Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$96K - $141K *

Empower local governance by providing expert legal counsel and representation. Engage with city officials on complex legal matters, ensuring compliance and effective management of public sector law. D...

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$85K - $144K *

Engineer comprehensive pricing strategies that maximize revenue and profitability while leveraging data analytics and automation tools. Collaborate with cross-functional teams to establish pricing fra...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $120K *

Engage and drive regional growth for comprehensive due diligence services in the Midwest. Build strategic relationships with key stakeholders in commercial real estate, delivering actionable insights...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Unlock potential by leading complex commercial real estate due diligence projects. Collaborate with multidisciplinary teams to provide technical guidance and client leadership, ensuring high-quality d...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$125K - $150K *

Drive the web strategy and optimization for multiple domains, enhancing user engagement and conversion rates. Lead a dynamic team to implement data-driven improvements and ensure a cohesive online pre...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Elevate HR operations by managing and optimizing HRIS systems, ensuring data integrity, and collaborating across departments to enhance efficiency and support strategic decision-making in a dynamic en...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$162K - $203K *

Join a team that's transforming digital tinnitus care in the U.S. by leading commercial execution across healthcare sectors. Drive adoption and optimize partnerships to enhance patient engagement and...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Drive growth by leading sales and technical initiatives in heating and combustion solutions across the Southeast Region, fostering relationships with key clients and internal teams to achieve strategi...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$186K - $218K *

Architect robust security solutions to safeguard corporate infrastructure and user devices. Collaborate with IT and engineering teams to identify risks and implement effective security measures, ensur...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K - $240K *

Transform AI from concept to production by building and deploying solutions in manufacturing and supply chain. Lead a team to ensure adoption and drive business outcomes through hands-on engineering a...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $185K *

Accelerate your career by executing regional payor strategies to secure coverage and reimbursement for innovative Surgical Glaucoma products. Collaborate with cross-functional teams and build relation...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to optimizing Salesforce for enhanced performance and automation. You'll manage daily administration, collaborate on complex builds, and drive AI integration, ensuring a s...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$163K - $203K *

Elevate security standards by leading classified design and accreditation for defense facilities. Collaborate with cross-functional teams to ensure compliance and streamline processes for rapid deploy...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $95K *

Join a team that's driving brand visibility and growth in the on-premise channel. As an On-Premise Specialist, you'll manage key accounts, optimize sales strategies, and collaborate with distributors...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Reimagine operational excellence by integrating data intelligence and insights across multiple business functions. This role enhances strategic decision-making, optimizes workflows, and supports marke...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Optimize your recruiting expertise to attract top technical talent. Collaborate with engineering leaders to enhance hiring strategies and deliver an exceptional candidate experience while championing...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Drive operational excellence by leading continuous improvement initiatives, optimizing processes, and enhancing safety, quality, and customer satisfaction across multiple business units to achieve mea...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $140K *

Unlock potential by driving growth in the Level Measurement Solutions sector. Build and maintain strategic client relationships, conduct impactful sales presentations, and collaborate across teams to...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Elevate your career as a Lead Meteorologist, overseeing critical weather forecasts and advisories. Collaborate with federal and local agencies to ensure public safety during hazardous weather events w...

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $145K *

Transform our sales strategy by leading a high-performing team to drive revenue growth, enhance customer engagement, and expand market presence in the North American TEST business. Collaborate cross-f...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Lead regional sales efforts by developing strategic plans, managing high-performing teams, and strengthening client relationships to drive revenue growth and market penetration effectively...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$128K - $160K *

Lead the charge in delivering innovative AI and automation solutions, translating complex business needs into technical designs. Collaborate across teams to enhance productivity and drive continuous i...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $110K *

Unlock advanced analytics capabilities by leading data science initiatives that drive informed decision-making and operational efficiency in a regulated environment. Collaborate with stakeholders to d...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$95K - $115K *

Engineer innovative power interconnect solutions by collaborating with customers and internal teams. Drive technical discussions, translate architecture needs, and support product development to enhan...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $326K *

Grow your career with a strategic role driving Data & AI Security channel sales. Collaborate with partners to develop scalable practices, enhance revenue, and shape go-to-market strategies while engag...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.