Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$250K - $300K *

Join a dynamic team of board-certified dermatologists and Mohs surgeons, delivering exceptional patient care across multiple states. Contribute to a leading dermatology practice focused on innovation...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $193K *

Lead the charge in enhancing power system reliability through expert protection engineering. Collaborate with clients, innovate solutions, and support cutting-edge technologies for safe, efficient pow...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Empower innovative research in immunology and tumor biology, focusing on brain cancers. Develop collaborative programs and novel therapies, while mentoring students and contributing to the academic co...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$105K - $207K *

Unlock the potential of quality assurance by leading innovative testing solutions, interfacing with clients, and driving excellence in technology delivery across diverse environments and platforms...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$105K - $207K *

Join a team that's transforming technology through innovative QA solutions. Leverage your expertise to enhance client success by leading testing strategies and ensuring quality across diverse platform...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $150K *

Shape the future of robotics and automation by validating cutting-edge technologies. Collaborate with multidisciplinary teams to solve complex challenges and ensure product excellence from prototype t...

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Elevate your career by managing and optimizing multi-platform paid social campaigns. Leverage data-driven insights to enhance client ROI while collaborating with creative teams and leading strategic i...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$95K - $184K *

Optimize sales performance by developing a high-performing team, driving market growth, and ensuring compliance with ethical and legal standards while adhering to company policies...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the charge in optimizing laboratory operations by managing personnel, ensuring compliance, and implementing quality programs. Collaborate with healthcare teams to enhance service delivery and int...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $250K *

Unlock potential by joining a dynamic sales team focused on roofing and home improvement. Enjoy uncapped commissions, comprehensive training, and a clear path for advancement while making a significan...

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$87K - $157K *

Lead the charge in transforming healthcare data solutions by leveraging advanced SQL, Snowflake, and SAS expertise. Collaborate with cross-functional teams to enhance business processes and ensure com...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$118K - $178K *

Shape the future of enterprise AI by designing and enhancing scalable platforms. Collaborate with cross-functional teams to deliver secure, reliable solutions while driving operational excellence and...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$132K - $165K *

Transform user experiences by crafting streamlined flows, building robust APIs, and integrating third-party software. Collaborate with a dynamic team to deliver elegant solutions while advocating for...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$204K - $290K *

Lead the charge in creating seamless cardholder experiences by driving technical strategy, collaborating across teams, and fostering a culture of quality and ownership in a dynamic, AI-driven environm...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $149K *

Analyze and enhance IT infrastructure through secure cloud solutions, ensuring 24x7 availability. Collaborate with teams to streamline workflows, improve system reliability, and tackle complex challen...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Drive the evolution of LNG technical frameworks, ensuring alignment across engineering, commercial, and supplier teams. Enhance project execution and customer contracts while maintaining clarity and c...

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$250K - $250K+*

Support research initiatives by engaging in human subject activities, data collection, and regulatory submissions. Collaborate with study teams to enhance clinical research efforts and develop essenti...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Deliver impactful project management by co-managing resources, schedules, and risks. Ensure compliance and alignment with strategic goals while utilizing reporting tools to track performance and drive...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$118K - $178K *

Join a team that's driving growth through consultative sales in clinical research. Collaborate with pharmaceutical and biotech leaders to enhance global health by advancing life-changing therapies thr...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Help us modernize complex legacy applications by designing, developing, and implementing scalable solutions. Collaborate with cross-functional teams to enhance system performance, security, and reliab...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Oversee a team of Field Automation Technicians, ensuring the installation, maintenance, and troubleshooting of automated systems meet operational and safety standards across various locations...

2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$78K - $119K *

Lead the charge in managing operations for a state agency, overseeing procurement, facilities, and safety programs. Drive team performance and ensure compliance across multiple locations while support...

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$101K - $169K *

Optimize North American sales processes and systems to enhance efficiency, drive adoption, and improve outcomes. Collaborate with teams to identify issues, implement solutions, and ensure consistent u...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Transportation

$80K - $95K *

Grow your career by enhancing manufacturing processes while ensuring quality and safety. Drive continuous improvement in production efficiency and lead training initiatives to empower team members at...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$69K - $104K *

Shape the future of environmental protection by managing air emission testing activities, evaluating scientific data, and ensuring compliance with regulations. Collaborate with stakeholders to enhance...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.