Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$110K - $140K *

Join a team that's shaping the future of mRNA analysis by developing innovative characterization methods for lipid nanoparticles. Collaborate across research to enhance the understanding and applicati...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Accelerate scientific discoveries by applying your expertise in analytical methods to support innovative new synthetic modalities. Collaborate with cross-functional teams to drive projects from discov...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $107K *

Partner with us to enhance microbial fermentation processes for recombinant proteins. This hands-on role emphasizes bench-scale bioreactor operations and data analysis in a fast-paced research environ...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Join a team that's driving innovation in product development across diverse R&D projects. Collaborate with cross-functional teams to ensure timely execution, effective risk management, and alignment i...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Optimize product launch processes by leading cross-functional projects, ensuring timely delivery while navigating risks and maintaining stakeholder alignment across diverse global teams...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Take ownership of cross-functional NPI projects driving global product launches from inception to execution. Lead teams through project governance, risk management, and stakeholder alignment while ens...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$148K - $257K *

Join a team that's shaping the future of peptide synthesis, driving innovative solutions and sustainability in drug development from bench-level research to commercial production, ensuring safe and ef...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$113K - $149K *

Advance the future of targeted therapeutics by leading innovative lipid nanoparticle research, focusing on formulation, delivery, and mechanistic challenges. Collaborate with a multidisciplinary team...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $149K *

Join a team that's dedicated to advancing lipid nanoparticle formulations, targeting delivery strategies, and in vitro/in vivo performance assessments, collaborating with experts to overcome delivery...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Collaborate with teams to ensure product quality through comprehensive QA testing and analytical support. This role involves sample preparation, data analysis, and adherence to safety standards while...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $256K *

Join a team that's shaping the future of AI-driven scientific platforms. You’ll design, build, and optimize backend systems and data infrastructures, collaborating with experts to elevate orchestratio...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $120K *

Empower innovation in elastomer development as a senior technical leader, bridging material science and manufacturing processes for electrical safety products. Drive high-performance formulations whil...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$228K - $309K *

The Principal Applied Scientist will leverage a strong machine learning background to develop cutting-edge Conversational AI Systems, focusing on Natural Language Understanding and Generative AI. This...

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$200K - $280K *

Architect strategies to unlock the potential of structured and unstructured data, guiding multiple software development teams in delivering quality solutions that meet mission-critical needs for gover...

3 weeks ago

  •   15+ years exp.  •   Aerospace & Defense

$160K - $210K *

Champion the development of a robust Analytical Development and QC function, drive regulatory readiness, and ensure operational excellence in a dynamic environment focusing on gene therapy programs an...

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Lead the charge in managing diverse projects from initiation to completion, ensuring they are delivered on time and within budget. Collaborate with team members and stakeholders to drive effective com...

Edmonton, ABIn-Person

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$235K - $331K *

Pioneer the development of advanced ML models for lending and underwriting. Spearhead financial forecasting, leading a quantitative team to enhance valuation insights and market dynamics for collectib...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$70K - $95K *

Grow your career with a dynamic team focused on analyzing powder and liquid samples to determine their physical properties using advanced techniques and methodologies...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$235K - $331K *

Drive the development of quantitative models for lending & underwriting, enhancing financial forecasting and market dynamics analysis while leading a high-performing team to empower our growth within...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$164K - $238K *

Lead the charge in transformative Generative AI research, driving innovative technologies and collaborating with expert teams. Contribute to world-class publications while mentoring future talent, sha...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Drive innovation in computational chemistry by leading the design and optimization of drug candidates, collaborating with cross-functional teams to enhance drug delivery strategies and advance first-i...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$148K - $203K *

Join a team that's driving analytical excellence and regulatory compliance in biotech. Collaborate across functions to lead analytical development, QC oversight, and lifecycle management, enhancing pr...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$62K - $114K *

Join a team that's leading scientific and technical support for NOAA's NMFS. Engage with diverse stakeholders to assess marine resources and propose environmental solutions while overseeing critical c...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Advance innovative solutions as a Senior Scientist, providing expert support to DARPA's Microsystems Technology Office through project management and strategic guidance on complex research initiatives...

3 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$139K - $209K *

Lead the charge in advancing cardiovascular and renal research by leveraging your in vivo expertise. Collaborate with interdisciplinary teams to design experimental studies and drive innovation in dru...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.