Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$160K - $200K *

Elevate your career by leading our Professional Services teams, driving successful software implementations, and fostering client relationships. Your strategic vision will enhance service delivery and...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$350K - $420K *

Champion exceptional patient care by leading a multidisciplinary Neurology program, ensuring clinical excellence and collaboration across the Great Lakes Region while fostering physician development a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Take ownership of clinic operations, ensuring high-quality care and compliance. Lead a dedicated team, manage budgets, and foster community partnerships to enhance patient experiences in a supportive...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Champion high-quality care as you lead daily operations, ensuring compliance and strategic alignment. Shape patient experiences and foster a supportive team culture while overseeing budget management...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$118K - $169K *

Champion the delivery of exceptional nursing care by overseeing operations, staff management, and quality assurance in a skilled nursing facility. Drive improvements in patient outcomes while fosterin...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Unlock potential by leading a clinic with entrepreneurial spirit, driving growth, and building a high-performing team. Collaborate on innovative programs and take ownership of your clinic's success wh...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $100K *

Join a dynamic team as you lead and inspire a clinic dedicated to enhancing patient care and community well-being through orthopedic expertise and effective leadership...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $100K *

Shape the future of patient care by leading a dynamic team in outpatient physical therapy, enhancing company culture, and driving community engagement through exceptional orthopedic services and effec...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by leading a dynamic research team, ensuring compliance, and driving successful clinical trials from initiation to closeout while fostering collaboration with sponsors and staff...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $130K *

Lead operational excellence and financial performance at our site, driving team development and compliance with clinical standards while ensuring optimal staffing and productivity for sustained growth...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion operational excellence by overseeing oncology site management, ensuring compliance, driving financial performance, and leading team development to support high-quality clinical trials for imp...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$232K - $290K *

Optimize revenue generation by leading Sales and Revenue Operations, driving performance across customer-facing teams, and fostering a culture of excellence through strategic initiatives and cross-fun...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Champion operational excellence in AI server repair, leading strategic initiatives, driving continuous improvement, and ensuring compliance while managing P&L and fostering cross-functional collaborat...

Today

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Drive strategic leadership in dental operations, enhance team performance, and improve patient care access across multiple locations while ensuring operational efficiency and compliance...

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$83K - $99K *

Advance patient care by leading innovative therapy programs in a senior living community, collaborating with interdisciplinary teams to enhance rehabilitation services and support overall wellness for...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $110K *

Advance client health by coordinating comprehensive medical care, ensuring compliance with health regulations, and fostering partnerships with healthcare providers. Lead a dedicated team to maintain h...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$207K - $310K *

Champion the global incentive compensation operations, leading a team to ensure accurate payouts and compliance. Collaborate across departments to drive process improvements and leverage technology fo...

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$207K - $310K *

Drive global incentive compensation operations, ensuring accurate payouts and compliance. Collaborate with cross-functional teams to enhance processes and implement automation, while leading a team fo...

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$207K - $310K *

Lead a global team to ensure accurate incentive compensation payouts, collaborating across departments to drive process improvements and AI adoption while enhancing the seller experience and complianc...

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$207K - $310K *

Manage a global team to ensure accurate incentive payouts, drive process improvements, and collaborate across departments. Lead the implementation of compensation plans while enhancing seller experien...

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$207K - $310K *

Drive the future of incentive compensation operations by leading a global team to ensure accurate payouts, enhance processes, and collaborate across departments to optimize performance and compliance...

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$184K - $276K *

Join us to lead a global team in optimizing incentive compensation operations, ensuring accurate payouts and compliance. Collaborate across departments to drive process improvements and enhance the se...

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Empower clinical excellence as you oversee operations, enhance patient care, and lead a dedicated team in a dynamic surgical environment. Drive efficiency, fiscal accountability, and staff development...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in enhancing patient care by overseeing daily operations, implementing process improvements, and fostering a collaborative environment to ensure optimal efficiency and outcomes in an o...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Tackle the challenge of leading clinical operations in an ambulatory surgical center. Oversee staff development, ensure quality assurance, and drive program growth while fostering a collaborative envi...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.