Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$77K - $202K *

Analyze complex healthcare payer platform issues, manage workstreams, and mentor junior team members to enhance operational performance and member experiences using Epic software and industry best pra...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Join a team that's driving regional growth by leading sales strategies, developing partnerships, and expanding access to advanced imaging services. This high-impact role influences patient volume and...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive strategic growth initiatives by independently managing mid-market customer relationships and executing effective sales strategies to enhance retention and expansion across your portfolio of acco...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$134K - $160K *

Lead the charge in paid social strategy and performance for eCommerce brands. Drive measurable growth, mentor teams, and elevate operational standards while navigating complex client challenges with c...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform project delivery by leading cross-functional teams to ensure timely execution of Public Safety product implementations, enhancing client satisfaction and operational efficiency through exper...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$113K - $188K *

Pioneer a transformative Agile project management role overseeing large-scale software development. Lead coordination and execution across multiple teams and workstreams while ensuring alignment with...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Business Services

$145K - $190K *

Join a team that's dedicated to supporting educational institutions by providing expert legal counsel on governance, compliance, and operational matters. Collaborate with public entities to navigate c...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$200K - $260K *

Lead strategic partnerships to elevate and scale multi-year AI and LLM relationships. Collaborate cross-functionally to deepen alliances, drive integration optimizations, and advance collaborative opp...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Shape the future of client management by leading service teams on large accounts, enhancing carrier relationships, and developing strategic placement and renewal plans to drive success and improve pro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$124K - $165K *

Innovate the Federal and Defense marketing strategy by executing integrated, multi-channel programs that drive pipeline growth. Collaborate closely with sales leadership to engage diverse federal audi...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $175K *

Unlock potential by driving strategic growth and client relationships in a dynamic sales environment. Collaborate with teams to build a profitable book of business while consistently achieving sales t...

Today

  •   5 - 7 years exp.  •   Business Services

$117K - $161K *

Unlock potential by managing key customer relationships and driving growth across Soup, Italian, and Specialty Categories. Collaborate cross-functionally to achieve sales targets and execute strategic...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$117K - $161K *

Unlock potential by managing key customer relationships and driving growth across Soup, Italian, and Specialty Categories. Deliver on sales, profit, and share commitments through strategic planning an...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$95K - $115K *

Shape the future of economic strategy by leading impactful analyses and guiding clients through complex challenges in infrastructure, public policy, and investment. Collaborate with a diverse team to...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$150K - $180K *

Lead and coach a dynamic Production Print team, driving sales goals and developing talent. Collaborate with regional leaders to launch products and enhance technical sales support, ensuring excellence...

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $180K *

Lead legal initiatives within a dynamic team, managing complex transactions and advising on critical corporate matters. Collaborate across departments to ensure compliance and support strategic goals...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Join a dynamic team to enhance cloud security architecture, focusing on AWS and IAM. Leverage your expertise to shape security strategies, mentor engineers, and drive risk management initiatives in a...

Today

  •   Less than 5 years exp.  •   Staffing

$218K - $286K *

Empower your career as a Solutions Engineer, driving customer engagement and showcasing innovative technology. Collaborate with sales and technical teams to enhance market awareness and support enterp...

Today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$135K - $180K *

Lead strategic partnerships in healthcare, connecting brands with entertainment and sports. Collaborate with teams to develop, negotiate, and execute impactful initiatives that drive brand engagement...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$117K - $195K *

Advance your career as a Senior Information System Security Engineer, collaborating on critical national security projects. Drive cybersecurity initiatives, develop policies, and enhance cloud securit...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$170K - $210K *

Champion strategic growth by translating executive priorities into actionable plans. Collaborate across functions to drive performance, assess market opportunities, and ensure alignment on corporate o...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$76K - $121K *

Innovate in the design and development of cutting-edge biomedical devices. Collaborate with cross-functional teams to enhance patient care through advanced orthopedic solutions, ensuring compliance an...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $102K *

Lead strategic logistics and operations planning, managing development and execution of projects while analyzing capabilities and risks to ensure operational readiness and support for senior executive...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$121K - $182K *

Partner with us to lead complex cloud migrations, ensuring technical readiness and seamless execution across Azure and AWS environments while driving innovative solutions and high-quality outcomes in...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$154K - $232K *

Transform enterprise cloud strategies by leading large-scale migrations to Azure and AWS. Collaborate with global teams to establish architecture standards, ensure security, and drive innovative solut...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.