhance security, ensuring organization...
2 weeks ago
Enterprise Account Executive - TOLA
$280K *
Lead the charge in driving enterprise sales across the TOLA region, building strong relationships and collaborating with cross-functional teams to deliver exceptional customer experiences and achieve...
2 weeks ago
Senior Manager, Health Plan Operations
$110K - $150K *
Champion operational excellence by leading Payment Integrity initiatives, ensuring accurate claims processing, optimizing workflows, and driving cross-functional collaboration to enhance performance a...
Today
Senior Product Marketing Manager, Healthcare
$150K - $200K *
Drive impactful marketing strategies in the Healthcare sector, enhancing positioning and messaging. Collaborate cross-functionally to accelerate growth and establish thought leadership, ensuring relev...
1 week ago
$134K - $249K *
Champion strategic vendor partnerships and enterprise initiatives, overseeing evaluations, negotiations, and performance metrics to drive clinical, operational, and financial success across multiple t...
Today
Development Manager, Site Selection & Predevelopment
$95K - $115K *
Optimize site selection and entitlement strategies for data center projects, evaluating land opportunities and coordinating with utilities. Drive feasibility assessments and maintain project schedules...
1 week ago
PBS Product Sales Senior Advisor, Consumer Experience Strategy - Evernorth
$110K - $130K *
Unlock your potential by developing integrated strategies that enhance consumer experiences across pharmacy solutions and client initiatives. Collaborate with diverse teams to drive alignment and deli...
6 days ago
PBS Product Sales Senior Advisor, Consumer Experience Strategy - Evernorth
$110K - $130K *
Shape integrated consumer experiences by developing client-specific strategies that align pharmacy solutions with broader initiatives, collaborating across teams to enhance value propositions and driv...
3 days ago
Partner Success Manager, Broker
$95K - $115K *
Empower partner success by managing relationships, enhancing product adoption, and driving engagement. Collaborate with cross-functional teams to deliver exceptional service and support, ensuring part...
3 weeks ago
Real Estate Sales Agent (Investment Properties)
$93K - $450K *
Grow your career by connecting with investors and building a strong client base. Match clients with exclusive properties while benefiting from expert training, performance incentives, and a supportive...
Reposted today
$170K - $200K *
Unlock potential by leading strategic finance initiatives, enhancing planning, forecasting, and reporting processes. Collaborate with executives to drive operational excellence and scale the finance f...
Today
Sr. Director, Customer Success (Technology Vertical)
$150K - $180K *
Transform customer success by leading a high-performing team to drive value, retention, and growth across enterprise accounts. Collaborate cross-functionally to ensure operational excellence and measu...
Today
Account Executive - Business Development Sales, Healthcare SaaS
$150K - $180K *
Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...
5 days ago
Executive Director, Commercial Strategy
$285K - $335K *
Lead the charge in developing and executing commercial strategies that drive brand growth and enhance decision-making capabilities across a dynamic portfolio, focusing on oncology and market insights...
Today
$95K - $150K *
Join a team that's dedicated to empowering small businesses with tailored security solutions. Collaborate with clients to understand their needs and deliver innovative products, while building lasting...
Today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.