Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$114K - $234K *

Join a team that independently evaluates advanced AI models and systems. You'll translate complex customer needs into measurable tests, develop automated protocols, and collaborate with experts to enh...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$114K - $234K *

Explore advanced AI evaluation techniques by leading end-to-end analyses of foundation models and AI systems. Collaborate across teams to translate complex questions into actionable insights, enhancin...

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$90K - $96K *

Elevate your career by joining a dynamic team focused on developing and qualifying analytical methods for innovative bioprinted tissue therapeutics, ensuring product excellence as we advance toward cl...

Vancouver, BCIn-Person

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Unlock innovative solutions in biology research as a strategic leader, managing R&D programs and fostering teams for successful product development and commercialization in a fast-paced life sciences...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that leads complex global projects in aseptic manufacturing, ensuring timely delivery and budget compliance while inspiring collaboration across multidisciplinary teams to achieve shared g...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Transform the future of drug discovery by leading a dynamic team in molecular pharmacology, driving innovation through robust assay development and cross-functional collaboration in various therapeuti...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$131K - $222K *

Transform the future of environmental consulting by leading site assessment and remediation efforts across Massachusetts. Leverage your expertise to guide multidisciplinary teams, ensuring quality del...

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$131K - $222K *

Transform the environmental landscape as a Licensed Site Professional, leading site assessments and remediation in Massachusetts. Collaborate with cross-functional teams to exceed client expectations...

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$131K - $222K *

Unlock your potential as a Principal Engineer/Scientist leading site investigations and remediation projects in Massachusetts. Manage multi-disciplinary teams, ensure project quality, and mentor junio...

Yesterday

  •   11 - 15 years exp.  •   Real Estate & Construction

$131K - $222K *

Drive environmental solutions as a Principal Engineer, leading site remediation and assessment teams in Massachusetts projects. Collaborate with clients and enhance project delivery while mentoring ju...

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$131K - $222K *

Contribute to critical environmental projects as a Licensed Site Professional. Lead multi-disciplinary teams, manage project scopes, and mentor junior staff while ensuring compliance with Massachusett...

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$131K - $222K *

Shape the future of environmental consulting as a Licensed Site Professional. Lead complex site investigations and remediation projects across Massachusetts while managing multidisciplinary teams and...

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$131K - $222K *

Drive impactful environmental solutions as a Principal Engineer/Scientist overseeing Massachusetts projects. Lead multi-disciplinary teams, engage clients, and ensure high-quality remediation practice...

Yesterday

  •   11 - 15 years exp.  •   Real Estate & Construction

$131K - $222K *

Lead Massachusetts projects as a Licensed Site Professional, managing site investigations and remediation efforts. Collaborate with multidisciplinary teams to execute effective environmental solutions...

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$120K - $145K *

Drive cutting-edge biocatalysis research and development for scalable API synthesis, integrating AI/ML tools and modern techniques while collaborating on innovative solutions for complex chemical synt...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the charge in developing innovative drug formulation solutions, overseeing project teams and driving new technology strategies to enhance pipeline progress and manufacturing processes for new med...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's advancing mRNA technology by leading process development and optimization for therapeutics and vaccines. Utilize your expertise to mentor others and drive project success in a colla...

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage complex R&D programs by overseeing operations, compliance, and reporting. Collaborate with diverse teams to achieve program goals, ensuring efficient execution and integration of scientific and...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Elevate your career by contributing to innovative proteomic workflows, enhancing sample preparation processes to support biomarker discovery. Collaborate across teams while applying advanced analytica...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $235K *

Lead the charge in developing non-clinical in vivo strategies, managing pre-clinical studies, and improving experimental models while driving innovation and collaboration across research teams to eval...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Transform complex systems by architecting AI-driven solutions that integrate cameras, edge devices, and cloud analytics. Analyze, model, and implement innovative frameworks while collaborating across...

Reposted 1 month ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $220K *

Champion innovative biotransformation strategies to enhance drug discovery and development. Drive metabolite profiling, oversee CRO studies, and collaborate with multidisciplinary teams to optimize ch...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $190K *

Champion drug discovery in neurobiology and metabolism, driving complex preclinical studies, leading cross-functional teams, and integrating mechanistic insights to tackle obesity and cardiometabolic...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Develop analytical control strategies for a clinical-stage small molecule program, leading method development and validation efforts while ensuring quality compliance, regulatory documentation, and ef...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $212K *

Transform drug discovery by leading computational strategies and optimizing novel therapeutics. Collaborate cross-functionally and drive innovative solutions to accelerate the advancement of impactful...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.