Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$135K - $160K *

Advance financial operations by managing project finance teams, enhancing reporting processes, and supporting month-end close activities. Collaborate with stakeholders to ensure accurate revenue recog...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead a dynamic sales team, mentoring new members while managing your own client relationships. Drive success through effective training and personalized insurance solutions, ensuring client satisfacti...

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$210K - $230K *

Lead the charge in developing enterprise pricing strategies that optimize profitability and drive growth across diverse service sectors, ensuring alignment with market conditions and client needs whil...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$120K - $140K *

Lead the charge in delivering innovative healthcare solutions by engaging with clients, understanding their needs, and providing technical guidance throughout the sales process to drive successful out...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$160K - $190K *

Join us as a strategic advisor, providing legal counsel on commercial contracts, AI products, and technology licensing. Collaborate with cross-functional teams to drive proactive solutions and support...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $120K *

Unlock potential by leading day-to-day accounting operations, ensuring accurate financial reporting, and driving process improvements in a dynamic e-commerce environment. Collaborate across teams to e...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $155K *

Join a team that's dedicated to nurturing and expanding client relationships in the Major Market sector. Drive revenue growth through upselling and cross-selling while ensuring long-term satisfaction...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

$135K - $145K *

Elevate senior living operations by leading multiple communities to achieve excellence in resident satisfaction, financial performance, and occupancy growth. Collaborate with teams to implement strate...

Des Moines, IARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $190K *

Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Transform the future of food safety and quality assurance by leading compliance programs, enhancing product integrity, and fostering a proactive culture. Collaborate across teams to ensure high standa...

6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$180K - $220K *

Strategize and oversee the development of a cohesive IT and cybersecurity strategy to support a high-growth B2B software organization, ensuring alignment with business goals and compliance standards w...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$82K - $108K *

Accelerate growth by identifying and securing new business opportunities in agriculture. Leverage industry expertise and consultative selling to engage decision-makers, build pipelines, and drive cust...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $230K *

Unlock potential by driving strategic sales in the Life Sciences sector. Engage with key stakeholders, shape IT solutions, and achieve ambitious growth targets while leveraging your extensive network...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$175K - $210K *

Lead the charge in shaping post-quantum security solutions. Drive partnerships, develop the semiconductor ecosystem, and empower the commercial team with technical insights to create demand and establ...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Information Technology

$90K - $110K *

Grow your career with a dynamic role focused on sales success and account management. Drive profitable solutions in the retail sector while fostering long-lasting customer relationships and delivering...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $128K *

Lead and optimize sales teams to drive revenue growth and enhance client relationships. Collaborate with cross-functional teams to implement strategic plans, ensuring customer success and market expan...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$149K - $205K *

Elevate innovation at the forefront of foodtech, agritech, and infrastructure. Lead strategic initiatives, build ecosystems, and drive new ventures to shape the future landscape of Mitsubishi Electric...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $162K *

Join us to develop strategic business plans and conduct effective sales presentations while achieving goals in the pharmaceutical territory. Build relationships, influence key stakeholders, and drive...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead strategic banking initiatives by leveraging your enterprise sales expertise to build relationships and drive new business within Tier 1 global banks, shaping our go-to-market strategy and establi...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$241K - $295K *

Drive drug substance commercial manufacturing excellence by leading technology transfer, operational oversight, and continuous improvement initiatives across multiple CDMO sites, ensuring alignment wi...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$152K - $190K *

Join a team that's transforming industries through IoT solutions, driving impactful sales from prospecting to closing. Engage with executives, build lasting relationships, and thrive in a high-perform...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $210K *

Empower your marketing expertise to drive strategy, revenue, and brand positioning across multiple segments. Lead a dynamic team, collaborate with executives, and shape customer advocacy initiatives t...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $110K *

Drive growth by leading sales and technical initiatives in heating and combustion solutions across the Southeast Region, fostering relationships with key clients and internal teams to achieve strategi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Shape the future of homebuilding by leading a small team of engineers to develop innovative solutions. Balance technical ownership and people leadership while driving impactful projects from concept t...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $120K *

Manage a team of engagement managers to enhance operational effectiveness, drive project execution, and implement innovative solutions. Oversee financial performance and resource allocation while fost...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.