Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$100K - $130K *

Lead the coordination and management of scientific projects, providing expert support in engineering and automation. Oversee project lifecycle to ensure alignment with strategic goals, delivering impa...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Elevate your career by leading a strategic engineering team, defining technical vision, and driving product delivery in a collaborative, fast-paced environment focused on growth and innovation...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead complex programs connecting customers with operational excellence. Drive high-quality delivery while managing cross-functional teams in a fast-paced, matrixed environment. Inspire collaboration f...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $142K *

Innovate with us as a Materials Scientist, developing cutting-edge materials for 3D printing. Work collaboratively across teams to enhance product performance and drive advancements in various industr...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$148K - $171K *

Lead analytical method development and validation for drug substances and products. Collaborate with cross-functional teams, mentor analysts, and oversee contract activities to contribute to late-phas...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Lead the charge in innovative protein chemistry, driving personal care technologies from concept to market. Collaborate cross-functionally, utilizing expertise in protein modifications and advance ana...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Lead the charge in developing innovative functional beverage formulations, from initial prototype to production-ready, emphasizing analytical rigor and sensory evaluation while navigating complex ingr...

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$70K - $95K *

Empower progress at the forefront of environmental protection by conducting site assessments, analyzing data, and recommending remediation strategies to ensure compliance with regulations while collab...

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$90K - $120K *

Champion project execution by coordinating lab research, managing client needs, and ensuring quality standards are met. Oversee budgets, schedule activities, and lead technical teams while optimizing...

Quebec, QCIn-Person

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$143K - $194K *

Transform drug development by leading the creation of LC-MS-based assays to quantify therapeutics and biomarkers, driving innovation and collaboration in cross-functional research teams to enhance the...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $148K *

Unlock potential by leading the development of advanced flow cytometry and ligand-binding assays, collaborating with multidisciplinary teams to enhance clinical biomarker strategies and drug developme...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$156K - $343K *

Empower the advancement of digital pathology by developing innovative image-analysis solutions using cutting-edge machine learning and deep learning techniques to drive significant insights in drug di...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Engage in a global leadership program that deepens technical expertise and fosters local team development. Spend two years in China mastering technology transfer, then lead international projects and...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Drive global leadership development by mastering biopharmaceutical processes in China before leading technology transfer at overseas sites. Engage in high-impact projects, process scale-up, and establ...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$194K - $329K *

Drive innovation at the forefront of AI Safety in national security. Lead multidisciplinary research teams while shaping strategies that translate advanced data science into mission-ready capabilities...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$194K - $329K *

Engage as a strategic leader in AI Safety, guiding multi-year R&D programs, fostering partnerships, and leading interdisciplinary teams to advance national security missions through innovative data sc...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$135K - $185K *

Discover opportunities as a Principal Hydrogeologist, leading projects with multi-disciplinary teams, driving strategic growth in mining hydrogeology services, and enhancing client relationships while...

US-AnywhereRemote

1 week ago

  •   15+ years exp.  •   Energy & Utilities

$128K - $155K *

Help us lead complex projects in Cell Therapy as a Principal Scientist, optimizing methods, ensuring compliance, and driving innovative solutions in a collaborative, fast-paced environment while mento...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $150K *

Join a dynamic team as a Principal Scientist, leading innovation in Cell Therapy. You'll optimize and validate analytical methods, drive complex projects, and mentor cross-functional teams to ensure e...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$128K - $155K *

Drive innovation as a Principal Scientist, leading advanced projects in method optimization and validation for Cell Therapy. Collaborate cross-functionally, mentor teams, and ensure regulatory complia...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Help us shape the future of aquatic ecosystems through advanced research and project management. Lead field studies, mentor staff, and collaborate on impactful scientific reports that enhance salmonid...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$94K - $144K *

Advance your career by applying human quantitative genetics to enhance drug discovery efforts in neurology and immunology. Collaborate with experts to deliver analytical insights that drive critical p...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Empower the evolution of cybersecurity solutions, driving impactful innovations and managing product offerings to meet critical market demands and advance defensive strategies across multiple sectors...

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$210K - $331K *

Transform the future of inhalation therapy by leading global regulatory CMC strategies for innovative DPI combination products, ensuring compliance throughout their lifecycle from development to appro...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Join a team that's shaping the future of cybersecurity solutions. As a Principal Product Manager, you'll drive innovative offerings, serving diverse market segments while leveraging your extensive exp...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.