Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Revenue Cycle Jobs in South Dakota

Sort By: Relevance

$110K - $130K *

Drive patient access to Provenge by removing reimbursement barriers and collaborating with healthcare stakeholders. Develop strategies to enhance business growth while navigating complex payer policie...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by providing clinical and administrative leadership to enhance patient care standards. Collaborate with medical staff and departments to ensure compliance and drive strategic initiati...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Explore opportunities to partner with engineers and stakeholders, translating technical discussions into actionable deliverables while supporting CI/CD initiatives and repository governance with a foc...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$145K - $165K *

Champion revenue growth by building partnerships with city officials and transport operators. Navigate complex sales cycles, execute market plans, and provide strategic insights for sustainable public...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$135K - $155K *

Drive impactful data solutions by bridging business needs with engineering teams. Own project intake, prioritize requests, and ensure clear communication across departments to enhance efficiency and d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $200K *

Elevate your career by joining a dynamic team focused on transforming corporate learning. As a senior leader, you'll drive strategic initiatives, engage with top executives, and shape the future of wo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$141K - $212K *

Deliver strategic oversight and operational management for FDA-mandated REMS programs, ensuring compliance, governance, and collaboration across teams and vendors to enhance program effectiveness and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Transform your career by leading GTM enablement initiatives that equip sales and marketing teams with essential training, certifications, and resources to drive success in a rapidly scaling organizati...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$150K - $190K *

Lead the charge in shaping data platform strategies and governance, driving innovative solutions and team development. Collaborate with partners to enhance AI readiness and ensure successful technical...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Take ownership of financial planning and analysis efforts, driving insights and process improvements to enhance business performance as we support a rapidly growing, innovative dental technology compa...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Drive your career with a team leading customer renewals. Manage a skilled group focused on achieving retention targets, effective negotiations, and proactive customer engagement, all while collaborati...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$180K - $220K *

Champion clinical services initiatives, driving strategic content development and mentoring teams to enhance market access and client success. Lead projects, ensure compliance with standards, and reso...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $176K *

Lead the charge in managing a high-performing PMO team, driving project success through strategic financial oversight, talent development, and cross-functional collaboration to enhance operational eff...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $140K *

Accelerate your career by driving new business growth and managing enterprise client relationships. Leverage your expertise in managed sales solutions to exceed targets and optimize sales processes in...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$250K - $300K *

Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$176K - $293K *

Develop and implement strategic account plans to drive sales growth and build relationships with key decision-makers in healthcare. Collaborate with cross-functional teams to achieve business goals an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$102K - $120K *

Join a team that's transforming healthcare analytics by bridging complex data with strategic insights. Leverage your SQL expertise and analytics engineering skills to empower stakeholders and drive va...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$163K - $220K *

Shape the future of healthcare by leading analytics for managed care, driving payer strategies, and delivering insights to enhance access to medical benefit products. Collaborate with cross-functional...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $155K *

Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $150K *

Unlock potential by leading claims adjudication logic to enhance accuracy and efficiency. Drive strategic improvements, collaborate across teams, and ensure compliance while optimizing operations in a...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$96K - $118K *

Join a dynamic team to develop and manage supply chain contracting strategies that optimize costs and enhance value for member pharmacies. This role involves supplier negotiations, category performanc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $149K *

Lead the charge in delivering complex product development projects by managing cross-functional teams, ensuring customer satisfaction, and driving operational excellence from initiation to delivery in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Drive operational excellence by leading global partnerships and enhancing efficiency. Collaborate with teams to achieve strategic goals, support change management, and ensure accountability in meeting...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$156K - $235K *

Accelerate your career by leading Theranostics initiatives within a national healthcare advisory team. Collaborate with executives to enhance patient outcomes and operational performance through strat...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$130K - $160K *

Transform the planning landscape by leading integrated sales and operations processes. Drive cross-functional collaboration, develop robust planning models, and ensure alignment on business objectives...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.