Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$127K - $155K *
Elevate participant engagement by implementing strategic retention initiatives, analyzing clinical trial data, and collaborating with cross-functional teams to ensure data integrity and minimize dropo...
Yesterday
Senior Director, Research Strategy and Operations (Core Team Leader)
$192K - $264K *
Oversee the product development lifecycle, leading cross-functional teams to ensure timely and compliant launch of complex diagnostic products, while driving strategic decisions and resolving interdep...
Yesterday
Associate Director, Global Program Management (Oncology)
$139K - $232K *
Champion drug development by leading cross-functional teams to optimize project strategies, manage risks, and ensure timely delivery of critical milestones in a complex life sciences environment...
1 week ago
Director of ABA Clinical Services
$100K - $110K *
Empower clinical teams to deliver high-quality, evidence-based ABA therapy. Lead and mentor professionals while collaborating across functions to enhance client care and support growth in a compassion...
Today
Director of ABA Clinical Services
$100K - $110K *
Empower clinical teams to deliver high-quality, evidence-based ABA therapy. Lead and mentor professionals while collaborating across functions to enhance client care and support growth in a compassion...
3 days ago
$210K - $250K *
Champion patient-centered care by leading a clinical team to enhance quality, ensure effective provider support, and drive strategic healthcare initiatives. Focus on mentoring and implementing value-b...
Reposted 4 weeks ago
Senior Medical Director, Clinical Development, MASH
$333K - $450K *
Lead the charge in innovative clinical programs, shaping strategies and executing trials from first-in-human to registration, while ensuring patient safety and compliance in a dynamic regulatory envir...
1 week ago
Director - Operational Excellence
$125K - $150K *
Join a dynamic team to drive operational excellence across multiple manufacturing sites, fostering continuous improvement strategies and Lean practices to enhance safety, quality, delivery, and produc...
Reposted 1 week ago
Director - Operational Excellence
$130K - $160K *
Drive operational excellence by implementing a unified continuous improvement system across sites, enhancing productivity, and fostering a culture of accountability and innovation while collaborating...
Reposted 1 week ago
$95K - $115K *
Transform clinical quality by supporting training initiatives, monitoring clinician performance, and ensuring compliance with quality standards for successful operational processes and clinician suppo...
Reposted yesterday
Director of Health Information Management & Administration
$100K - $120K *
Transform health information management by leading end-to-end processes, ensuring compliance, and optimizing workflows. Collaborate across departments to enhance operational performance and support or...
Yesterday
Director - Clinical Research Physician, GPS Medical - Infectious Disease
$201K - $360K *
Shape the future of patient safety by leading pharmacovigilance efforts, ensuring compliance, and fostering collaboration across teams to enhance drug development and safety oversight throughout produ...
Today
Executive Director, Global Medical Neuroscience, Schizophrenia Medical Product Lead
$254K - $308K *
Shape the future of Global Medical Psychiatry by leading innovative strategies for Schizophrenia. Oversee medical activities, foster key partnerships, and drive the execution of groundbreaking project...
3 weeks ago
$303K - $370K *
Unlock your potential as you lead comprehensive care assessments and coordinate individualized plans, ensuring effective participant care in a mission-driven environment focused on value-based relatio...
1 week ago
$170K - $190K *
Lead the charge in optimizing and scaling student financial operations, enhancing processes through strategic partnerships and technology. Drive continuous improvement to ensure efficiency, compliance...
Reposted 4 weeks ago
Senior Clinical Trial Associate
$100K - $120K *
Transform clinical trial operations by supporting planning, execution, and closeout activities. Collaborate with cross-functional teams, ensuring timely communication and quality oversight while takin...
Reposted 6 days ago
$100K - $120K *
Drive excellence in patient care by leading clinical operations, enhancing quality standards, and fostering team development. Collaborate on strategic initiatives to improve safety, efficiency, and pa...
1 week ago
$80K - $95K *
Support our EMR and clinical applications projects by leading cross-functional teams, managing timelines, and ensuring successful implementation. Collaborate with stakeholders to enhance workflows and...
2 weeks ago
Senior Director, Translational Medicine
$252K - $304K *
Drive innovative biomarker research and lead cross-functional teams to enhance clinical programs. Contribute strategic insights and champion novel approaches in translational medicine, ensuring impact...
3 weeks ago
Urgent Care Physician with Medical Directorship
$380K *
Elevate patient care as a Staff Physician in a thriving urgent care setting, managing mid-level providers and delivering comprehensive treatment with opportunities for advancement in medical leadershi...
Reposted yesterday
Director of Patient Care Services
$100K - $120K *
Pioneer a transformative approach to patient care services by overseeing dental education operations, managing faculty-student interactions, and ensuring high standards in clinic efficiency while adhe...
Reposted 2 weeks ago
$188K - $263K *
Empower organizational growth by serving as a strategic HR partner, blending business acumen with HR expertise to enhance team effectiveness, drive change, and support leaders in a dynamic biotech env...
Today
Medical Director, Neurodegenerative & Movement Disorders, Neuroscience, Global Patient Safety
$210K - $250K *
Transform the safety landscape by supporting comprehensive surveillance of neuroscience products, ensuring compliance with pharmacovigilance regulations, and contributing to critical safety documentat...
2 weeks ago
$80K - $95K *
Empower a dedicated team to enhance resident health and wellness while ensuring compliance with regulations. Lead daily healthcare operations, develop personalized care plans, and foster a culture of...
3 days ago
Exec Dir, ACMO Clinical Services
$180K - $220K *
Oversee strategic physician leadership for clinical documentation initiatives, driving performance improvement and operational excellence while fostering collaboration across healthcare teams to enhan...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.