Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$130K - $175K *

Unlock potential by managing federal sales strategies, driving relationships, and executing account plans to exceed quotas and revenue goals within the Federal Government and DOD sectors...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $205K *

Transform the future of client technology by leading architectural strategies and integrations in life insurance and annuity environments, ensuring alignment with enterprise goals and delivering scala...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $155K *

Lead the strategic direction and operations for a collaborative utility forum, driving key initiatives in electric distribution while engaging with senior utility leaders to enhance industry practices...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $135K *

Join a dynamic team as you provide strategic insights and operational support across Partnerships, Sales, and Marketing. Drive process improvements and data analytics to enhance partner performance an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $154K *

Analyze and validate complex construction schedules, ensuring project milestones are met. Collaborate with clients to assess schedule health, identify risks, and propose mitigation strategies while ma...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$162K - $290K *

Drive the development of cutting-edge AI-driven safety solutions, leading firmware and full-stack initiatives. Collaborate across teams to shape technology strategy and deliver impactful products that...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Empower your career by driving project delivery and managing Agile teams. Utilize AI tools to enhance decision-making, anticipate risks, and ensure timely outcomes. Collaborate with stakeholders to ma...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance the success of teams by designing and delivering AI-powered learning experiences. Own the enablement lifecycle, collaborating with cross-functional teams to create engaging, measurable trainin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$118K - $180K *

Join a dynamic team to analyze solar PV energy yield assessments for utility-scale projects. Lead performance modeling and mentor engineers while expanding expertise across various renewable energy te...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $120K *

Join a dynamic team to drive sales growth by managing key accounts, developing relationships with C-level executives, and executing strategic sales processes to achieve targets in a defined territory...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$250K - $286K *

Shape the future of sales by leading a dynamic team to drive new business, refine strategies, and enhance customer experiences in a fast-paced SaaS environment, while mentoring leaders and achieving a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $276K *

Advance sales initiatives by managing the full sales cycle, building strong client relationships, and collaborating with internal teams to drive growth in the AI and Salesforce sectors. Make a signifi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$128K - $205K *

Elevate your career by owning the TA tech stack, driving integrations, and enhancing system efficiency. Collaborate with cross-functional teams to optimize processes and lead vendor relationships, all...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $180K *

Join a team that's dedicated to developing scalable software solutions, designing responsive UIs, and optimizing backend services. Collaborate across functions to drive innovation and champion best pr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$126K - $150K *

Pioneer the transformation of tax technology and processes, driving strategic initiatives to enhance operational efficiency, compliance, and user experience through automation and data-driven solution...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$111K - $200K *

Join a dynamic team as a subject matter expert in fuel quality inspections, ensuring compliance with industry standards and enhancing safety protocols across multiple airlines. Collaborate with peers...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$140K - $160K *

Grow your career with a dynamic team focused on project management excellence. Lead initiatives, manage stakeholder expectations, and drive project success through effective planning and execution in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$155K - $185K *

Unlock your potential by leading global ingredient compliance and technical documentation efforts. Drive innovation and regulatory strategies across diverse markets, ensuring product safety and effica...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Support a culture of quality and safety by conducting audits, training staff, and ensuring compliance with standards in a remote construction environment. Drive continuous improvement and maintain eff...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Contribute to customer success as a technical liaison, driving adoption of AI-driven solutions while collaborating with cross-functional teams to enhance product value and performance. Foster strong r...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$144K - $170K *

Join a team that's driving success by selling innovative security solutions to enterprise accounts. Develop and manage accounts with a focus on exceeding revenue goals, leveraging your expertise in a...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Accelerate your career by leading a dynamic sales team to drive IT security solutions. Collaborate with clients and partners to enhance sales strategies, mentor talent, and achieve regional objectives...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $150K *

Execute innovative design and implementation of large-scale Zero Trust solutions. Lead systems engineering initiatives, collaborating with diverse teams to align with DoD requirements and enhance secu...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$106K - $159K *

Help us build and innovate workforce AI platforms, integrating advanced systems and analytics to enable seamless AI adoption and enhance productivity across the enterprise. Drive measurable impact and...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $150K *

Elevate cybersecurity effectiveness by leading proactive Red Team operations that simulate real-world threats, from social engineering to physical security testing, ensuring clients are resilient agai...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.