Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$170K - $200K *

Drive strategic business development initiatives to enhance R&D and commercial growth. Collaborate with cross-functional teams to assess opportunities, negotiate deals, and present findings to senior...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$108K - $184K *

Transform the Provider Network operations by leading strategic initiatives, enhancing provider relations, and ensuring compliance across multiple lines of business. Drive performance and collaboration...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $184K *

Accelerate progress at a leading healthcare provider network by overseeing operations, enhancing provider relations, and ensuring compliance across multiple lines of business. Drive strategic initiati...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $184K *

Join a team that's redefining healthcare provider network operations. Oversee strategic initiatives across multiple divisions, ensuring compliance and operational excellence while enhancing provider r...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $184K *

Transform the future of healthcare provider networks by leading operational excellence, strategic initiatives, and cross-departmental collaboration to enhance provider relations and data management ac...

Georgia, USRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $184K *

Lead the charge in optimizing Provider Network operations, overseeing key functions like Provider Relations and Credentialing. Drive strategic initiatives to enhance performance across Medicaid, Medic...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Advance your career by leading the development of integrated global manufacturing network strategies. Collaborate across functions to ensure supply continuity and operational performance while driving...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Transform global manufacturing strategies by integrating portfolio growth, demand, and operational performance. Collaborate across functions to develop robust network scenarios and ensure supply conti...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in developing integrated network strategies for global manufacturing. Collaborate across functions to optimize capacity, sourcing, and site planning, ensuring alignment with long-term...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $215K *

Drive impactful results by leading cross-functional teams and executing strategic initiatives that enhance organizational effectiveness and drive growth. Collaborate with stakeholders to innovate solu...

4 weeks ago

  •   Less than 5 years exp.  •   Media

$90K - $215K *

Advance the strategic vision by managing cross-functional teams to deliver innovative solutions, ensuring alignment with business objectives and driving continuous improvement across projects...

4 weeks ago

  •   Less than 5 years exp.  •   Media

$160K - $200K *

Champion the future of mental health care by leading a dedicated team, ensuring quality standards, and enhancing patient outcomes through innovative practices and collaborative efforts in a community...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $160K *

Take ownership of the medical staff services department, ensuring compliance, education, and operational excellence while fostering collaboration between medical and executive leadership to enhance pa...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$147K - $187K *

Lead the charge in delivering exceptional nursing care by managing clinical operations, fostering staff development, and ensuring compliance with healthcare standards while enhancing patient experienc...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in delivering exceptional home health services by supervising patient care, managing interdisciplinary teams, and ensuring compliance with regulatory standards while fostering a suppor...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$147K - $187K *

Unlock potential by leading clinical operations and fostering excellence in patient care. As a key manager, you'll drive staff development, enhance patient experiences, and ensure compliance with heal...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Manage a team to optimize revenue cycle operations, ensuring client satisfaction and performance excellence. Drive continuous improvement initiatives while overseeing accounts receivable functions for...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Champion operational excellence by leading a team to optimize revenue cycle results, ensuring client satisfaction and compliance while fostering a culture of continuous improvement and innovation acro...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$96K - $106K *

Advance comprehensive behavioral health services by leading clinical assessments, ensuring fidelity to evidence-based practices, and providing supervision to interns and staff, while fostering interdi...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $220K *

Champion strategic business operations by driving analysis, planning, and board preparation. Collaborate with Finance, Product, and Engineering to influence pricing and revenue decisions that propel c...

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $220K *

Accelerate progress at a dynamic startup by driving strategic business operations and planning. Lead decision-making on pricing, economics, and board preparation directly influencing capital allocatio...

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $220K *

Shape strategic business operations by leading pricing strategies, financial analyses, and company planning. Drive decision-making processes, collaborate across teams, and influence key investment dec...

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $155K *

Elevate business technology solutions by leading demand, resource capacity, and portfolio planning processes. Drive strategic alignment of technology investments with business priorities, ensuring eff...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Take ownership of patient care excellence by leading a dynamic nursing team, ensuring high-quality vascular access procedures, and fostering a supportive environment for both staff and patients in a f...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Lead the charge in shaping innovative therapeutic programs, ensuring operational excellence and regulatory compliance while fostering high-performing clinical teams to achieve exceptional patient outc...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.