Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$80K - $95K *
Join a team that's shaping the future of utility-scale transmission projects. Oversee contractor activities, ensure quality installations, and foster strong relationships while managing project logist...
3 days ago
Sr. Manager, Commercial Systems - Salesforce (REMOTE)
$110K - $130K *
Innovate commercial systems to enhance revenue operations, integrating tools like Salesforce and AI for streamlined workflows. Collaborate across teams to ensure data integrity and optimize processes...
2 weeks ago
Senior Product Manager, Enterprise Solutions
$174K - $218K *
Reimagine healthcare by shaping partnerships that drive innovative virtual-first care solutions. As a Senior Product Manager, you will bridge product and commercial teams, enhancing member engagement...
Reposted 4 weeks ago
$180K - $210K *
Join a team that's redefining IT leadership by overseeing strategic operations, enhancing service delivery, and ensuring compliance. Drive innovation and efficiency while aligning IT with business goa...
Today
Sr Channel Account Manager, Managed Service Providers (Remote US)
$184K - $287K *
Empower our channel sales strategy by building and scaling MSP partnerships, driving recurring revenue, and collaborating cross-functionally to establish a robust partner ecosystem that thrives in the...
2 weeks ago
Director of Consultant Relations
$110K - $130K *
Unlock potential by cultivating strategic relationships with benefits consultants and brokers. Drive revenue growth through effective partnerships, collaboration with cross-functional teams, and exper...
2 weeks ago
Director, CRM Product Management
$150K - $180K *
Accelerate your career by leading CRM product management, shaping the roadmap for Salesforce solutions, and driving innovation in AI integration while collaborating with cross-functional teams to enha...
2 weeks ago
Long Term Care Actuary, Controllership Oversight
$110K - $130K *
Drive governance and controllership for LTC actuarial models, ensuring compliance and effective controls. Collaborate with cross-functional teams to enhance processes and documentation, supporting mod...
2 weeks ago
Senior Program Director, Transportation Engineering
$157K - $283K *
Join a team that's driving growth in Texas transportation design services. Leverage your engineering and management expertise to enhance community projects, lead interdisciplinary teams, and build str...
2 weeks ago
$90K - $110K *
Transform healthcare delivery by leading clinical operations, ensuring high-quality patient care, and fostering collaboration across departments. Drive strategic initiatives while managing resources a...
3 weeks ago
$110K - $130K *
Join a team that's driving strategic growth through partnerships with GSIs, MSPs, and VARs. This role combines relationship building, market strategy, and sales leadership to generate revenue and opti...
Reposted 2 weeks ago
Director, Sales Engineering (Presales) - Retirement & Pension
$165K - $195K *
Transform enterprise sales and modernization for retirement technology. Lead a team of Sales Engineers, engaging with diverse stakeholders to deliver tailored solutions and drive impactful customer ex...
1 week ago
$119K - $179K *
Lead the charge in architecting FHIR-compliant data models to enhance clinical data integration and usability, supporting patient care and research initiatives across the organization...
3 weeks ago
Director, Franchise Operations - South
$145K - $169K *
Transform the South Zone's beverage landscape by driving strategic growth, aligning stakeholders, and executing innovative plans that enhance market performance and profitability across a diverse Coca...
Today
Director, Proactive Defense Operations
$168K - $281K *
Lead the charge in Proactive Defense Operations, transforming threat data into automated defenses. Drive strategy, team performance, and operational excellence while collaborating across functions to...
Today
$100K - $120K *
Lead the charge in transforming IT support for healthcare centers by evaluating, planning, and executing transitions to AMSURG Managed IT Services, while architecting cloud solutions with Microsoft 36...
2 weeks ago
Counsel - Commercial Transactions
$132K - $221K *
Drive enterprise-wide legal support for global contracting activities, focusing on procurement and technology transactions. Collaborate with cross-functional teams to manage risks and ensure complianc...
2 weeks ago
Technology FinOps Lead / Manager
$114K - $158K *
Drive financial excellence by leading integrated management of Technology spend, enhancing visibility, and optimizing costs through collaboration with cross-functional teams to improve processes and d...
Today
Quality Control, Validation Lead
$110K - $130K *
Join a team that's shaping the future of Quality Control laboratories by providing technical oversight for startup, validation, and compliance across multiple manufacturing sites, ensuring operational...
2 weeks ago
Financial Improvement & Audit Remediation Specialist
$89K - $148K *
Elevate financial management and audit remediation efforts for DoD clients, leveraging expertise in accounting, internal controls, and compliance to drive strategic improvements and ensure adherence t...
1 week ago
Diagnosis-Related Group (DRG) Auditor III
$73K - $98K *
Join a team that's dedicated to excellence in DRG auditing. Leverage your expertise in MS-DRG and APR-DRG coding to ensure accuracy and compliance while working remotely. Enjoy a collaborative environ...
Today
$140K - $185K *
Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...
Reposted 3 weeks ago
$170K - $200K *
Elevate tax administration services for exchange-traded funds by leading a dynamic team, resolving complex tax matters, and enhancing processes to support a growing fund platform while ensuring compli...
2 weeks ago
Corporate Development Director
$180K - $300K *
Join a team that's driving corporate development initiatives, managing M&A processes, and collaborating with leadership to identify and execute strategic acquisitions that enhance growth and innovatio...
3 weeks ago
$110K - $199K *
Develop and maintain scalable data pipelines, leveraging Snowflake and cloud tools to enhance data quality and accessibility. Mentor a growing team while driving best practices in data engineering and...
Reposted 3 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.