Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
$135K - $150K *
Deliver strategic partnerships within Finance & IT, driving revenue growth and market expansion. Collaborate cross-functionally to evaluate and scale fintech, banking, and IT management partnerships...
Reposted 1 week ago
Account Executive, Commercial (Pacific Time Zone)
$90K - $110K *
Lead the charge in expanding market presence by owning the full sales cycle, driving revenue growth, and solving complex financial challenges for SMEs through innovative fintech solutions...
4 days ago
Director of SEC Reporting and Technical Accounting
$170K - $210K *
Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...
6 days ago
Director of Customer Experience Operations
$110K - $130K *
Partner with us to transform customer experience operations into a seamless, data-driven journey. Your leadership will unify departments for consistency, enabling effective strategies that enhance cus...
Reposted 2 weeks ago
Director Commercial Compliance
$119K - $186K *
Lead the development of a risk-based compliance framework for U.S. pharmaceutical commercialization, advising senior leaders and ensuring adherence to compliance standards while fostering ethical deci...
2 weeks ago
$69K - $99K *
Unlock growth by driving sales across academic, medical, and corporate markets. Build relationships, manage opportunities, and collaborate with teams to exceed targets and enhance customer satisfactio...
1 week ago
Regional Distributor Manager, field based remote in South Texas
$106K - $130K *
Join a dynamic team as you lead distributor strategies and drive sales growth across South Texas, Louisiana, and Mississippi. Collaborate cross-functionally to optimize performance and ensure successf...
1 week ago
National Account Director, Community Oncology
$245K - $290K *
Champion strategic relationships in community oncology to enhance market access for innovative therapies. Drive account strategies, negotiate contracts, and collaborate cross-functionally to ensure op...
6 days ago
Enterprise Account Executive, Georgia
$300K - $350K *
Drive sales growth in the cybersecurity sector by acquiring new accounts, building relationships, and ensuring customer satisfaction. Leverage your expertise to exceed quotas and manage Channel Partne...
3 days ago
$120K - $150K *
Unlock operational excellence by leading multi-site Ambulatory Surgery Centers. Drive growth strategies, optimize performance, and foster strong partnerships with physician leaders while managing sign...
Reposted 1 week ago
$110K - $130K *
Advance your career by enhancing the efficiency and effectiveness of our Legal and Compliance function. Lead operational improvements, manage budgets, and implement legal technology solutions in a dyn...
2 weeks ago
Senior Counsel, Americas Employment
$196K - $364K *
Lead the charge in shaping employment law strategy across the Americas. Collaborate with cross-functional teams to provide legal guidance on compliance, employee relations, and litigation management...
3 weeks ago
Lead AI and Data Solution Engineer
$200K - $215K *
Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...
3 weeks ago
Vice President, Head of Construction
$160K - $200K *
Oversee the execution of multiple utility-scale solar and BESS projects, ensuring on-time, on-budget delivery while managing contractor performance and maintaining safety and quality standards across...
3 weeks ago
$100K - $110K *
Transform business opportunities within the public transit sector by leading complex sales cycles and fostering relationships with government agencies to drive growth and implement tailored software s...
Reposted 2 weeks ago
Mid-Market Account Executive - Public Sector
$152K - $190K *
Shape the future of IoT by driving complex sales to mid-sized customers, forging impactful relationships, and leading the charge in the digital transformation of essential industries. Enjoy a fully re...
Reposted yesterday
$130K - $200K *
Lead the charge in driving sales performance through strategic account management, collaboration, and innovative program execution within the C&S hospital sector, while fostering relationships and del...
1 week ago
Vice President, Finance & Accounting
$160K - $190K *
Take ownership of financial strategy and operations, leading a dynamic finance team to enhance performance, ensure compliance, and drive growth in a collaborative, employee-owned environment...
5 days ago
Director - Product Management, LillyDirect, EMEA
$163K - $297K *
Champion the development and execution of innovative digital product strategies across EMEA, enhancing consumer experiences and driving key performance indicators in a high-growth e-commerce environme...
1 week ago
Specialty Development Executive - Atlantic Territory
$130K - $140K *
Elevate your career by joining a dynamic sales team driving colorectal cancer screening solutions. Engage healthcare professionals, provide education, and strategize business growth across a vibrant t...
Reposted 2 weeks ago
$87K - $116K *
Join a dynamic team to develop operational strategies and lead a branch, enhancing customer satisfaction and driving sales growth while training to manage diverse teams and projects effectively...
Reposted 1 week ago
Senior Franchise Business Consultant
$90K - $110K *
Join a team that's dedicated to driving franchisee success through strategic coaching, operational excellence, and financial guidance. Collaborate with Regional Developers to enhance performance and i...
1 month ago
$75K - $95K *
Empower customer success through strategic account management and relationship building. Collaborate closely with clients to ensure satisfaction and retention, while driving revenue and addressing uni...
Reposted 3 weeks ago
$180K - $200K *
Lead transformative sales strategies in mid-market sectors, driving team performance and pipeline accuracy. Collaborate cross-functionally to enhance product differentiation and customer engagement, w...
3 weeks ago
$160K - $200K *
Transform customer success and support by leading a dynamic team to enhance retention and expansion strategies. Collaborate with executives to build infrastructure and drive growth for 2,100+ accounts...
3 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.