Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$167K - $300K *

Lead the charge in oncology marketing by developing KOL engagement strategies and insights for individualized therapies. Collaborate cross-functionally to drive brand strategy and launch planning, ens...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$79K - $112K *

Transform cash forecasting processes by leveraging technology and analytics. Collaborate with Treasury leadership to enhance cash flow insights and automate reporting, ensuring accuracy and efficiency...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$114K - $121K *

Lead a skilled team in executing complex turbine maintenance across North America. Ensure safety, quality, and efficiency while mentoring technicians and managing logistics. This role requires signifi...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$87K - $121K *

Champion clinical excellence by leading a dedicated nursing team in providing high-quality care to medically fragile pediatric patients. Engage in meaningful relationships while ensuring effective com...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic dental team to provide comprehensive care, diagnose conditions, and implement tailored treatment plans. Collaborate with specialists and maintain high standards of patient satisfaction...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$127K - $171K *

Lead a dynamic team in overseeing compliance and supervision for securities and investment advisers. Drive risk mitigation strategies, enhance supervisory frameworks, and collaborate with cross-functi...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$137K - $185K *

Drive the execution of complex projects, ensuring alignment across global teams. Collaborate with stakeholders to manage risks, track progress, and deliver key medical strategies while fostering cross...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock product potential by leading the development of innovative food safety solutions. Collaborate with cross-functional teams to address complex industry challenges and drive scalable product strat...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Shape the future of marketing by leading strategy and execution in a dynamic B2B SaaS environment. Collaborate closely with leadership to drive pipeline growth and create compelling narratives that re...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Shape the future of financial technology by leading a dynamic team in developing innovative cloud-based applications. Leverage your extensive software development expertise to deliver high-quality sol...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$115K - $192K *

Elevate operational excellence by leading process design and transformation initiatives. Drive automation, quality management, and continuous improvement to enhance client data operations and ensure s...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$66K - $189K *

Innovate analytical strategies to enhance toxicology assessments, ensuring compliance and data integrity. Collaborate across teams to drive project success and influence decision-making through advanc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$81K - $122K *

Transform fleet operations by leading a dynamic dispatch team, ensuring exceptional service delivery and operational excellence while fostering team development and customer satisfaction in a fast-pac...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Transportation

$140K - $180K *

Shape the future of our iOS platform by designing and implementing scalable features. Collaborate with cross-functional teams to deliver innovative solutions that enhance client interactions with emis...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$148K - $233K *

Engage with US mortgage lenders to drive adoption of FICO's credit analytics and services. Lead initiatives to maximize revenue opportunities and enhance client experiences while providing strategic i...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Join a dynamic team to drive technical success and adoption across enterprise accounts. Leverage your expertise in project management and technical execution to enhance deployment health and fuel acco...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Lead the charge in project controls management, ensuring effective cost, schedule, and risk oversight across diverse programs. Collaborate with teams to deliver actionable insights that drive successf...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$75K - $107K *

Drive strategic customer relationships and revenue growth for complex Public Sector and Education accounts, managing renewals, retention, and expansion opportunities while navigating intricate procure...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $107K *

Elevate customer relationships and drive revenue growth by managing complex Federal accounts. Collaborate with cross-functional teams to align strategies with customer needs, ensuring retention and ex...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead cross-functional teams to enhance the Epic Resolute Hospital Billing application, ensuring project milestones are met while driving process improvements and delivering exceptional service to inte...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $165K *

Engage with clients to assess technical needs and demonstrate how our solutions meet their requirements. Collaborate with sales teams to secure wins, conduct demos, and build lasting relationships wit...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform claims management by leading strategic initiatives, overseeing operations, and driving continuous improvement across a diverse portfolio, ensuring optimal outcomes and compliance while colla...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Champion strategic client relationships by managing complex commercial accounts, evaluating risks, and coordinating multidisciplinary teams to exceed service standards and deliver exceptional results...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Analyze provider network data to ensure accuracy and compliance. Collaborate with teams to maintain critical information, generate reports, and support quality improvement initiatives in provider admi...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Empower your career by serving as a legal partner in procurement and supply chain, providing expert guidance and support in contract negotiation, vendor relations, and operational risk management acro...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.