Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$120K - $140K *

Join a team that's driving growth in unstructured data protection. Leverage your technical expertise to engage with clients, lead discovery, and close deals while collaborating with sales and engineer...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Unlock growth by driving business development initiatives, fostering client relationships, and enhancing market presence. Collaborate with teams to deliver tailored solutions that support long-term su...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$485K *

Transform franchise growth in the Extended Stay sector by leading strategic initiatives, managing a team of Regional Vice Presidents, and building key relationships to enhance development opportunitie...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$110K - $130K *

Drive growth and expand market presence by managing territory sales, developing customer relationships, and collaborating cross-functionally to achieve strategic objectives in the Motion Control secto...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $140K *

Elevate sales growth in the refrigeration and HVAC/R sectors by driving market development, building key relationships, and implementing effective strategies to maximize customer engagement and produc...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$210K - $240K *

Drive the product vision and strategy, collaborating across teams to create innovative solutions that enhance customer experiences and business growth in a dynamic, remote-first environment...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$150K - $180K *

Transform the agent experience by leading strategy across recruitment, onboarding, and ongoing support. Drive engagement and success through cohesive learning and development initiatives, ensuring age...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$200K - $225K *

Manage the valuation process for private equity investments, ensuring accuracy and compliance. Collaborate with investment teams and external providers while leading initiatives to enhance valuation p...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $150K *

Champion growth by leading strategic business development initiatives, forging partnerships, and driving revenue expansion. Collaborate with executives to align goals and enhance market presence while...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$131K - $243K *

Shape the future of customer data management by leveraging your expertise to deliver strategic insights and solutions that drive business value for clients while collaborating with cross-functional te...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$125K - $148K *

Drive strategic partner acquisition by generating new business opportunities in workforce payments, focusing on payroll and pension. Collaborate cross-functionally to build a robust pipeline and lead...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $160K *

Manage labor and employment legal matters, ensuring compliance and providing strategic counsel. Collaborate with HR and stakeholders to develop solutions, supervise outside counsel, and educate on pol...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$160K - $189K *

Engage with regional health plans and PBMs to drive access strategies, manage contract negotiations, and enhance patient access. Collaborate cross-functionally to optimize pharmacy benefit performance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $200K *

Elevate sales performance by leading a high-performing team to achieve strategic goals in the psychiatry portfolio. Utilize analytical skills to identify opportunities and drive execution of effective...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$204K - $220K *

Lead the charge in building a world-class sales enablement function, driving onboarding, training, and content strategy to enhance seller effectiveness and accelerate new hire productivity across a gl...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's dedicated to driving growth in healthcare accounts. Leverage your strategic sales expertise to build relationships, identify opportunities, and deliver value in a fast-paced environ...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Champion the development of healthcare marketing tools by guiding cross-functional teams through the product lifecycle, driving innovative features and optimizing user experiences to enhance HCP engag...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$193K - $340K *

Lead analytics initiatives to empower strategic decisions in a fast-growing agent business. Drive insights, build foundational data systems, and foster a high-performing team to enhance user experienc...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$185K - $256K *

Elevate the market growth strategy for biologics research, driving software adoption and AI use cases. Collaborate with global teams and engage with industry leaders to shape the future of molecular t...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K *

Unlock potential by driving enterprise account strategies and engaging technical leaders. Collaborate with AEs to create meaningful outreach and build a pipeline that converts, focusing on quality int...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$89K - $142K *

Engage with clients as a Territory Manager, driving sales growth and maintaining strong relationships in the industrial filtration sector. Collaborate across divisions to meet customer needs and execu...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$175K - $210K *

Lead a dynamic team to drive presales and solution architecture for enterprise transformation, shaping innovative technology solutions and enhancing client engagements while fostering a high-performin...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock your potential by leading a dynamic sales team to drive growth and profitability. Foster relationships, implement strategies, and achieve sales targets while ensuring alignment with company val...

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Shape the future of sales leadership by driving growth and profitability through effective team management, strategic execution, and customer engagement. Collaborate with stakeholders to enhance perfo...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.