Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$90K - $110K *

Unlock potential by driving new business sales in a dynamic, AI-enabled environment. Own your territory, create a robust pipeline, and engage sophisticated buyers to deliver consistent revenue growth...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Drive operational excellence in Animal Safety manufacturing by leading strategic initiatives, enhancing performance, and fostering a culture of continuous improvement to support business growth and pr...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $135K *

Optimize business operations by providing strategic project support to senior leadership, enhancing recruitment processes, and analyzing market data to drive informed decision-making and improve captu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$207K - $250K *

Unlock your potential as you lead engineering teams in building innovative platforms and AI experiences. Collaborate across departments to drive technical direction and elevate team performance while...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Elevate your career by managing a dynamic team, ensuring exceptional service delivery, and fostering employee development while driving customer satisfaction across diverse sectors...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Lead and innovate sales strategies to drive revenue growth in the Gov/Ed sector. Collaborate with teams to enhance market share, develop strong partnerships, and ensure alignment across sales processe...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $220K *

Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$107K - $150K *

Shape the future of our enterprise data platform by leading product strategy, defining capabilities, and ensuring alignment across business and technology teams to deliver scalable, secure, and truste...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $135K *

Join us to evaluate and underwrite specialty insurance risks, fostering broker relationships and ensuring profitability while maintaining high standards of customer service and operational efficiency...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$121K - $160K *

Advance your career by managing financial operations for project teams, enhancing reporting accuracy, and leading financial analysis to support clinical trials and strategic decision-making...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Advance financial operations by managing project finance teams, enhancing reporting processes, and supporting month-end close activities. Collaborate with stakeholders to ensure accurate revenue recog...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$240K - $300K *

Pioneer a luxury automotive experience as you lead operations, drive sales, and cultivate client relationships in a unique, single-point Porsche dealership. Own the financials and team dynamics while...

6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$80K - $96K *

Lead the charge in transforming sales strategies while mentoring new team members. Utilize your extensive experience to build relationships with clients, ensuring tailored insurance solutions and exce...

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Lead by example in a dynamic sales environment, mentoring new team members while managing your own client relationships. Drive success through effective training and personalized insurance solutions...

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$210K - $230K *

Lead the charge in developing enterprise pricing strategies that optimize profitability and drive growth across diverse service sectors, ensuring alignment with market conditions and client needs whil...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$120K - $140K *

Lead the charge in delivering innovative healthcare solutions by engaging with clients, understanding their needs, and providing technical guidance throughout the sales process to drive successful out...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $190K *

Join us as a strategic advisor, providing legal counsel on commercial contracts, AI products, and technology licensing. Collaborate with cross-functional teams to drive proactive solutions and support...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $120K *

Unlock potential by leading day-to-day accounting operations, ensuring accurate financial reporting, and driving process improvements in a dynamic e-commerce environment. Collaborate across teams to e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $185K *

Elevate executive and client experiences by designing luxury hospitality programs across a national portfolio, ensuring exceptional service standards and memorable interactions in corporate environmen...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$120K - $155K *

Join a team that's dedicated to nurturing and expanding client relationships in the Major Market sector. Drive revenue growth through upselling and cross-selling while ensuring long-term satisfaction...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$125K - $190K *

Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $220K *

Strategize and oversee the development of a cohesive IT and cybersecurity strategy to support a high-growth B2B software organization, ensuring alignment with business goals and compliance standards w...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$82K - $108K *

Accelerate growth by identifying and securing new business opportunities in agriculture. Leverage industry expertise and consultative selling to engage decision-makers, build pipelines, and drive cust...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $230K *

Unlock potential by driving strategic sales in the Life Sciences sector. Engage with key stakeholders, shape IT solutions, and achieve ambitious growth targets while leveraging your extensive network...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$90K - $110K *

Grow your career with a dynamic role focused on sales success and account management. Drive profitable solutions in the retail sector while fostering long-lasting customer relationships and delivering...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.