Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$95K - $115K *

Optimize pipeline integrity and reliability by leading maintenance, compliance, and project initiatives. Collaborate with operations and engineering teams to enhance safety and efficiency while ensuri...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $125K *

Drive operational excellence as you lead outbound shipping operations, ensuring timely and accurate order fulfillment while fostering a high-performing team in a dynamic manufacturing environment...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform the infrastructure landscape by leading Site Reliability Engineering and platform architecture for global expansion, ensuring reliability, cost efficiency, and compliance across multiple ser...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$163K - $375K *

Pioneer the discipline of Code Archaeology by owning methodologies, asset portfolios, and technical leadership. Drive evidence-first discovery, manage tooling, and represent the technical voice in cli...

1 week ago

  •   11 - 15 years exp.  •   Business Services

$150K - $375K *

Lead the charge in transforming enterprise software engineering through innovative Code Archaeology methodologies, asset portfolio ownership, and technical thought leadership, ensuring impactful moder...

1 week ago

  •   11 - 15 years exp.  •   Business Services

$165K - $210K *

Drive the technical vision for complex systems, leading cross-team initiatives and enhancing engineering standards. Own reliability and scalability of core infrastructure while mentoring engineers and...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Champion innovation by researching and implementing cutting-edge technology solutions that enhance efficiency and quality in manufacturing. Collaborate across teams to drive digital transformation and...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Elevate your career by providing actuarial expertise and strategic guidance on pricing and program structures for large accounts. Collaborate with leadership and stakeholders to drive profitability an...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K - $228K *

Lead the charge in shaping enterprise network architecture and modernization strategies. Provide technical guidance and design expertise to enhance security, scalability, and performance for a DoD age...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $228K *

Transform enterprise network architecture by providing strategic guidance and innovative design solutions. Lead a team in enhancing network security, scalability, and performance for a DoD agency's WA...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $134K *

Elevate compliance standards by conducting detailed FedRAMP assessments, analyzing technical artifacts, and collaborating with clients to ensure security controls are effectively implemented and docum...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$152K - $190K *

Elevate quality assurance within AI solutions by leading test efforts, validating products, and enhancing automated frameworks to deliver reliable, compliant, and high-performing technology that meets...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$104K - $166K *

Join a team that's dedicated to enhancing cybersecurity operations by monitoring, analyzing, and responding to security incidents. Leverage your expertise to protect critical systems and mentor junior...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$106K - $114K *

Lead the charge in driving strategic partnerships, managing budgets, and optimizing performance. Collaborate cross-functionally to enhance partner success and deliver impactful training programs, ensu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$56K - $105K *

Transform electronic fabrication processes by evaluating, optimizing, and documenting assembly techniques. Collaborate with engineers and operators to ensure quality and efficiency in soldering, harne...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$171K - $248K *

Lead a dynamic engineering team to enhance infrastructure and networking, driving user-focused product development while fostering collaboration and operational excellence across the organization...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$80K - $95K *

Engineer innovative electrical systems and components, ensuring compliance with standards while collaborating with cross-functional teams to enhance product performance and reliability...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $200K *

Develop and maintain robust data pipelines and models, collaborating with cross-functional teams to enhance data practices and ensure quality. Drive modernization efforts in data engineering, optimizi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Drive client success by managing relationships, enhancing satisfaction, and identifying growth opportunities. Collaborate with internal teams to deliver exceptional service and exceed client expectati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $222K *

Drive clinical adoption and enhance partnerships by leading a high-performing Medical Science Liaison team. Collaborate with sales and medical teams to educate stakeholders, influence decision-making...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Explore the dynamic role of a Program Manager, overseeing end-to-end data collection programs. Drive operational excellence, client satisfaction, and strategic execution in a fast-paced environment, e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Lead the charge in transforming agency operations by ensuring seamless onboarding and mastery of our all-in-one AdTech platform, bridging technical capabilities with real-world execution for impactful...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$194K - $266K *

Lead the charge in driving commercial growth by securing high-value partnerships and expanding market presence. Mentor a dynamic team while executing strategic initiatives that enhance client relation...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.