Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$150K - $250K *
Lead the charge in designing and building critical AI-driven infrastructure. Engage with researchers to deliver robust, high-performance systems that automate trading and empower data-driven decision...
3 weeks ago
$68K - $112K *
Deliver precise scientific data validation and support for environmental projects across federal, state, and commercial sectors to ensure compliance and quality assurance...
2 weeks ago
Scientist, Downstream Vaccines and Advanced Biotechnologies (VAX) Process R&D
$87K - $137K *
Join our dynamic team to lead downstream process development for novel vaccine adjuvants. Collaborate with cross-functional teams to innovate and enhance safe, scalable, and efficient manufacturing pr...
4 days ago
$90K - $110K *
Lead and mentor a dynamic team while managing laboratory operations and ensuring technical excellence in testing. Collaborate with cross-functional teams, drive innovation in packaging materials, and...
2 weeks ago
$80K - $95K *
Advance your scientific career by leading virology research, focusing on vaccine development and animal health innovations. You'll design experiments, analyze data, and translate findings into effecti...
1 week ago
Group Leader, BioChemical Analysis
$95K - $115K *
Lead analytical efforts in Biopharma by managing a team of scientists, ensuring quality compliance, and supporting project execution while mentoring talent and driving innovation in a dynamic environm...
3 weeks ago
Scientist, Peptide Chemistry (Night Shift)
$95K - $115K *
Drive the overnight peptide synthesis operations, ensuring efficient workflows and accurate documentation. Collaborate effectively with day teams while troubleshooting and maintaining high-quality sta...
1 week ago
Senior Manager Marketing, PDAC
$150K - $189K *
Transform healthcare marketing by leading strategies for oncology products. Collaborate cross-functionally to deliver impactful campaigns, manage external agency partnerships, and drive customer engag...
2 weeks ago
$120K - $145K *
Champion strategic initiatives in program management to advance product development and operational excellence. Collaborate with senior leaders to deliver impactful programs, align goals, and drive tr...
3 weeks ago
Senior Chemist, Research & Development
$80K - $95K *
Explore innovative formulations in cosmetic science, developing skin, body, and hair care products. Leverage your expertise in regulatory requirements and competitor analysis to drive new business opp...
2 weeks ago
Senior Technical Program Manager
$67K - $166K *
Elevate your career by leading cross-functional programs that drive business growth. Leverage your technical expertise and program management skills to manage project milestones and stakeholder engage...
6 days ago
$101K - $169K *
Join a dynamic team to enhance precision in calibration methods and develop innovative solutions in metrology. Drive quality assurance in a lab environment while providing technical support and foster...
3 weeks ago
$244K - $305K *
Join a team that's advancing drug development by leading nonclinical safety strategies and providing expert toxicology insights to drive informed decisions across research and clinical phases...
3 weeks ago
Senior Principal Mechanical Engineer (SIGN-ON BONUS)
$125K - $150K *
Join a team that's shaping the future of engineering by leading mechanical design and execution for capital projects in oil, gas, and chemical industries. Drive innovation and ensure safety while ment...
Reposted 3 weeks ago
Senior Technical Program Manager
$250K - $375K *
Execute program management for technical projects, ensuring timely delivery and quality. Establish processes, coordinate with teams and external partners, and mitigate risks in a fast-paced, high-assu...
6 days ago
Senior Associate Scientist Bioprocess Analytics
$75K - $108K *
Contribute to bioprocess development by executing advanced analytical testing and method optimization, ensuring scientific milestones are met efficiently within a collaborative, multidisciplinary envi...
4 days ago
Scientist/Manager, Assay Product Development
$137K - $220K *
Lead and optimize innovative assay product development in a collaborative, multidisciplinary setting, ensuring high-quality product launches and effective communication with cross-functional partners...
5 days ago
Principal Scientist, CMC Regulatory Affairs - Combination Products (1 of 2)
$117K - $201K *
Join a team that's committed to driving innovation in regulatory science for drug-device combination products, collaborating cross-functionally to develop and execute strategies for successful global...
Reposted 3 days ago
Principal Scientist, CMC Regulatory Affairs - Combination Products (1 of 2)
$117K - $201K *
Unlock potential by providing strategic CMC regulatory expertise to accelerate the development and lifecycle management of drug-device combination products, ensuring compliance with global regulations...
Reposted 3 days ago
Principal Scientist, CMC Regulatory Affairs - Combination Products (1 of 2)
$117K - $201K *
Elevate your career as a Principal Scientist in CMC Regulatory Affairs, leading strategies for drug-device combination products, guiding cross-functional teams, and ensuring compliance with global reg...
Reposted 3 days ago
Principal Scientist, CMC Regulatory Affairs - Combination Products (1 of 2)
$117K - $201K *
Shape regulatory strategies for drug-device combination products, ensuring compliance with global standards while collaborating across teams to support development and lifecycle management in a hybrid...
Reposted 3 days ago
Senior Project Manager, Laboratory
$88K - $105K *
Drive success by managing clinical laboratory studies, ensuring client satisfaction, and maintaining effective communication. Oversee project parameters, monitor budgets, and support teams while adher...
6 days ago
$120K - $145K *
Drive the design and execution of clinical studies, leading innovative treatments while collaborating across functions. Elevate early clinical development strategies and ensure adherence to timelines...
3 weeks ago
$110K - $130K *
Deliver strategic leadership in clinical studies, focusing on innovative hematology-oncology treatments. Ensure high-quality program execution, regulatory compliance, and cross-functional collaboratio...
3 weeks ago
$110K - $130K *
Drive innovative clinical studies that evaluate cutting-edge treatments, providing strategic leadership in early clinical development while ensuring compliance with scientific standards and regulatory...
3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.