Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$80K - $95K *

Join a team that's dedicated to enhancing public safety through innovative technology. In this impactful role, you'll engage with key stakeholders to drive sales and expand our presence in the emergen...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $180K *

Provide oversight for insurance accounting and reporting, driving process improvements and leveraging technology to enhance financial operations. Collaborate with teams to ensure compliance and accura...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K *

Drive regional sales success by leading a dynamic team, achieving revenue goals, and fostering collaboration. Utilize your expertise in capital medical equipment sales to mentor Territory Managers and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$272K - $340K *

Elevate your career by leading CMC Regulatory strategy and execution. Drive submissions, build a high-performing team, and engage with global health authorities to ensure compliance and success in dru...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance your career by driving business development in clinical research and medical imaging. Build strategic client relationships, identify new opportunities, and contribute to innovative healthcare...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Elevate your career by driving growth strategies that enhance lead generation for multiple brands. Collaborate with cross-functional teams to optimize acquisition channels and improve conversion rates...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$300K - $375K *

Elevate financial strategy and operations by leading a high-performing Finance team, driving capital allocation, and shaping the company's financial narrative to support growth and investor relations...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $95K *

Drive customer success by managing key accounts, ensuring satisfaction, and expanding revenue through upselling. Collaborate with internal teams to align customer needs with solutions, while leveragin...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Empower your career by leading a dynamic sales team, building client relationships, and implementing proven strategies to drive success in the insurance industry while enjoying flexible scheduling and...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $160K *

Accelerate progress at a dynamic tech firm by owning the full sales cycle for mid-market practices. Collaborate with leadership to shape strategy and drive impactful relationships, ensuring success in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $215K *

Elevate growth at top global accounts by leading strategic sales initiatives, building executive relationships, and driving value-based solutions. Collaborate with cross-functional teams to achieve am...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Drive revenue growth by cultivating relationships and managing the full-cycle sales process in the healthcare technology sector. Utilize AI-driven solutions to enhance client performance and deliver v...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Accelerate revenue growth by driving full-cycle sales, from prospecting to closing. Manage complex deals, build relationships, and leverage AI solutions to exceed quotas in a dynamic environment. Own...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$78K - $128K *

Lead the product lifecycle for health plans, driving strategy, development, and market alignment. Collaborate with cross-functional teams to enhance offerings and ensure compliance, while identifying...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$280K - $290K *

Transform partner strategies to build robust alliances and channels globally. Drive growth by developing and managing partnerships while ensuring alignment with corporate objectives and enabling great...

United StatesRemote

Reposted 1 month ago

  •   15+ years exp.  •   Enterprise Technology

$150K - $175K *

Unlock your potential as a hands-on leader in customer service operations, driving performance and quality across teams. Collaborate with cross-functional partners to enhance processes and empower you...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$140K - $220K *

Join a dynamic team focused on driving new business growth through strategic sales initiatives. Engage with key decision-makers, execute impactful presentations, and leverage multi-channel outreach to...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Transform financial operations by leading accounting, reporting, and FP&A. Drive efficiency through AI integration, manage audits, and build scalable processes while supporting strategic growth initia...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$175K - $210K *

Lead the charge in overseeing M&A tax strategies, providing expert guidance on domestic and international deals while mentoring a dynamic team to exceed client expectations and drive practice growth...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$129K - $218K *

Unlock potential by driving strategic sales initiatives and operational improvements. Collaborate with leaders to enhance performance, resource allocation, and growth, transforming data into actionabl...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $134K *

Contribute to business growth by identifying and developing new sales opportunities, collaborating with the Field Sales team, and managing lead funnels in a competitive environment focused on capital...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$142K - $178K *

Lead the development and execution of Salesforce engineering strategies, ensuring high-quality solutions while mentoring teams and collaborating with stakeholders to drive innovation and scalability a...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $230K *

Drive your career with a dynamic role focused on enterprise B2B sales, where you'll cultivate relationships, leverage data insights, and collaborate cross-functionally to close high-value deals in a f...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$83K - $118K *

Unlock your potential by leading complex IT/SaaS projects, driving execution, and enhancing business processes. Collaborate with diverse teams to ensure project success while utilizing Agile methodolo...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Information Technology

$124K - $194K *

Pioneer a regional sales strategy by leading a dynamic team focused on delivering innovative solutions to utilities. Drive revenue growth, enhance customer relationships, and build leadership capabili...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.