Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
SOC Automation Solutions Engineer (Super Intelligence)
$110K - $130K *
Drive automated security solutions by designing and implementing Super Intelligence capabilities, enhancing threat detection and response across integrated security technologies while collaborating wi...
3 days ago
Install Base Account Executive 4 ENT
$170K *
Join our Retail Enterprise team to drive sales growth by building strong customer relationships and delivering tailored software solutions. Utilize consultative selling skills to meet business objecti...
3 days ago
National Accounts Sales Manager, DSO East
$165K - $235K *
Drive the execution of DSO growth strategies, leading a team to achieve revenue targets through data-driven sales and cross-functional collaboration, while enhancing customer relationships and ensurin...
Reposted 3 days ago
Territory Sales Representative, Dental Implants MIS
$82K - $150K *
Join a team that's driving growth in the dental implant market by converting competitive accounts and expanding opportunities. Leverage your sales expertise to build relationships and position value-o...
Reposted 3 days ago
Senior Channel Account Manager
$115K - $140K *
Empower strategic channel partnerships by managing relationships, driving revenue, and executing joint business plans. Collaborate cross-functionally to enhance partner performance and ensure seamless...
3 days ago
Sr. Supervisor, Supply Chain (7:00 AM - 4:00 PM EST)
$90K - $112K *
Optimize supply chain operations by managing supplier relationships, ensuring product launch readiness, and driving performance improvements. Collaborate cross-functionally to achieve operational exce...
3 days ago
REMOTE- Senior Platform Software Engineer- Oracle Health
$87K - $209K *
Join a dynamic team to design and implement backend services, enhancing developer tooling and integration frameworks. Drive improvements in performance and resilience while collaborating with cross-fu...
3 days ago
Staff Software Engineer, Applied AI
$160K - $200K *
Join a team that's redefining operational efficiency by architecting robust internal tools and applying AI to real-world challenges. You'll lead technical direction, drive impactful decisions, and enh...
3 days ago
$100K - $120K *
Join a team that's redefining data analysis in educational assessment. You'll troubleshoot and enhance psychometric programs, manage large datasets, and mentor colleagues while ensuring data integrity...
Reposted 3 days ago
Senior Customer Analytics Director
$160K - $214K *
Unlock data-driven insights as a strategic leader in customer analytics, enhancing retention and revenue performance. Collaborate with cross-functional teams to drive accountability and optimize metri...
3 days ago
$120K - $145K *
Shape the future of cybersecurity by providing expert guidance and support to clients. Collaborate with cross-functional teams to enhance customer experience and drive adoption of solutions, ensuring...
3 days ago
$155K - $185K *
Transform the technology landscape by leading cross-functional teams to enhance Medicaid Enterprise Systems, driving system architecture improvements and mentoring engineers towards high-quality, secu...
Reposted 3 days ago
$145K - $160K *
Lead the charge in transforming member support by defining strategy, enhancing team performance, and integrating AI solutions. Drive operational excellence while fostering a culture of empathy and acc...
3 days ago
Virtual Utilization Review Supervisor
$84K - $126K *
Lead the charge in enhancing patient care through effective utilization review, ensuring quality and compliance while collaborating with healthcare teams to optimize clinical outcomes and financial pe...
3 days ago
Software Engineer II, Cloud Applications
$110K - $130K *
Tackle the challenges of building scalable backend services in a cloud environment. Collaborate with cross-functional teams to enhance the Temporal Cloud experience, focusing on reliability, performan...
3 days ago
Executive Assistant to the Chief Business Officer
$136K - $184K *
Join a team that's redefining executive support by enhancing operational efficiency and strategic collaboration. You'll partner closely with senior leaders, managing complex schedules and travel while...
Reposted 3 days ago
$95K - $159K *
Empower the future of medical technology by ensuring the highest quality in embedded systems. Collaborate with cross-functional teams to drive compliance and innovation in software development for lif...
3 days ago
$125K - $155K *
Elevate product initiatives within the casino vertical by driving discovery, stakeholder engagement, and roadmap management. Collaborate with cross-functional teams to enhance player experience and en...
3 days ago
$90K - $125K *
Join a team that's dedicated to building robust software solutions. Collaborate with cross-functional teams to design, develop, and maintain high-quality applications while ensuring reliability and pe...
3 days ago
$100K - $120K *
Engage with new business opportunities to drive growth and market share in the South-Central U.S. Collaborate with teams to launch solutions, manage customer relationships, and achieve sales targets w...
3 days ago
Director of Business Development
$105K - $115K *
Empower a dynamic sales team to drive revenue growth through strategic partnerships and innovative territory planning. Shape the future of business development by fostering relationships and deliverin...
3 days ago
$95K - $100K *
Join a dynamic team as a Senior Strategist, where you'll lead data-driven strategies, mentor talent, and drive innovative solutions in healthcare advertising. Collaborate with creative teams to enhanc...
3 days ago
Sr Lead, Reliability Engineering
$123K - $169K *
Unlock potential by leading reliability improvement programs across a global network of manufacturing sites and distribution centers. Drive hands-on engineering initiatives, optimize maintenance strat...
3 days ago
Vice President, Commercial Pricing - REMOTE
$210K - $230K *
Lead the charge in developing enterprise pricing strategies that optimize profitability and drive growth across diverse service sectors, ensuring alignment with market conditions and client needs whil...
3 days ago
$110K - $130K *
Elevate your career by developing and optimizing machine learning models, collaborating with cross-functional teams to drive data-driven solutions and enhance predictive analytics in a dynamic, Agile...
3 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.