Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
$110K - $130K *
Champion technical solution design and deployment readiness, translating customer needs into secure, scalable architectures. Collaborate with engineering and cybersecurity teams to ensure successful t...
1 week ago
Staff Software Engineer, Image Build & Release
$229K - $260K *
Drive the technical direction for building and delivering containerized applications, ensuring reliability and security across deployments. Collaborate with teams to enhance automation and mentor engi...
1 week ago
Regional Sales Manager - Southeast
$140K *
Drive regional sales success by leading a dynamic team, achieving revenue goals, and fostering collaboration. Utilize your expertise in capital medical equipment sales to mentor Territory Managers and...
1 week ago
Manager - Total Performance | WC, GL, AUTO and PD
$95K - $115K *
Unlock your potential by leading quality initiatives and training programs to enhance team performance and compliance. Collaborate with management to drive operational excellence and support colleague...
1 week ago
Staff Software Engineer, OTA Services
$229K - $260K *
Lead the charge in designing and implementing a robust OTA update system, ensuring seamless deployment across diverse environments while mentoring engineers and driving technical excellence in distrib...
1 week ago
Director, Strategic Solutions Sales
$110K - $118K *
Engage in driving revenue growth by expanding strategic partnerships and acquiring new enterprise clients. Merge expansion selling with net-new enterprise acquisition to establish a repeatable sales m...
Reposted 1 week ago
Regional Sales Executive- North America
$180K - $225K *
Join a team that's redefining semiconductor IP licensing. Drive complex sales cycles, engage with key stakeholders, and build long-term relationships that generate significant revenue in a fast-paced...
Reposted 1 week ago
$120K - $158K *
Champion operational excellence by leading facilities management across a multi-state portfolio. Drive strategic initiatives, optimize vendor performance, and implement scalable processes to support o...
1 week ago
Strategic Partnerships Manager
$100K - $120K *
Engage in strategic partnership management to drive growth and innovation, overseeing development, negotiation, and execution of pivotal alliances. Collaborate cross-functionally to ensure alignment...
Reposted 1 week ago
Advanced Specialist, Project Management
$125K - $135K *
Lead the strategic planning and execution of complex programs across multiple teams, ensuring alignment with business priorities and effective risk management. Drive delivery improvements and maintain...
Reposted 1 week ago
Staff Revenue Operations Manager, Revenue Planning & Analytics
$125K - $150K *
Transform revenue operations by owning the bottoms-up revenue model, partnering with leadership to drive strategic planning and analysis, and ensuring alignment with growth targets in a dynamic, high...
1 week ago
Account Specialist (Dayton, OH)
$160K - $192K *
Join us to drive commercial performance by engaging healthcare providers, building relationships, and supporting product launches. Collaborate with cross-functional teams to ensure patient access to i...
1 week ago
Go-to-Market & Industry Marketing Manager
$95K - $115K *
Transform go-to-market strategies by executing industry-focused marketing initiatives, driving collaboration across teams to enhance growth initiatives with tailored messaging and customer insights, f...
Reposted 1 week ago
$148K - $263K *
Architect high-performance OneStream solutions by translating complex requirements into scalable designs. Lead a team of consultants, ensuring technical quality and optimizing integrations while excee...
1 week ago
TASKI Corporate Account Manager (NAM)
$80K - $118K *
Unlock potential by driving growth and retention of strategic accounts while identifying new business opportunities. Collaborate with teams to enhance customer productivity and operational performance...
1 week ago
Manager, Implementation Management
$102K - $140K *
Shape the future of customer success by leading implementation strategies, fostering cross-functional partnerships, and driving scalable processes for new customer rollouts in a dynamic B2B SaaS envir...
1 week ago
Sr Manager, Network Success - Denver, CO
$110K - $130K *
Unlock potential by leading a high-performing broker network to optimize revenue growth and enhance conversion success through strategic data analytics and collaboration...
1 week ago
$126K - $150K *
Champion growth strategies for net-new business, driving critical sales across cyber threat intelligence. Influence Fortune 1000 leaders in high-stakes environments while navigating complex sales cycl...
Reposted 1 week ago
$100K - $120K *
Engage with cross-functional teams to drive clinical trial success across regions. Leverage your expertise in project management and mentoring to ensure compliance, quality, and timely execution of st...
1 week ago
Senior Full Stack Software Engineer
$130K - $160K *
Unlock your potential as a Senior Full Stack Software Engineer, leading impactful projects and shaping technology solutions. Collaborate across web applications, backend services, and cloud infrastruc...
1 week ago
$90K - $120K *
Drive revenue growth by optimizing systems and processes across Marketing, Sales, and Customer Success. Leverage data to enhance operational efficiency and establish HubSpot as a reliable source of tr...
1 week ago
$150K - $180K *
Lead the charge in AI innovation within our Insurance portfolio, overseeing the full lifecycle of solutions from ideation to production. Shape strategy, manage multidisciplinary teams, and build new c...
1 week ago
Senior Director, Business Development
$169K - $255K *
Shape the future of personalized consumer products by driving strategic partnerships and revenue growth. Lead business development efforts, cultivate relationships, and expand market reach to position...
1 week ago
Senior Site Contracts Manager (Sponsor Dedicated /Remote - US Based)
$79K - $139K *
Join a team that's dedicated to driving excellence in clinical trial contracts. As a Senior Site Contracts Manager, you'll negotiate and manage site budgets and agreements, collaborating with key stak...
1 week ago
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
$110K - $130K *
Advance your career by leading medical writing projects in a regulatory environment. Collaborate with cross-functional teams to produce high-quality documents, ensuring compliance with industry standa...
1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.