Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$108K - $180K *

Join us in leading product strategy and execution for a diverse portfolio, enhancing Provider Contracting and Credentialing. Collaborate with cross-functional teams to drive innovation, improve custom...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Join a team that's dedicated to supporting adults with serious mental illnesses. Lead a multi-disciplinary ACT team, providing comprehensive assessments, medication management, and therapeutic support...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $338K *

Champion DMPK project leadership by ensuring high-quality data delivery and supporting drug candidate progression through innovative modeling and cross-functional collaboration in a dynamic biotech en...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Unlock potential by engaging in diverse engineering projects, analyzing data, and supporting operational functions. Collaborate with teams to enhance methods and ensure safety while gaining valuable e...

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$75K - $95K *

Unlock potential by managing Genesys Cloud configurations and ensuring system integrity. Collaborate with teams to implement changes, troubleshoot issues, and maintain documentation for optimal contac...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Transportation

$95K - $115K *

Drive innovation in machine design by developing concepts, performing analyses, and guiding projects from inception to installation. Collaborate with cross-functional teams to ensure manufacturable, r...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$240K - $290K *

Elevate your career by leading a dynamic engineering team focused on production and infrastructure. Drive performance, foster collaboration, and deliver innovative solutions while managing diverse tec...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$154K - $242K *

Champion operational excellence by leading global tax provisions and compliance. Collaborate with cross-functional teams to enhance processes, mentor talent, and drive strategic tax initiatives while...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$82K - $150K *

Accelerate growth by driving new customer acquisition and expanding market share within the dental implant community. Leverage a hunter mentality to convert competitive accounts and position value-ori...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Transform data operations by leading our Snowflake platform migration, ensuring security, reliability, and cost efficiency while collaborating across teams to standardize practices and enhance data ma...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$132K - $176K *

Pioneer innovative strategies to drive product demand in the Rheumatology sector. Build strong relationships with healthcare professionals and enhance patient experiences through effective communicati...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $157K *

Join our dynamic team to design and enhance a web portal application, improving user experience and functionality. Collaborate with engineers and product managers to deliver impactful solutions that s...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $99K *

Elevate production efficiency by overseeing first line management functions, driving continuous improvement initiatives, and ensuring safety and quality in manufacturing operations for pet food. Colla...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$130K - $150K *

Optimize IT operations by managing systems, enhancing security, and leading projects. Ensure seamless network infrastructure and provide technical support while coordinating with vendors and maintaini...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Deliver comprehensive project management for complex electromechanical systems in hydropower plants, ensuring profitability, compliance, and customer satisfaction through effective leadership and inte...

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Pioneer advanced oncology care by joining a dedicated team of APPs, providing 24/7 support for patients with hematological malignancies. Collaborate with specialists in a dynamic environment focused o...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $155K *

Shape the future of data and AI solutions by driving product success, collaborating with cross-functional teams to align business goals with innovative platforms and ensuring continuous improvement th...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$60K - $135K *

Empower a Scrum team by facilitating processes, removing impediments, and ensuring adherence to Agile methodologies. Foster collaboration and self-management to achieve sprint goals and enhance team p...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $153K *

Transform financial management practices by leading budgeting, forecasting, and resource allocation efforts. Collaborate with teams to enhance decision-making and optimize financial systems, ensuring...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $165K *

Drive product strategy and roadmap for spectroscopy technologies, integrating analytical solutions into bioprocessing systems. Collaborate with cross-functional teams to define product needs and enhan...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $275K *

Lead the charge in building and scaling a dynamic partner program, driving revenue through strategic alliances and co-selling. Collaborate cross-functionally to establish processes and integrations, e...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Champion product excellence by owning the vision, backlog, and delivery outcomes. Collaborate with stakeholders and technical teams to ensure solutions align with business goals and regulatory standar...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$57K - $124K *

Join us in driving credit decisions and portfolio management in Equipment Finance. You'll analyze financial data, prepare documentation, and collaborate with sales and credit teams to ensure underwrit...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in enhancing client relationships and driving value realization for managed services. Oversee client success strategies, retention, and growth while collaborating cross-functionally to...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$118K - $196K *

Transform public health analytics by leading AI development and deployment. Guide multidisciplinary teams to create scalable solutions, ensuring compliance and quality while driving innovation and col...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.