Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$114K - $234K *
Join a team that independently evaluates advanced AI models and systems. You'll translate complex customer needs into measurable tests, develop automated protocols, and collaborate with experts to enh...
1 week ago
$114K - $234K *
Explore advanced AI evaluation techniques by leading end-to-end analyses of foundation models and AI systems. Collaborate across teams to translate complex questions into actionable insights, enhancin...
1 week ago
Scientist, Analytical Development
$90K - $96K *
Elevate your career by joining a dynamic team focused on developing and qualifying analytical methods for innovative bioprinted tissue therapeutics, ensuring product excellence as we advance toward cl...
4 days ago
Staff Scientist/Senior Manager, Biology
$130K - $150K *
Unlock innovative solutions in biology research as a strategic leader, managing R&D programs and fostering teams for successful product development and commercialization in a fast-paced life sciences...
Reposted 1 week ago
$110K - $130K *
Join a team that leads complex global projects in aseptic manufacturing, ensuring timely delivery and budget compliance while inspiring collaboration across multidisciplinary teams to achieve shared g...
3 days ago
Principal Research Scientist, Molecular Pharmacology
$130K - $155K *
Transform the future of drug discovery by leading a dynamic team in molecular pharmacology, driving innovation through robust assay development and cross-functional collaboration in various therapeuti...
4 days ago
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Transform the future of environmental consulting by leading site assessment and remediation efforts across Massachusetts. Leverage your expertise to guide multidisciplinary teams, ensuring quality del...
Yesterday
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Transform the environmental landscape as a Licensed Site Professional, leading site assessments and remediation in Massachusetts. Collaborate with cross-functional teams to exceed client expectations...
Yesterday
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Unlock your potential as a Principal Engineer/Scientist leading site investigations and remediation projects in Massachusetts. Manage multi-disciplinary teams, ensure project quality, and mentor junio...
Yesterday
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Drive environmental solutions as a Principal Engineer, leading site remediation and assessment teams in Massachusetts projects. Collaborate with clients and enhance project delivery while mentoring ju...
Yesterday
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Contribute to critical environmental projects as a Licensed Site Professional. Lead multi-disciplinary teams, manage project scopes, and mentor junior staff while ensuring compliance with Massachusett...
Yesterday
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Shape the future of environmental consulting as a Licensed Site Professional. Lead complex site investigations and remediation projects across Massachusetts while managing multidisciplinary teams and...
Yesterday
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Drive impactful environmental solutions as a Principal Engineer/Scientist overseeing Massachusetts projects. Lead multi-disciplinary teams, engage clients, and ensure high-quality remediation practice...
Yesterday
Principal Engineer/Scientist - MA Licensed Site Professional
$131K - $222K *
Lead Massachusetts projects as a Licensed Site Professional, managing site investigations and remediation efforts. Collaborate with multidisciplinary teams to execute effective environmental solutions...
Yesterday
Principal Research Scientist I, Process Chemistry (Biocatalysis)
$120K - $145K *
Drive cutting-edge biocatalysis research and development for scalable API synthesis, integrating AI/ML tools and modern techniques while collaborating on innovative solutions for complex chemical synt...
6 days ago
Principal Scientist, Oral Formulation Sciences
$173K - $272K *
Lead the charge in developing innovative drug formulation solutions, overseeing project teams and driving new technology strategies to enhance pipeline progress and manufacturing processes for new med...
3 weeks ago
Senior Scientist - Downstream Process Development, mRNA
$110K - $130K *
Join a team that's advancing mRNA technology by leading process development and optimization for therapeutics and vaccines. Utilize your expertise to mentor others and drive project success in a colla...
Reposted yesterday
Senior Scientist I- Program Manager
$110K - $130K *
Manage complex R&D programs by overseeing operations, compliance, and reporting. Collaborate with diverse teams to achieve program goals, ensuring efficient execution and integration of scientific and...
3 weeks ago
$90K - $105K *
Elevate your career by contributing to innovative proteomic workflows, enhancing sample preparation processes to support biomarker discovery. Collaborate across teams while applying advanced analytica...
3 days ago
Principal Scientist - In Vivo Pharmacology
$180K - $235K *
Lead the charge in developing non-clinical in vivo strategies, managing pre-clinical studies, and improving experimental models while driving innovation and collaboration across research teams to eval...
Reposted 2 days ago
$125K - $150K *
Transform complex systems by architecting AI-driven solutions that integrate cameras, edge devices, and cloud analytics. Analyze, model, and implement innovative frameworks while collaborating across...
Reposted 1 month ago
Senior Scientist / Principal Scientist / Associate Director, Biotransformation
$150K - $220K *
Champion innovative biotransformation strategies to enhance drug discovery and development. Drive metabolite profiling, oversee CRO studies, and collaborate with multidisciplinary teams to optimize ch...
1 week ago
Senior Scientist - Neurobiology and Metabolism
$140K - $190K *
Champion drug discovery in neurobiology and metabolism, driving complex preclinical studies, leading cross-functional teams, and integrating mechanistic insights to tackle obesity and cardiometabolic...
1 week ago
Analytical Sciences, Small Molecule
$175K - $210K *
Develop analytical control strategies for a clinical-stage small molecule program, leading method development and validation efforts while ensuring quality compliance, regulatory documentation, and ef...
Reposted 4 days ago
Senior Scientist II, Computational Chemistry
$170K - $212K *
Transform drug discovery by leading computational strategies and optimizing novel therapeutics. Collaborate cross-functionally and drive innovative solutions to accelerate the advancement of impactful...
Yesterday
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.