Senior Technical Program Manager Jobs

Explore senior technical program manager jobs for experienced professionals who can align engineering teams, business leaders, and strategic priorities. These roles oversee complex, cross-functional initiatives—from software launches and cloud migrations to infrastructure modernization—while managing scope, timelines, risks, and outcomes. Ladders features vetted professional opportunities paying $100,000 or more, helping you find senior program leadership positions that match your experience.

What Senior Technical Program Managers Do

Senior technical program managers guide programs that span teams, systems, and business functions. They establish plans and governance, clarify ownership and dependencies, communicate progress to executives, and help teams resolve blockers. The role often involves translating business goals into technical milestones while keeping delivery focused on measurable results.

Common Responsibilities and Skills

Responsibilities vary by organization, but may include building roadmaps, coordinating engineering and product teams, monitoring budgets and schedules, managing risk, and defining success metrics. Employers commonly value strong communication, strategic thinking, analytical problem-solving, stakeholder management, and experience with agile or other delivery frameworks. Familiarity with software development, cloud platforms, data, cybersecurity, or enterprise systems may also be useful.

Industries and Career Opportunities

Senior technical program managers work across technology, finance, healthcare, telecommunications, retail, and other industries with complex technical operations. Depending on the company, opportunities may focus on product development, platform engineering, AI and data programs, security, or large-scale transformation. Experienced professionals can progress toward director-level program leadership, portfolio management, or broader technology operations roles.

Find Senior Technical Program Manager Jobs on Ladders

Use Ladders to explore vetted senior technical program manager opportunities with salaries of $100,000 or more. Compare roles by industry, location, work arrangement, and areas of technical focus, then identify positions that fit your leadership background and career goals.

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$134K - $174K *

Champion the product vision and strategy for airspace monitoring, driving cross-functional collaboration to meet customer needs and enhance operational capabilities. Lead product development and perfo...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $145K *

Lead the Validation and Process Engineering teams to ensure compliance and efficiency in pharmaceutical manufacturing. Oversee equipment validation, project management, and cross-department collaborat...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $155K *

Elevate your career as a Senior Software Engineer, driving innovation in cloud-native applications and AI integration. Collaborate with cross-functional teams to enhance mission-critical systems in a...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $280K *

Strategize impactful marketing initiatives to enhance messaging, drive product launches, and empower sales teams. Collaborate with cross-functional teams to create compelling content and analyze campa...

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $185K *

Drive the go-to-market strategy for AI-driven legal solutions, shaping product positioning and messaging. Collaborate with cross-functional teams to enhance market presence and ensure sales success, w...

2 weeks ago

  •   5 - 7 years exp.  •   Media

$179K - $243K *

Join a team that's redefining security with innovative AI-driven products. Lead the strategy for a suite of solutions that enhance security across the AWS ecosystem, balancing customer needs and techn...

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$167K - $222K *

Grow your career with a pivotal role in shaping enterprise software solutions that unify manufacturing processes, enhance operational efficiency, and drive innovation through AI integration, all while...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$130K - $155K *

Unlock potential by leading program management efforts for critical defense systems. Collaborate with teams to ensure successful acquisition, execution, and sustainment of advanced military technologi...

2 days ago

  •   15+ years exp.  •   Information Technology

$125K - $150K *

Partner with us to lead program management efforts in defense acquisition, ensuring compliance with DoD policies while driving successful execution of critical projects that enhance national security...

2 weeks ago

  •   15+ years exp.  •   Information Technology

$150K - $180K *

Empower your career by leading program management initiatives that align with strategic objectives. Oversee budgets, guide cross-functional teams, and enhance organizational performance while driving...

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$150K - $180K *

Elevate the customer experience as a Global Program Manager, spearheading post-sale strategies for major Enterprise clients. Collaborate with internal teams and leaders in Life Sciences to drive imple...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Transform your career by leading acquisition support for cutting-edge C3C technologies. Collaborate with teams to enhance operational effectiveness and drive strategic initiatives in a dynamic defense...

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Drive the delivery of innovative AI/ML product solutions, collaborating cross-functionally to influence technical and product strategies while ensuring timely execution and alignment with broader busi...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $171K *

Lead the charge in delivering complex clinical projects, ensuring quality, time, and cost objectives are met. Collaborate with cross-functional teams and manage client expectations while driving risk...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Accelerate progress at the forefront of semiconductor innovation by leading PDK and Testchip Project Managers. Collaborate with cross-functional teams to ensure timely delivery and drive improvements...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$108K - $130K *

Lead the charge in managing PDK and Testchip Project Managers, driving cross-functional collaboration to ensure timely delivery of innovative semiconductor solutions while optimizing processes and res...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$160K - $190K *

Deliver impactful solutions by leading complex federal application projects. Manage Agile software development, coordinate teams, and ensure disciplined delivery across all phases, from planning to pr...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$188K - $274K *

Optimize complex, cross-functional programs by driving strategic initiatives, managing project timelines, and collaborating with diverse teams to deliver impactful AI and Infrastructure solutions at s...

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Lead the AI/ML product strategy across diverse healthcare integrations, driving innovation and collaboration with cross-functional teams to enhance customer value and revenue growth through data-drive...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$130K - $155K *

Lead the AI/ML product strategy across multiple business units, driving integration and data-centric solutions that enhance customer value and revenue growth through innovative workflows and collabora...

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Yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Drive the AI/ML product strategy across diverse healthcare integrations, collaborating with cross-functional teams to transform complex data into impactful solutions that enhance customer value and re...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$186K - $223K *

Unlock your potential by managing complex hardware production processes, ensuring operational readiness, and driving cross-functional collaboration to meet demand plans and enhance product scalability...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$163K - $236K *

Manage complex engineering projects, driving technical excellence and collaboration across teams. Utilize your expertise in embedded systems and software architecture to enhance product development an...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $135K *

Lead the charge in delivering high-impact data and analytics solutions. Collaborate with clients to shape their data vision, translate it into actionable initiatives, and guide delivery teams in a mul...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $175K *

Accelerate customer success as a Global Program Manager, overseeing post-sale experiences for Enterprise clients. Collaborate with cross-functional teams to drive digital transformation and ensure sea...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a senior technical program manager do?question toggle

    A senior technical program manager leads complex initiatives that involve multiple technical teams and business stakeholders. They coordinate roadmaps, dependencies, risks, schedules, communication, and delivery outcomes.

  • What qualifications are common for senior technical program manager jobs?question toggle

    Employers often seek substantial experience delivering technical programs, strong cross-functional leadership and communication skills, and the ability to manage risk and competing priorities. Requirements may also include experience with software, cloud, infrastructure, data, or agile delivery.

  • How much do senior technical program managers earn?question toggle

    Compensation varies by employer, industry, location, and experience. Ladders focuses on vetted professional jobs paying $100,000 or more, including senior technical program manager opportunities.

  • Where do senior technical program managers work?question toggle

    They work in many sectors, including technology, finance, healthcare, telecommunications, and retail. Their programs may involve software, cloud services, infrastructure, security, data, or enterprise transformation.

  • How can I find senior technical program manager jobs?question toggle

    Browse senior technical program manager listings on Ladders and refine your search by location, industry, work arrangement, salary, and technical specialty to find roles aligned with your experience.