Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$80K - $95K *

Elevate educational outcomes by driving new business and customer success in the TX territory. Build trusted relationships with decision-makers while delivering innovative literacy solutions to PreK–1...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to transforming literacy in PreK–12 education. Drive new business and foster long-term success by building relationships with key decision-makers and delivering impactful...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $188K *

Accelerate progress at achieving sales goals in oncology by driving product demand and executing launch plans. Collaborate with healthcare providers and internal teams to enhance patient care and ensu...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $235K *

Elevate your legal career by delivering strategic counsel and effective services to Managed Services Organizations and physician practices, while managing complex legal projects and mentoring a team i...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform the accounting function by overseeing monthly closes, ensuring compliance, and managing tax processes. Collaborate with finance leadership to drive accurate reporting and support strategic p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $138K *

Optimize sales strategies and drive growth in the US Academic market by partnering with teams to deliver innovative research solutions, enhance customer relationships, and achieve sales targets while...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$201K - $251K *

Engage with Key Opinion Leaders to drive strategic marketing initiatives, leveraging clinical expertise to influence oncologists and enhance brand strategy. Collaborate cross-functionally to execute i...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$101K - $135K *

Empower customers by enhancing product adoption and retention strategies, driving significant value through strategic engagement, while fostering long-term relationships with key stakeholders in a fas...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $120K *

Shape your career as you take ownership of key accounts, driving sales and building relationships. Collaborate with top performers to modernize government services, while gaining invaluable experience...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $200K *

Shape the future of digital experiences by leading cross-functional initiatives that drive impactful business outcomes through data analysis, customer insights, and strategic alignment across teams...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$76K - $142K *

Lead advanced accounting functions, ensuring compliance with GAAP and SAP. Prepare complex financial reports and analyses while collaborating with auditors. Drive financial accuracy and support manage...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Advance the administration of Defined Benefit and Retiree Medical plans, ensuring accurate valuations, benefit calculations, and compliance with regulations. Collaborate on special projects while leve...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Pioneer a data-driven future by leading product strategy for data science solutions. Drive innovation, oversee development, and ensure alignment with business goals to deliver impactful analytics prod...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$312K - $402K *

Lead the global product strategy from concept to launch, ensuring cross-functional alignment and maximizing asset value throughout its lifecycle. Collaborate with diverse teams to drive successful com...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Pioneer capital relationships across M&A and investment vehicles. Drive fundraising efforts and educate investors on private markets. Build a wealth channel from the ground up while collaborating with...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Drive revenue growth by managing key customer relationships and delivering accurate forecasts. Collaborate with teams to support product development and ensure compliance with industry standards while...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion the full sales cycle for top enterprise accounts, utilizing a consultative approach to solve complex challenges. Drive impactful relationships with stakeholders, and navigate lengthy processe...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$163K - $224K *

Drive strategic planning and execution of acquisitions/divestitures, ensuring seamless integration and value creation across teams. Collaborate cross-functionally to manage milestones, risks, and comm...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $175K *

Lead transformative insurance program initiatives, overseeing technology enhancements and operational workflows. Collaborate across teams to drive project management and ensure compliance, while optim...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$200K - $250K *

Drive critical initiatives by navigating ambiguity, building effective operating models, and ensuring measurable outcomes in a dynamic environment. Engage with leadership to implement AI solutions and...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$190K - $225K *

Join a dynamic team to define and execute impactful product strategies that enhance customer solutions in the financial sector. Lead complex partnerships and drive product expansion, shaping the futur...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $170K *

Shape the future of healthcare market strategies by analyzing trends, defining growth initiatives, and collaborating cross-functionally to drive innovation in life science and medical services. Lead m...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a dynamic team to drive sales of AI solutions to community banks and credit unions. Manage the full sales cycle, from pipeline generation to closing, while exceeding quotas in a fast-paced, high...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Drive operational excellence by leading the FlexCare program, enhancing workforce solutions, and ensuring staffing stability across communities. Collaborate with teams to optimize performance, reduce...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $165K *

Empower clients by leveraging technical expertise to demonstrate product value, cultivate relationships, and drive sales success through effective communication and strategic engagement with stakehold...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.