Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Controls Engineer - Lifecycle Services
$68K - $187K *
Support and enhance client systems by providing technical expertise, leading installations, and troubleshooting mechanical and electrical equipment. Collaborate with teams for continuous improvement a...
3 weeks ago
Principal Product Builder, Data
$205K - $256K *
Transform your career by leading Apollo's data strategy, ensuring the highest quality B2B data for GTM success. Drive product vision, collaborate cross-functionally, and enhance customer experiences t...
1 week ago
$80K - $95K *
Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...
2 weeks ago
Director of Engineering, Cyber GRC Data, AI & Automation
$160K - $210K *
Lead the charge in transforming Cyber Governance, Risk & Compliance through innovative data, AI, and automation strategies. Drive measurable outcomes and modernize technology platforms while building...
Yesterday
Manager, Security Operations Center
$110K - $130K *
Take ownership of a 24x7 Security Operations Center, leading a team of SOC analysts. Drive performance, manage client relationships, and ensure high-quality investigations while fostering team develop...
Today
Senior Principal, Business Management - Debt
$300K - $500K *
Lead and optimize a diverse portfolio of debt mandates, driving execution from initial offer to close. Collaborate across teams to enhance transaction velocity and deliver innovative capital solutions...
3 weeks ago
Cardiovascular Vice President - Central Zone
$159K - $218K *
Advance your career by leading a dynamic sales team to drive growth in cardiovascular imaging. Shape strategies, enhance customer satisfaction, and achieve financial goals while making a significant i...
2 weeks ago
Assoc Dir, Neuro Thought Leader Liaison (South region)
$190K - $225K *
Shape the future of healthcare by driving strategic KOL engagement and insight generation in rare neurology. Collaborate with thought leaders to influence brand strategy and enhance patient outcomes t...
1 month ago
Client Growth & Success, Senior Manager- Enterprise Accounts
$130K - $145K *
Champion client success by managing strategic partnerships with mid-sized enterprises. Drive measurable outcomes through relationship management, consultative problem-solving, and cross-functional col...
1 week ago
Senior Technical Account Manager
$110K - $130K *
Join a team that's dedicated to enhancing customer success through expert guidance in Privilege Access Management. Leverage your technical skills to support enterprise clients, ensuring seamless deplo...
3 weeks ago
Senior Technical Project Manager - Software Development
$138K - $180K *
Shape the future of medical device development by driving project execution, collaboration, and innovation within a dynamic Research & Development team focused on enhancing healthcare outcomes and pat...
Reposted 5 days ago
Sr. Director, Sales Systems & Processes
$198K - $298K *
Champion the optimization of Sales systems and processes, driving productivity and strategic initiatives. Collaborate with cross-functional teams to enhance the sales experience and lead a global team...
2 weeks ago
Solution Engineering Manager (Specialty Sales)
$120K - $165K *
Pioneer in leading a dynamic team of Solution Engineers, optimizing multi-discipline datacenter solutions across data protection, storage, compute, and networking. Drive collaboration to shape industr...
1 month ago
$110K - $130K *
Transform financial operations by leading accounting, reporting, and compliance efforts. Collaborate with teams to ensure integrity in financial data and support strategic growth initiatives while fos...
3 weeks ago
Vice President Human Resources
$200K - $250K *
Unlock potential by leading HR strategies across 12 manufacturing sites and a remote workforce. Drive high-volume hiring, simplify processes, and foster a proactive culture to support rapid growth and...
2 weeks ago
$95K - $115K *
Lead and enhance day-to-day accounting operations, focusing on accounts payable, receivable, and cash management. Collaborate with cross-functional teams to ensure accurate, timely transactions while...
1 week ago
RCM Implementation Consultant - EHR/SaaS/Healthcare IT/PT
$80K - $95K *
Manage the implementation process for clients in Revenue Cycle Management, ensuring efficient setup and optimization of billing workflows. Serve as the primary expert, guiding healthcare organizations...
1 week ago
Identity Operations Service Lead
$162K - $292K *
Join a team that's redefining identity operations by leading a 24/7 team to enhance access management strategies. You'll shape the vision, drive process innovation, and foster talent in a collaborativ...
Reposted 6 days ago
$156K - $214K *
Inspire growth by leading an Enterprise CPG sales team, driving strategic partnerships with top-tier brands, and influencing C-suite executives to leverage innovative insights for impactful decisions...
Today
$79K - $127K *
Unlock insights into medical cost trends by leveraging data analytics. Collaborate with cross-functional teams to develop strategic recommendations, track program outcomes, and present findings clearl...
6 days ago
$90K - $95K *
Take ownership of high-volume revenue accounting, ensuring compliance with ASC 606. Lead technical execution, data analytics, and financial systems design while providing training and insights to enha...
3 weeks ago
$105K - $150K *
The Senior Consultant, NetSuite is responsible for leading full-cycle NetSuite implementation projects, from discovery to deployment, while ensuring excellent customer service. This role involves coll...
Reposted 3 weeks ago
Senior Manager, Global Regulatory Process and Compliance
$139K - $184K *
Lead regulatory compliance programs ensuring inspection readiness and proactive risk management across cross-functional teams. Monitor compliance health, manage data quality, and drive improvements al...
Reposted 2 weeks ago
$100K - $130K *
Partner with us to deliver strategic financial insights that drive business success through effective forecasting, budgeting, and performance analysis, enabling informed decision-making and enhancing...
Reposted 1 week ago
Associate Principal Solution Architect
$177K - $279K *
Unlock potential by architecting customized applications using Conga Products. Lead end-to-end Quote-to-Cash implementations, enhancing operational efficiency and driving business transformation in co...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.