Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$183K - $330K *

Champion the operational infrastructure for a groundbreaking oncology launch, optimizing analytics and field capabilities to ensure seamless execution and exceptional customer experiences in a dynamic...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Empower a dedicated team as Clinic Director, blending clinical excellence with leadership to enhance patient care and foster a collaborative environment while driving clinic growth and community engag...

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Accelerate progress at a dynamic marketing team focused on driving growth for orthodontic and pediatric practices. Collaborate with leaders to develop impactful strategies that enhance patient acquisi...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion growth by developing and executing innovative marketing strategies that enhance patient acquisition and practice performance across a network of orthodontic and pediatric practices...

Scottsbluff, NERemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Elevate clinical excellence by leading multidisciplinary care models, ensuring quality outcomes, and driving strategic initiatives. Collaborate with executive teams to enhance patient safety and organ...

3 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$177K - $278K *

Join a team that's redefining clinical operations by leading large, complex programs, ensuring compliance with regulations, and driving innovation across therapeutic areas to achieve strategic healthc...

Massachusetts, USRemote

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$269K - $350K *

Innovate regulatory strategies for rare disease development, guiding global compliance from IND through marketing application. Lead teams, drive cross-functional alignment, and engage Health Authoriti...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$182K - $275K *

Lead the design and delivery of innovative training programs for Patient Services, enhancing onboarding and continuous learning. Collaborate with cross-functional teams to ensure alignment with busine...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Empower your career by leading innovative population health strategies that enhance client outcomes and drive organizational success. Collaborate with a high-performing team to deliver data-driven sol...

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Drive operational excellence by leading manufacturing strategies, ensuring compliance, and fostering a culture of safety and continuous improvement. Collaborate across functions to enhance performance...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to patient-first care, leading a clinic with integrity and compassion. Empower your growth while fostering meaningful relationships with patients and staff in a supportive...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower patient-centered care by leading a dynamic clinic team, fostering relationships, and ensuring ethical practices. Drive clinical excellence while supporting professional growth in a collaborati...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform business insights into impactful analytics strategies, driving revenue growth and sales performance within the pharmaceutical sector. Collaborate across teams to enhance Salesforce Effective...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$154K - $231K *

Unlock potential by leading operations at a distribution center, enhancing performance, safety, and quality. Drive team development and continuous improvement while managing staffing and inventory to...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $343K *

Lead innovative medical programs for neurodevelopmental care, enhancing clinical efficiency and coordination. Drive quality and compliance, spearhead faculty training, and expand service access while...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$152K - $262K *

Lead strategic initiatives and operational functions to enhance research sustainability and efficiency. Collaborate with leadership to optimize financial performance and support the Research Enterpris...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$90K *

Empower a dedicated team to enhance senior care through community engagement, compliance, and patient growth. Lead initiatives that foster collaboration and ensure high-quality services while maintain...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$277K - $280K *

Elevate patient care by leading urgent care teams to achieve excellence, implementing strategic policies, and fostering collaboration within a dynamic medical setting. Your leadership will drive growt...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $250K *

Transform clinical trials by ensuring patient safety and scientific integrity. Collaborate with stakeholders to uphold regulatory standards and optimize study protocols, while providing expert medical...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$143K - $185K *

Unlock your potential as a strategic leader overseeing clinical operations, optimizing effectiveness, and fostering collaboration across departments. Drive initiatives, manage resources, and enhance e...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Unlock potential by leading Field Medical training and effectiveness initiatives, enhancing operational excellence through strategic planning and collaboration. Drive impactful educational programs ac...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$277K - $280K *

Grow the future of urgent care as Area Medical Director, leading teams to excel in clinical excellence and provider performance while implementing strategic policies for growth in the Richmond market...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Lead a dedicated team within urgent care to ensure clinical excellence and motivate peers. Use your experience to assess market needs, implement strategies, and drive provider performance under the gu...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $154K *

Join a team that's dedicated to enhancing patient care through effective clinic leadership. Oversee operations, manage budgets, and foster staff development while ensuring compliance and collaboration...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the charge in developing and supervising comprehensive admission procedures across various populations, ensuring efficient assessments and maintaining strong relationships with referral sources a...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.