Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Revenue Cycle Jobs in South Dakota

Sort By: Relevance

$108K - $196K *

Shape the future of healthcare by managing client relationships and optimizing clinical programs. Collaborate with teams to drive client success and ensure alignment with company goals, leveraging dat...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$143K - $214K *

Help us drive strategic value by transforming enterprise operations through innovative Workday solutions. Leverage your consulting expertise to foster relationships, align with partners, and lead impa...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$109K - $136K *

Drive accurate, evidence-based clinical claims while collaborating with Marketing, Legal, and Clinical teams. Build and manage the claims framework and evidence library to support bold, compliant mark...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $220K *

Drive innovation in actuarial functions by leveraging AI and advanced analytics. Lead high-impact initiatives that transform insights into actionable business strategies, enhancing decision-making and...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $250K *

Unlock potential by leading innovative clinical documentation initiatives that enhance quality, compliance, and revenue cycle outcomes. Collaborate with cross-functional teams to redefine workflows an...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K *

Lead the charge in auditing inpatient claims, ensuring coding accuracy and clinical validation. Utilize advanced coding expertise to analyze claims independently, while meeting productivity and qualit...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$103K - $192K *

Shape the future of healthcare reimbursement by leading analytics for payor contracting and out-of-network strategies. Collaborate with cross-functional teams to optimize financial outcomes and drive...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Unlock potential by driving sales and education in oncology medical devices. Collaborate with healthcare professionals to enhance treatment options for liver and pancreatic cancer while achieving regi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Optimize operations in high-volume e-commerce fulfillment centers by leading teams, validating system capabilities, and establishing efficient workflows to drive scalable and successful launch initiat...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$162K - $244K *

Shape the future of cloud architecture by leading diverse teams, driving Azure modernization, and connecting business objectives with innovative solutions. As a technical leader, you will foster inclu...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

$160K - $200K *

Lead the charge in financial strategy and operational excellence, driving growth and sustainability for a mission-driven organization. Collaborate with leadership to implement innovative solutions and...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$101K - $152K *

Unlock your potential by supporting reimbursement operations and strategic initiatives that enhance patient access across diverse therapies. Collaborate with cross-functional teams to drive process im...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $110K *

Unlock potential by leading revenue recognition and compliance efforts, ensuring adherence to ASC 606 and GAAP standards. Collaborate with cross-functional teams to optimize revenue processes and enha...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$115K - $130K *

Champion executive compensation strategies by managing program administration, collaborating with HR partners, and conducting market research to enhance compensation practices and support organization...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $205K *

Optimize marketing operations by managing systems, data, and processes to drive pipeline growth. Lead HubSpot and Salesforce integration, oversee lifecycle reporting, and implement AI solutions while...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$149K - $299K *

Champion exceptional service delivery by leading Help Desk operations, ensuring high-quality support for members and stakeholders. Drive continuous improvement, operational excellence, and effective i...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Drive financial excellence by integrating and analyzing revenue and expense forecasts, ensuring alignment across functions. Collaborate with FP&A teams to deliver actionable insights and support strat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$159K - $218K *

Transform sales performance by leading a dynamic team to exceed revenue goals across diverse laboratory solutions in a defined region, fostering customer relationships and driving strategic initiative...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Partner with us to drive growth in mid-tier accounts, enhancing revenue retention through upselling and collaboration. Lead strategic conversations, manage expansion pipelines, and ensure client succe...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $160K *

Drive client success in our lab network by managing relationships, ensuring renewals, and identifying growth opportunities. Collaborate across teams to enhance processes and improve client experiences...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Engage with us to drive innovative solutions in the healthcare supply chain. Collaborate closely with diverse teams, tackle complex challenges, and enhance patient care through strategic insights and...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$116K - $145K *

Unlock potential by leading payer negotiations and expanding access across commercial, Medicare, and Medicaid sectors. Drive strategic partnerships and ensure compliance while maximizing patient acces...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.