Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $119,100
$110K - $130K *
Join a team that's shaping the future of financial management in R&D. Drive project budgets, forecasts, and insights while collaborating with cross-functional teams to ensure financial efficiency and...
1 week ago
Major Account Executive, North Central
$135K - $160K *
Drive growth by managing strategic enterprise accounts, navigating complex sales cycles, and building consensus among security-focused buying committees to secure multi-year contracts in a competitive...
1 week ago
$73K - $88K *
Drive the administration of compensation and benefits programs, ensuring compliance and accuracy. Collaborate with HR and Finance to support key cycles and provide insights, enhancing employee experie...
1 week ago
Software Engineer II, Engineering
$125K - $145K *
Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...
Reposted 1 week ago
Senior Global Product Compliance Specialist
$135K - $180K *
Drive compliance excellence by managing global product projects across diverse markets. Collaborate with teams to ensure adherence to regulations for dietary supplements, foods, cosmetics, and medical...
1 week ago
$100K - $125K *
Accelerate progress at our financial reporting function by leading compliance, ensuring accurate statements, and mentoring a skilled team. Drive technical accounting excellence and support executive d...
1 week ago
Lead Business Systems Analyst (Remote) - The Toro Company
$103K - $139K *
Elevate business processes by leading SAP Sales and Distribution solutions. Collaborate with stakeholders to analyze, design, and implement integrated systems, ensuring effective communication and pro...
1 week ago
Director Underwriting - Remote
$124K - $211K *
Transform your career by leading underwriting teams, driving pricing strategies, and ensuring financial performance. Collaborate across departments to influence business growth and deliver sustainable...
1 week ago
Clinical Program Pharmacist Principal- REMOTE
$124K - $211K *
Innovate clinical product strategies by analyzing market data and collaborating across departments. Drive product development and regulatory compliance while enhancing clinical initiatives to ensure c...
1 week ago
$92K - $138K *
Lead the strategic management of accounts receivable functions, optimizing cash flow and ensuring compliance. Collaborate with teams to enhance efficiency, resolve escalations, and drive performance a...
1 week ago
Senior Product Manager, Epic Optimization
$101K - $152K *
Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...
1 week ago
Senior Denials Prevention Process Improvement Advisor
$68K - $103K *
Shape the future of revenue cycle management by driving process improvements and reducing denials. Collaborate with teams to analyze trends, implement best practices, and enhance client satisfaction t...
1 week ago
$95K - $115K *
Drive successful public-sector construction projects by managing scope, schedule, and budget while fostering strong client relationships and ensuring quality delivery from inception to closeout...
1 week ago
Principal Product Manager, Product Development Platforms
$173K - $290K *
Champion innovation in product development platforms, driving strategy and execution for AI-first tools that enhance collaboration and efficiency across teams. Lead the evolution of platforms, ensurin...
1 week ago
Principal Applied Scientist (User Modeling)
$195K - $312K *
Advance user modeling by driving complex AI projects end-to-end, collaborating with cross-functional teams to translate cutting-edge research into impactful solutions for home shopping experiences...
1 week ago
$255K - $300K *
Join a team that's redefining enterprise sales by owning the full sales cycle, engaging C-suite executives, and driving impactful solutions in a fast-paced environment. Your consultative approach will...
1 week ago
Director, Medical - Clinical Research Scientist
$177K - $338K *
Help us advance women's health through innovative clinical trial strategies, where you will conduct, support, and report on global studies for cutting-edge compounds, ensuring adherence to regulatory...
Reposted 1 week ago
Senior Software Engineer, Web Platform
$190K - $267K *
Join a team that's redefining web performance and developer experience. You'll tackle complex platform challenges, optimize Shreddit’s architecture, and enhance tooling for a high-traffic site, empowe...
1 week ago
$69K - $101K *
Empower our Micro-Fulfillment Operations team by ensuring optimal performance and reliability of automated systems. Engage with customers to troubleshoot and resolve complex technical issues, enhancin...
1 week ago
Staff Product Manager, Technical
$160K - $220K *
Lead the charge in defining product strategy and delivery for major client engagements. Collaborate with cross-functional teams, mentor PMs, and navigate complex challenges to ensure successful outcom...
1 week ago
Associate Director, Thought Leader Liaison, Oncology - Central
$157K - $256K *
Champion strategic engagements with oncology thought leaders to enhance insights and drive initiatives for our Solid Tumor portfolio, focusing on collaboration across teams and executing regional stra...
1 week ago
Senior Manager, Corporate Strategy
$125K - $150K *
Empower strategic decision-making by driving data analysis and recommendations. Collaborate with senior leadership to shape initiatives, build financial models, and leverage AI tools, ensuring impactf...
1 week ago
Director, Project Controls, Project & Development Services (Data Centers)
$161K - $190K *
Drive strategic planning and scheduling for large-scale capital programs, focusing on data center delivery. Lead teams, establish best practices, and influence stakeholders to ensure successful projec...
1 week ago
Engineer I - III (Assistant Pavement Management Engineer)
$68K - $94K *
Join a team that's dedicated to enhancing pavement management through data analysis, field inspections, and project prioritization. Collaborate with engineers to ensure performance targets are met whi...
1 week ago
Associate Manager Enterprise RFP Operations
$87K - $136K *
Shape the future of enterprise operations by leading a dynamic team to craft compelling RFP responses, ensuring compliance and strategic alignment while driving productivity and process improvements a...
1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.