Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Senior Scientist II, Analytical Development
$110K - $140K *
Join a team that's shaping the future of mRNA analysis by developing innovative characterization methods for lipid nanoparticles. Collaborate across research to enhance the understanding and applicati...
2 weeks ago
Senior Scientist I/II - Early Analytical Development, Synthetic Molecules
$100K - $130K *
Accelerate scientific discoveries by applying your expertise in analytical methods to support innovative new synthetic modalities. Collaborate with cross-functional teams to drive projects from discov...
3 weeks ago
Senior Research Associate, Fermentation Development
$81K - $107K *
Partner with us to enhance microbial fermentation processes for recombinant proteins. This hands-on role emphasizes bench-scale bioreactor operations and data analysis in a fast-paced research environ...
1 week ago
$110K - $135K *
Join a team that's driving innovation in product development across diverse R&D projects. Collaborate with cross-functional teams to ensure timely execution, effective risk management, and alignment i...
5 days ago
$110K - $135K *
Optimize product launch processes by leading cross-functional projects, ensuring timely delivery while navigating risks and maintaining stakeholder alignment across diverse global teams...
5 days ago
$110K - $135K *
Take ownership of cross-functional NPI projects driving global product launches from inception to execution. Lead teams through project governance, risk management, and stakeholder alignment while ens...
5 days ago
Scientific Director - Synthetic Process Chemistry (Peptides & Small Molecules)
$148K - $257K *
Join a team that's shaping the future of peptide synthesis, driving innovative solutions and sustainability in drug development from bench-level research to commercial production, ensuring safe and ef...
1 week ago
Senior Scientist, Formulation and Delivery Sciences
$113K - $149K *
Advance the future of targeted therapeutics by leading innovative lipid nanoparticle research, focusing on formulation, delivery, and mechanistic challenges. Collaborate with a multidisciplinary team...
Today
Senior Scientist, Formulation and Delivery Sciences
$113K - $149K *
Join a team that's dedicated to advancing lipid nanoparticle formulations, targeting delivery strategies, and in vitro/in vivo performance assessments, collaborating with experts to overcome delivery...
Today
$70K - $95K *
Collaborate with teams to ensure product quality through comprehensive QA testing and analytical support. This role involves sample preparation, data analysis, and adherence to safety standards while...
2 weeks ago
Senior Software Engineer, Operations Research
$180K - $256K *
Join a team that's shaping the future of AI-driven scientific platforms. You’ll design, build, and optimize backend systems and data infrastructures, collaborating with experts to elevate orchestratio...
1 week ago
$90K - $120K *
Empower innovation in elastomer development as a senior technical leader, bridging material science and manufacturing processes for electrical safety products. Drive high-performance formulations whil...
3 weeks ago
Principal Applied Scientist, Console Science
$228K - $309K *
The Principal Applied Scientist will leverage a strong machine learning background to develop cutting-edge Conversational AI Systems, focusing on Natural Language Understanding and Generative AI. This...
Reposted today
$200K - $280K *
Architect strategies to unlock the potential of structured and unstructured data, guiding multiple software development teams in delivering quality solutions that meet mission-critical needs for gover...
3 weeks ago
Principal Scientist - HSV-1 Viral Vector Process Development
$160K - $210K *
Champion the development of a robust Analytical Development and QC function, drive regulatory readiness, and ensure operational excellence in a dynamic environment focusing on gene therapy programs an...
4 days ago
$70K - $95K *
Lead the charge in managing diverse projects from initiation to completion, ensuring they are delivered on time and within budget. Collaborate with team members and stakeholders to drive effective com...
2 weeks ago
$235K - $331K *
Pioneer the development of advanced ML models for lending and underwriting. Spearhead financial forecasting, leading a quantitative team to enhance valuation insights and market dynamics for collectib...
1 week ago
Particle and Powder Characterization Scientist
$70K - $95K *
Grow your career with a dynamic team focused on analyzing powder and liquid samples to determine their physical properties using advanced techniques and methodologies...
3 weeks ago
$235K - $331K *
Drive the development of quantitative models for lending & underwriting, enhancing financial forecasting and market dynamics analysis while leading a high-performing team to empower our growth within...
1 week ago
$164K - $238K *
Lead the charge in transformative Generative AI research, driving innovative technologies and collaborating with expert teams. Contribute to world-class publications while mentoring future talent, sha...
Reposted 3 weeks ago
Senior Scientist I Computational Chemistry
$120K - $150K *
Drive innovation in computational chemistry by leading the design and optimization of drug candidates, collaborating with cross-functional teams to enhance drug delivery strategies and advance first-i...
2 weeks ago
Pioneering Medicines: Principal Scientist / Associate Director, Analytical Development
$148K - $203K *
Join a team that's driving analytical excellence and regulatory compliance in biotech. Collaborate across functions to lead analytical development, QC oversight, and lifecycle management, enhancing pr...
2 weeks ago
Scientific & Technical Support Lead
$62K - $114K *
Join a team that's leading scientific and technical support for NOAA's NMFS. Engage with diverse stakeholders to assess marine resources and propose environmental solutions while overseeing critical c...
2 weeks ago
$120K - $150K *
Advance innovative solutions as a Senior Scientist, providing expert support to DARPA's Microsystems Technology Office through project management and strategic guidance on complex research initiatives...
3 weeks ago
Principal Scientist - In Vivo Expert, CVRI (Cardiovascular, Renal & Immunology)
$139K - $209K *
Lead the charge in advancing cardiovascular and renal research by leveraging your in vivo expertise. Collaborate with interdisciplinary teams to design experimental studies and drive innovation in dru...
1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.