Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$110K - $130K *
Join a team that's at the forefront of cybersecurity, leading advanced incident response efforts. As a senior operational lead, you'll coordinate critical responses, ensuring effective communication a...
1 week ago
Senior Manager, EPC Estimation
$120K - $145K *
Oversee global EPC proposal processes for Battery Energy Storage Systems, collaborating with cross-functional teams to deliver innovative, customer-centric solutions while driving continuous improveme...
1 week ago
$75K - $125K *
Champion sanitation excellence by managing teams, ensuring compliance with health regulations, and optimizing processes in a fast-paced manufacturing environment to uphold safety and quality standards...
Reposted 1 week ago
$170K - $200K *
Transform client relationships by leading data-driven solutions for major tech firms. Engage with executives to uncover insights, drive impactful decisions, and ensure seamless delivery across teams i...
1 week ago
Senior Director, Cloud Engineering
$166K - $200K *
Champion innovative solutions by leading cross-functional teams to enhance operational efficiency and drive project success across multiple departments, ensuring alignment with strategic goals and fos...
1 week ago
Solutions Engineer, Growth - East
$138K - $182K *
Join a dynamic team as you leverage your pre-sales expertise to empower SMB/Commercial customers in cloud security. Deliver impactful demonstrations and training while collaborating with account execu...
1 week ago
Sr Workday HRIS Analyst (Compensation)
$95K - $142K *
Join us to drive impactful HRIS projects, leveraging Workday expertise to enhance global HR operations. Collaborate with stakeholders, implement best practices, and ensure data integrity while champio...
1 week ago
1740 - Director, Strategic Sourcing Facilities- Healthcare
$125K - $185K *
Transform the future of healthcare sourcing by leading strategic initiatives, managing a dedicated team, and driving cost-saving projects across Facilities categories to ensure high-quality service de...
1 week ago
Director of E-Commerce & Digital Product
$130K - $160K *
Elevate digital experiences by guiding site operations and enhancing user engagement. Collaborate with cross-functional teams to implement innovative features and optimize performance metrics, driving...
Reposted 1 week ago
Senior Medical Science Liaisons (MSL) - Cardiovascular, Arizona
$190K - $225K *
Elevate your career by engaging with key opinion leaders and healthcare professionals. This role focuses on scientific collaboration and strategic partnerships, driving impactful medical insights with...
1 week ago
Senior Account Director (Medical Affairs)
$155K - $175K *
Lead the charge in client partnerships while driving strategic growth and team development. Utilize your expertise to deliver impactful insights and solutions in a fast-paced, evolving environment, en...
Reposted 1 week ago
$76K - $90K *
Join a team that's dedicated to delivering exceptional investment management services. This role involves collaborating with Wealth Advisors to strategize and implement portfolio solutions, ensuring a...
1 week ago
Field Application Specialist (Chrom/TFF) -Western Region
$90K - $116K *
Engage with customers to implement and optimize downstream processing technologies, providing technical expertise and support. Collaborate with stakeholders to enhance workflows and ensure successful...
1 week ago
Field Application Specialist - Separations Technology, Virgina or Mayland
$95K - $115K *
Join us to provide expert application support for cutting-edge separation technologies. Engage with customers throughout their journey, ensuring successful implementation and adoption while collaborat...
1 week ago
$145K - $175K *
Join a team that's redefining cloud solutions by architecting innovative CaaS and cloud-native technologies. Collaborate with customers to tackle complex challenges and drive successful cloud transfor...
1 week ago
Minnesota East (St. Paul, MN or Duluth, MN) based Territory Sales Manager - Remote, USA
$120K - $260K *
Unlock potential by driving sales growth in the Minnesota East territory, fostering relationships with physicians, and ensuring high adoption of innovative medical technologies while meeting sales quo...
1 week ago
$100K - $120K *
Champion pipeline growth by designing high-impact demand gen strategies across events, webinars, and campaigns, shaping the future of demand generation in a fast-paced environment focused on accountab...
Reposted 1 week ago
Core Enterprise Account Executive South East
$222K - $278K *
Lead strategic customer engagements to transform enterprise operations, streamline workflows, and generate insights. You'll drive high-value sales, navigate complex negotiations, and cultivate lasting...
Reposted 1 week ago
Recruiting Coordinator - Contractor
$83K *
Transform the candidate experience by coordinating interviews and managing communications. Collaborate with recruiters and hiring managers to streamline processes, ensuring efficiency and excellence i...
1 week ago
$101K - $145K *
Lead the charge in leveraging advanced data science techniques to solve complex business challenges, mentor junior team members, and drive effective risk management through innovative algorithms and d...
1 week ago
$147K - $221K *
Lead the charge in developing and executing go-to-market strategies for innovative products, driving full-funnel demand generation and inbound pipeline growth through cross-functional collaboration an...
1 week ago
$92K - $166K *
Join us in shaping the future of talent acquisition in the Intelligence Community. Lead full life cycle recruiting for highly skilled technical professionals, engaging with top-tier candidates in a fa...
Reposted 1 week ago
Senior Systems Engineer (Antarctic Support Contract)
$92K - $166K *
Transform critical systems for the US Antarctic Program by designing, deploying, and maintaining Linux-based infrastructure. Collaborate with cross-functional teams and lead operations in a unique, mi...
1 week ago
$59K - $106K *
Drive high-voltage transmission line design projects, ensuring compliance with industry standards. Collaborate with multi-disciplinary teams to execute technical tasks, prepare documentation, and enha...
1 week ago
Manager, Executive Compensation
$115K - $130K *
Champion executive compensation strategies by managing program administration, collaborating with HR partners, and conducting market research to enhance compensation practices and support organization...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.