Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$110K - $130K *

Join a team that's redefining business identity solutions. As a Product Manager, you'll drive strategy, development, and performance of our Business Identity Graph, collaborating with cross-functional...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by directing product strategy for data-centric solutions, collaborating across teams to enhance product performance and drive innovation. Own the product lifecycle from conception to...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Elevate product management by integrating diverse datasets into innovative solutions. Collaborate with cross-functional teams to enhance existing products and drive new data initiatives from concept t...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Champion customer success by owning relationships, driving adoption, and ensuring renewals. Leverage deep trust to generate qualified leads while proactively engaging law firm accounts to enhance thei...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $180K *

Drive operational excellence by leading revenue operations strategy, optimizing processes, and enhancing cross-functional alignment to support scalable growth and measurable outcomes in a dynamic envi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$179K - $248K *

Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $160K *

Unlock potential by driving sales and education in oncology medical devices. Collaborate with healthcare professionals to enhance treatment options for liver and pancreatic cancer while achieving regi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive operational excellence by leading manufacturing strategies, ensuring compliance, and fostering a culture of safety and continuous improvement. Collaborate across functions to enhance performance...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$117K - $206K *

Drive growth by selling predictive solutions, cultivating strong customer relationships, and consistently exceeding sales targets. Leverage your expertise to navigate complex sales cycles and close hi...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$135K - $198K *

Develop and maintain strong relationships with senior decision-makers, driving sales growth and customer satisfaction. Identify new opportunities and align strategies to meet client needs while achiev...

Missouri, USRemote

Today

  •   Less than 5 years exp.  •   Business Services

$90K *

Transform client relationships by aligning technology investments with business goals. Leverage a diverse portfolio to drive innovation, optimize solutions, and enhance security, ensuring organization...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$280K *

Lead the charge in driving enterprise sales across the TOLA region, building strong relationships and collaborating with cross-functional teams to deliver exceptional customer experiences and achieve...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $150K *

Champion operational excellence by leading Payment Integrity initiatives, ensuring accurate claims processing, optimizing workflows, and driving cross-functional collaboration to enhance performance a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$150K - $200K *

Drive impactful marketing strategies in the Healthcare sector, enhancing positioning and messaging. Collaborate cross-functionally to accelerate growth and establish thought leadership, ensuring relev...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$134K - $249K *

Champion strategic vendor partnerships and enterprise initiatives, overseeing evaluations, negotiations, and performance metrics to drive clinical, operational, and financial success across multiple t...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Optimize site selection and entitlement strategies for data center projects, evaluating land opportunities and coordinating with utilities. Drive feasibility assessments and maintain project schedules...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock your potential by developing integrated strategies that enhance consumer experiences across pharmacy solutions and client initiatives. Collaborate with diverse teams to drive alignment and deli...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Shape integrated consumer experiences by developing client-specific strategies that align pharmacy solutions with broader initiatives, collaborating across teams to enhance value propositions and driv...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Empower partner success by managing relationships, enhancing product adoption, and driving engagement. Collaborate with cross-functional teams to deliver exceptional service and support, ensuring part...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$93K - $450K *

Grow your career by connecting with investors and building a strong client base. Match clients with exclusive properties while benefiting from expert training, performance incentives, and a supportive...

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$170K - $200K *

Unlock potential by leading strategic finance initiatives, enhancing planning, forecasting, and reporting processes. Collaborate with executives to drive operational excellence and scale the finance f...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Transform customer success by leading a high-performing team to drive value, retention, and growth across enterprise accounts. Collaborate cross-functionally to ensure operational excellence and measu...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$285K - $335K *

Lead the charge in developing and executing commercial strategies that drive brand growth and enhance decision-making capabilities across a dynamic portfolio, focusing on oncology and market insights...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $150K *

Join a team that's dedicated to empowering small businesses with tailored security solutions. Collaborate with clients to understand their needs and deliver innovative products, while building lasting...

Today

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.