Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
Vice President, Franchise Sales Development - Extended Stay
$485K *
Transform franchise growth in the Extended Stay sector by leading strategic initiatives, managing a team of Regional Vice Presidents, and building key relationships to enhance development opportunitie...
1 week ago
$162K - $207K *
Lead the charge in implementing and optimizing SAP Vistex solutions, translating business strategies into technical architecture while managing cross-functional teams and project deliverables for enha...
1 week ago
CIAM & IDAM Services & Enablement Lead
$129K - $185K *
Unlock potential by leading the Customer Identity & Access Management function, overseeing CIAM platform operations, and driving identity strategy across global digital ecosystems while collaborating...
1 week ago
Professional (Senior) Sales Representative, Pain - New Orleans W, LA
$100K - $162K *
Unlock potential by developing effective strategies and relationships to drive sales growth in the territory, ensuring compliance with regulations and high levels of customer engagement through effect...
Reposted 1 week ago
Product Builder, Merchant Portal
$104K - $145K *
Elevate product development by defining, designing, and prototyping features for a merchant portal, leveraging AI tools and user feedback to enhance payment processing solutions rapidly and effectivel...
1 week ago
Sr. Analyst, Pricing Analytics
$89K - $134K *
Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...
1 week ago
Director, AI Platforms & Engineering
$105K - $165K *
Shape the future of AI platforms by leading strategy, architecture, and engineering for scalable, secure solutions. Drive innovation while ensuring compliance and operational excellence across enterpr...
1 week ago
$136K - $187K *
Lead patient education and support initiatives for individuals affected by generalized Myasthenia Gravis. Collaborate with caregivers and healthcare teams to enhance treatment coordination and empower...
1 week ago
$136K - $187K *
Join a team that's dedicated to empowering patients with generalized Myasthenia Gravis through education and support. As a key point of contact, you'll coordinate care, provide resources, and ensure c...
1 week ago
$136K - $187K *
Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...
1 week ago
$168K - $231K *
Join a dynamic team to lead Nurse Case Managers, enhancing patient support and education throughout treatment journeys while ensuring compliance and quality in case management processes...
1 week ago
Supplier Quality Program Manager - Remote
$134K - $176K *
Lead the development and execution of a national supplier quality program, ensuring compliance and fostering strong supplier relationships to enhance operational efficiency and project success across...
1 week ago
Director, National Recruitment
$74K - $131K *
Empower recruitment excellence by leading strategic campaigns nationwide, building strong partnerships, and enhancing team performance. Drive impactful initiatives while adapting to diverse recruitmen...
1 week ago
Power BI / Insurance Analytics Developer
$95K - $115K *
Drive impactful analytics by designing and maintaining Power BI dashboards, leveraging SQL expertise to extract insights from complex datasets, and applying insurance knowledge to enhance reporting so...
1 week ago
Senior Developer- Python Full Stack
$120K - $145K *
Drive the design and implementation of innovative pricing tools, enhancing market readiness and efficiency. Collaborate across teams to establish technical standards and mentor junior developers while...
1 week ago
Regional Hospice RN (AZ/ CA/ NM)
$98K - $112K *
Join a dedicated team providing compassionate hospice care across multiple locations. Collaborate with interdisciplinary teams to ensure quality patient outcomes while adapting to diverse clinical env...
1 week ago
$135K - $216K *
Advance the deployment of MHS GENESIS across multiple sites, ensuring seamless integration and performance outcomes while managing stakeholder relationships and project deliverables throughout the lif...
1 week ago
$135K - $216K *
Lead the charge in integrating DOD MP-ICAM solutions, focusing on CAC/PIV, SAML, and Active Directory. Collaborate with cybersecurity teams to enhance identity controls and support privileged-access w...
1 week ago
Data Migration Lead / Architect
$112K - $179K *
Architect the migration of legacy health data into MHS GENESIS, leading a team to ensure seamless integration and data quality. Collaborate with stakeholders to define architecture and standards, driv...
1 week ago
$135K - $155K *
Drive impactful data solutions by bridging business needs with engineering teams. Own project intake, prioritize requests, and ensure clear communication across departments to enhance efficiency and d...
1 week ago
$115K - $120K *
Elevate software quality by managing test planning, execution, and reporting. Collaborate with development teams, mentor junior testers, and ensure compliance with cybersecurity standards while drivin...
1 week ago
$110K - $135K *
Join a dynamic team to oversee tax engagements, manage client relationships, and mentor junior staff. Utilize your expertise in tax planning and compliance while contributing to various consulting pro...
1 week ago
$175K - $200K *
Transform global talent acquisition by leading a multi-country team, setting strategic vision, and optimizing recruitment processes to meet business growth while ensuring compliance and enhancing cand...
1 week ago
$125K - $133K *
Champion the development of Generative AI solutions, leading an agile team to enhance products and tooling. Drive AI adoption, mentor engineers, and ensure best practices while collaborating across de...
1 week ago
Software Engineer - Technology
$108K - $115K *
Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...
1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.