Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$82K - $131K *
Elevate customer engagement by driving successful project delivery, fostering collaboration across teams, and ensuring satisfaction through proactive communication and effective management of complex...
Reposted 2 weeks ago
Sr. Digital Experience Manager
$110K - $130K *
Champion the digital experience by optimizing user flows, managing web content, and enhancing conversion strategies to drive engagement and pipeline growth for a leading B2B SaaS platform...
2 weeks ago
Sales Development Partner - Entry Level to Leadership
$75K - $100K *
Transform the landscape of B2B partnerships by engaging decision-makers, delivering customized solutions, and fostering long-term relationships in a dynamic, field-based environment. Shape your career...
Reposted 2 weeks ago
Sr. Human Resources Business Partner
$100K - $120K *
Pioneer a high-performing culture by partnering with leaders to deliver strategic HR solutions that enhance employee engagement, retention, and growth in a dynamic, mission-driven environment...
2 weeks ago
Revenue Operations Business Applications Manager
$115K - $125K *
Elevate operational efficiency by managing the integration and support of GTM systems. Drive enablement programs and streamline processes to empower sales teams, ensuring seamless data flow and effect...
2 weeks ago
Senior Digital Paid Ad Manager
$149K - $185K *
Lead the strategy and execution of paid digital advertising programs, optimizing campaigns across multiple channels to drive measurable pipeline and revenue impact. Collaborate with cross-functional t...
2 weeks ago
$92K - $110K *
Unlock potential by leading revenue recognition and compliance efforts, ensuring adherence to ASC 606 and GAAP standards. Collaborate with cross-functional teams to optimize revenue processes and enha...
2 weeks ago
Sr. Director, Sales Systems & Processes
$198K - $298K *
Champion the optimization of Sales systems and processes, driving productivity and strategic initiatives. Collaborate with cross-functional teams to enhance the sales experience and lead a global team...
2 weeks ago
Territory Sales Representative, Implants MIS
$82K - $150K *
Elevate sales growth by aggressively prospecting and converting new dental implant accounts. Focus on expanding market share and positioning value-driven solutions while collaborating with internal te...
2 weeks ago
Regulatory Claims Substantiation Specialist
$103K - $120K *
Advance your career by reviewing and revising scientific claims for dietary supplements. Collaborate with cross-functional teams to ensure compliance and support product development while managing mul...
2 weeks ago
$80K - $95K *
Drive innovative design solutions that elevate brand identity across diverse media. Collaborate with cross-functional teams to create impactful visual assets, ensuring consistency and clarity in commu...
2 weeks ago
Senior Product Enablement & Adoption Manager
$100K - $150K *
Empower members to fully engage with our product through strategic post-sale launches, driving adoption and enhancing user experience. Collaborate with cross-functional teams to ensure successful impl...
2 weeks ago
$61K - $250K *
Champion client success by building personalized financial plans and nurturing relationships. Drive your career forward in a dynamic environment focused on growth, collaboration, and continuous learni...
2 weeks ago
$85K - $127K *
Seeking a skilled analytics manager to lead commercial data analysis, develop reporting solutions, and support pricing decisions. Collaborate cross-functionally to drive insights and enhance team perf...
2 weeks ago
Senior Finance & Strategy Analyst, Consumer
$130K - $154K *
Shape the future of finance by owning financial planning and analysis for Consumer operations, driving efficiency, and enhancing resource allocation through data-driven insights across a dynamic growt...
Reposted 2 weeks ago
Software Engineer, SRE and Production Engineering - DGX Cloud
$184K - $287K *
Drive the future of AI infrastructure by building automation and tools for large-scale GPU systems. Collaborate with cross-functional teams to enhance production reliability and ensure seamless operat...
2 weeks ago
Senior Deep Learning Software Engineer, Inference and Model Optimization
$184K - $356K *
Transform the future of AI by optimizing generative models for efficiency. Collaborate with cross-functional teams to enhance automated deployment solutions, leveraging cutting-edge technologies in de...
2 weeks ago
Director, Partner Marketing (Remote)
$125K - $150K *
Lead and innovate partner marketing strategies across diverse retail segments, managing a team to drive growth and enhance relationships. Collaborate cross-functionally to develop impactful campaigns...
2 weeks ago
$66K - $99K *
Elevate care standards by providing individualized nursing support to residents. Collaborate with families and interdisciplinary teams to ensure effective health maintenance and treatment, while leadi...
2 weeks ago
Principal Clinical Content- Physician (Clinical AI Strategist - UpToDate®) - Partnerships
$173K - $310K *
Transform clinical AI solutions by leveraging your expertise in patient care and research. Collaborate cross-functionally to enhance clinical accuracy and support strategic partnerships, ensuring the...
2 weeks ago
Analyst, Financial Planning & Analysis
$108K - $148K *
Join us as a Senior FP&A Analyst to drive financial planning, reporting, and forecasting. Collaborate across teams to optimize spending and enhance our financial systems, leveraging AI for insights th...
2 weeks ago
Digital Adoption & Lifecycle Manager
$110K - $130K *
Empower customer success by designing and executing lifecycle programs that enhance adoption, retention, and expansion. Collaborate across teams to create impactful communications and leverage data-dr...
2 weeks ago
Territory Sales Representative, Implants MIS
$82K - $150K *
Transform your career by driving growth in the dental implant market. Leverage your sales expertise to open new accounts, convert competitive users, and expand market share while delivering value-orie...
2 weeks ago
Senior Frontend Engineer I - eCommerce
$145K - $170K *
Join a dynamic eCommerce team to enhance the online booking experience. Lead complex features in a Next.js and TypeScript application, impacting conversion and patient trust across multiple countries...
2 weeks ago
Product Support Manager - Digital Tools
$106K - $163K *
Join a team that's dedicated to providing expert technical support and fostering exceptional customer service while leading a skilled group of specialists in delivering innovative product solutions an...
Reposted 2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.