Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$110K - $130K *

Accelerate growth by coaching franchise owners in sales strategies, optimizing processes, and enhancing customer acquisition. Collaborate cross-functionally to develop training programs that foster a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$150K - $165K *

Transform your career by leading technical direction and architecture for complex systems. Collaborate across teams to drive innovation, establish standards, and mentor engineers while ensuring alignm...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $106K *

Optimize legal operations by providing expert advice on contracts, collaborating with teams, and ensuring compliance. Leverage your transactional law experience to streamline processes and support the...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$105K - $136K *

Shape the future of animal welfare by leading innovative research projects focused on companion animal behavior and welfare. Collaborate across teams to translate findings into impactful applications...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$150K - $180K *

Join a team that's shaping the future of platform engineering, driving innovation across cloud, DevOps, and site reliability. This role empowers you to build core services, enhance architecture, and m...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$145K - $157K *

Transform space operations by leveraging Kubernetes to deliver resilient solutions. Collaborate within an Agile framework to enhance software deployment, ensuring optimal performance and security for...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$76K - $86K *

Transform digital marketing strategies for a leading publishing division. Drive innovative campaigns across platforms, enhance e-commerce performance, and collaborate with teams to amplify sales in th...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$96K - $115K *

Lead the management of SaaS applications, ensuring compliance and efficiency. Collaborate across teams to maintain an accurate application catalog and streamline processes, while utilizing AI tools to...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $128K *

Transform the future of air traffic management by ensuring seamless software installations and operational readiness for FAA's Terminal Flight Data Manager program, while collaborating with teams acro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$104K - $166K *

Drive modernization efforts in America's airspace by ensuring accurate software installations and configurations for the FAA's Terminal Flight Data Manager program. Collaborate with teams to resolve t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$66K - $106K *

Contribute to the modernization of America's airspace by executing software installations and updates for the FAA's Terminal Flight Data Manager program, ensuring operational readiness and compliance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$103K - $138K *

Advance public engagement for renewable energy projects by leading stakeholder outreach, assessing local conditions, and developing tailored strategies to ensure project success and community support...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$92K - $115K *

Unlock potential by leading requirements documentation for software projects. Collaborate with stakeholders and technical teams to ensure successful delivery throughout the project lifecycle, while su...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Transform your career by bridging commercial airline operations with military AOC modernization. Leverage your expertise to guide software teams and enhance operational strategies in a dynamic, remote...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$291K *

Engage with a dynamic team as a CRNA in a floating role, providing regional anesthesia across multiple facilities. Enjoy autonomy, diverse cases, and a supportive environment with competitive compensa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$172K - $210K *

Architect and lead customer-focused application development initiatives, translating business needs into robust software solutions. Leverage modern technologies and AI tools to ensure high-quality, se...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$95K - $135K *

Empower a dynamic training and enablement program in a federal health IT setting. Collaborate with multidisciplinary teams to enhance user adoption and learning outcomes through innovative training st...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $135K *

Drive change management initiatives to enhance IT service processes and user adoption. Collaborate with multidisciplinary teams to deliver effective training, communications, and assessments, ensuring...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$85K - $105K *

Drive impactful learning experiences by developing engaging curriculum and materials for federal users. Collaborate with a multidisciplinary team to enhance user adoption of enterprise applications an...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Join a team that's dedicated to designing secure integrations for federal systems. Collaborate with multidisciplinary partners to deliver reliable services and enhance user outcomes in a remote enviro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $140K *

Optimize IT service operations by enhancing ServiceNow workflows and collaborating with a multidisciplinary team to deliver reliable services and measurable outcomes in a remote environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$85K - $105K *

Shape the future of user engagement by crafting targeted communications that enhance technology adoption and readiness. Collaborate with a multidisciplinary team to deliver impactful messaging and mea...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$150K - $175K *

Manage cross-provider IT service delivery and governance in a federal environment. Collaborate with multidisciplinary teams to ensure dependable services and measurable outcomes while leading service...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$108K - $135K *

Elevate your career by overseeing treasury operations, managing liquidity, and enhancing banking relationships. Collaborate with finance teams to align strategies with financial objectives, ensuring o...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $132K *

Join a team that's dedicated to enhancing cybersecurity measures across cloud environments. Lead initiatives in data protection, compliance, and security awareness while mentoring peers and implementi...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.