Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$77K - $106K *

Lead the charge in delivering high-quality home health care by managing clinical operations, guiding a dedicated team, and ensuring patient-centered practices that empower independence and enhance car...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $95K *

Optimize patient care by leading a dedicated clinical team, ensuring high-quality home health services, and fostering staff development while maintaining compliance and operational excellence in a sup...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $106K *

Transform clinical operations by leading a dedicated team to deliver high-quality home care. Empower patients and clinicians alike through effective guidance, support, and coordination, ensuring excel...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $106K *

Lead a dedicated team of clinicians in delivering high-quality home health care. Oversee clinical operations, ensure compliance, and empower patients to achieve independence while fostering a supporti...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $187K *

Join a dynamic team to drive global regulatory strategies and submissions, ensuring compliance across regions. Collaborate with cross-functional teams and health authorities to facilitate timely appro...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $165K *

Drive the strategic and operational leadership of a multidisciplinary institute, enhancing neurological care through collaboration, innovation, and excellence in clinical and research initiatives. Fos...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$90K - $110K *

Contribute to the success of pharmaceutical programs by managing client relationships, overseeing daily operations, and driving performance. Collaborate cross-functionally to ensure program execution...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $155K *

Transform patient care by leading clinical services, ensuring quality standards, and fostering collaboration across departments to enhance organizational success and culture...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$164K - $213K *

Champion innovative programming solutions to enhance clinical studies, ensuring quality and compliance. Collaborate with cross-functional teams and lead programming strategies for assigned compounds...

New Jersey, USRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $125K *

Transform the nursing department's quality standards while collaborating with staff at all levels to ensure excellent patient care and employee development. Promote a culture of continuous improvement...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $190K *

Unlock potential by leading laboratory operations to ensure safe, efficient environments. Collaborate across teams to enhance research support, manage resources, and drive continuous improvement in a...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Advance your career by leading sales strategies, driving revenue growth, and cultivating key customer relationships in the healthcare and life sciences sectors. Collaborate with cross-functional teams...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$173K - $204K *

Join a team that's dedicated to enhancing clinical quality through effective GCP oversight and audits, supporting clinical studies and ensuring compliance while mentoring the next generation of QA pro...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$270K - $280K *

Lead the charge in regulatory medical writing, guiding clinical documents from draft to submission-ready. Collaborate with cross-functional teams to ensure clarity and compliance, while managing timel...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate your career by leading a dedicated team to ensure exceptional client care and compliance. Oversee staff training, coordinate services, and maintain high standards in a dynamic environment focu...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Accelerate progress at a leading medical institution by directing clinical trials, enhancing research operations, and mentoring emerging physicians in oncology. Drive innovation and strategic directio...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$73K - $112K *

Elevate surgical services by partnering with leadership to enhance operations, support staff development, and ensure compliance with standards, fostering a patient-centered environment across all peri...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$73K - $112K *

Join a team that's dedicated to enhancing surgical services through operational excellence, staff development, and quality improvement. Collaborate with leadership to ensure patient-centered care and...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$140K - $150K *

Join a team that's dedicated to advancing clinical research by managing complex studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficien...

Boston, MARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K *

Lead the charge in delivering high-quality, patient-centered care in a dynamic inpatient environment. Oversee clinical operations, guide multidisciplinary teams, and champion initiatives that enhance...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Take ownership of strategic medical leadership in Neurology, driving initiatives to enhance project outcomes. Collaborate with cross-functional teams to ensure compliance and operational excellence in...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion groundbreaking medical initiatives in neurology, guiding project teams and making strategic decisions. Leverage your expertise to ensure compliance and excellence in medical affairs while imp...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion medical affairs initiatives by leading project teams, providing expert neurology guidance, ensuring compliance, and improving patient outcomes through strategic decision-making and operationa...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Lead the charge in overseeing prior authorization operations, ensuring compliance and quality care delivery. Collaborate with clinical teams to enhance policies and workflows while managing a dedicate...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $180K *

Shape the future of patient care by leading a dynamic team in prior authorization management, ensuring compliance and quality in healthcare delivery while driving program development and operational e...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.