Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$74K - $102K *

Drive process development and improvements on the manufacturing floor, collaborating with engineering and operations teams to optimize efficiencies, enhance quality, and lead capital projects from con...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$142K - $172K *

Partner with us to lead preclinical immune-oncology studies, driving data delivery for translational strategies and collaborating across research teams to support late-stage clinical development and r...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$118K - $173K *

Join a team that's dedicated to delivering large-scale capital projects safely and efficiently. Lead cross-functional teams in project management from planning through operational qualification, ensur...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$93K - $125K *

Elevate your career as a Senior Business Manager, responsible for converting client needs into tailored, high-quality solutions while collaborating with cross-functional teams to drive success from op...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Unlock successful project outcomes by managing the full lifecycle of initiatives, coordinating cross-functional teams, and ensuring alignment with customer and company goals while achieving excellence...

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Transform metallurgical processes by leading hydrometallurgical innovation. Drive laboratory test programs and complex analyses to optimize global technologies while ensuring safe and effective collab...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's redefining BioProcess Engineering, leading pilot-scale production and technology transfer to commercial sites. Drive innovation in biological processes with hands-on leadership whil...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead the charge in providing operational and technical leadership for complex aerospace projects, integrating systems engineering and mission operations to ensure successful execution of NASA's ambiti...

6 days ago

  •   15+ years exp.  •   Aerospace & Defense

$153K - $261K *

Advance the future of continuous glucose monitoring by leading technical and scientific efforts in the design and development of innovative biosensor technologies. Collaborate cross-functionally to dr...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $150K *

Bring your expertise to a dynamic team, driving data analysis for innovative diagnostic assays. Collaborate closely with scientists, execute detailed validation, and develop frameworks crucial for reg...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a leading-edge team to optimize cartridge filling processes in sterile pharma. Leverage your expertise in equipment startup and commissioning while ensuring compliance with production and quality...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform the manufacturing landscape by optimizing processes, validating equipment, and fostering continuous improvement within a regulated environment. Collaborate with cross-functional teams to enh...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$230K - $384K *

Empower innovation by leading a world-class engineering team to drive next-generation gas delivery and flow control product development, enhancing collaboration across functions and ensuring strategic...

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $175K *

Lead the charge in executing core sales operations tasks, enhancing Salesforce, and driving KPIs. This hands-on role transforms strategic decisions into effective operations, ensuring data integrity a...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$121K - $141K *

Make your mark by supporting the development of innovative therapies through formulation lab operations, prototype formulation, and collaboration with cross-functional teams to enhance patient care...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$242K - $338K *

Lead the development of AI evaluation frameworks that ensure clarity, safety, and performance across products. Collaborate with cross-functional teams to drive strategic alignment and build scalable t...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$224K - $313K *

Optimize Expedia Group's AI evaluation standards and frameworks, ensuring quality, accuracy, and safety in AI-powered experiences. Collaborate cross-functionally to drive evidence-based decision makin...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $130K *

Help us transform product development by optimizing stamped components. Collaborate across teams to enhance manufacturing processes and drive innovation through predictive engineering and simulation t...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Drive new product development in stamped components, optimizing die design and manufacturing processes. Collaborate with engineering teams to troubleshoot, develop, and enhance stamping technology whi...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$121K - $176K *

Join a dynamic team to engineer groundbreaking machine vision software that enhances scientific research. Collaborate closely with scientific stakeholders, lead software development projects, and driv...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$161K - $202K *

Join a leading lab as you oversee Clinical Chemistry operations, ensuring quality compliance and driving technical excellence while guiding and training staff in a specialized environment focused on p...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$224K - $313K *

Shape the future of AI evaluation by building frameworks that set high standards for accuracy, safety, and trust across the organization. Collaborate with engineering and data science teams to ensure...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $105K *

Unlock potential by leading analytical development efforts, employing scientific creativity and technical skills. Collaborate on complex projects and drive innovative solutions while adhering to regul...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Join a team that's revolutionizing water treatment! Oversee pilot-scale plants, enhance your engineering expertise, and engage in hands-on projects while collaborating with seasoned professionals in a...

Richmond, BCIn-Person

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$94K - $128K *

Drive project execution in an FDA-regulated environment, coordinating timelines, documentation, and interdepartmental communication to ensure successful outcomes and regulatory compliance while managi...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.