Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$80K - $95K *

Join a team that's dedicated to delivering compassionate care while overseeing daily operations, ensuring staff efficiency, and fostering a risk-free environment for patients in a dynamic healthcare s...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Drive clinical trial success by managing operations, monitoring, and site relationships for diverse studies. Collaborate cross-functionally to ensure compliance, data integrity, and high-quality outco...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $213K *

Shape the future of virtual care by driving strategic initiatives and enhancing program performance. Collaborate with cross-functional teams to ensure operational efficiency and lead the development o...

Tempe, AZRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $213K *

Elevate the Virtual Care program by driving strategic initiatives, enhancing performance, and collaborating across teams. Lead operational efficiency and program management while supporting the growth...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $236K *

Lead the charge in driving strategic initiatives for a Virtual Care program, enhancing operational efficiency and performance through cross-functional collaboration and effective program management...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $236K *

Transform the Virtual Care program by driving strategy and execution of key projects. Collaborate cross-functionally to enhance operational efficiency and improve performance metrics while leading a t...

New York, NYRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive enterprise clinical performance initiatives, translating executive priorities into actionable plans. Lead cross-functional teams, establish governance structures, and ensure accountability for s...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$222K - $371K *

Join a team that's dedicated to transforming cancer care through innovative clinical development. As a key medical expert, you'll oversee study design, ensure patient safety, and collaborate with cros...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's dedicated to enhancing client onboarding and delivery of innovative solutions. Lead cross-functional efforts to ensure successful integration and adoption of products while driving...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Grow and lead nursing services by planning, organizing, and directing staff to ensure optimal resident care while maintaining compliance with regulations and fostering a supportive environment for pro...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $108K *

Advance your career by leading a dedicated nursing team to enhance resident care quality. Oversee daily operations, ensure compliance, and drive performance in a mission-driven environment focused on...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K *

Transform healthcare delivery by leading a dedicated team, ensuring quality services and compliance while promoting individual well-being and safety. Drive improvements in medical support and staff tr...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Join a team that's dedicated to delivering exceptional healthcare services by overseeing and managing nursing staff, ensuring quality care, compliance with regulations, and promoting the well-being of...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Lead the charge in advancing clinical research by managing trials, ensuring compliance, and driving innovation within a multidisciplinary team to enhance patient care and safety...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $215K *

Shape the future of quality engineering by leading strategic initiatives across diverse technology portfolios. Drive team performance, enhance delivery quality, and embed innovative practices to ensur...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$156K - $215K *

Elevate quality engineering practices by leading teams to enhance delivery, automation, and continuous improvement across a diverse technology portfolio, ensuring robust software development and produ...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Deliver comprehensive quality management solutions across GLP, GCP, and GMP domains, ensuring audit readiness, vendor compliance, and regulatory adherence, while fostering collaboration between R&D, C...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive operational excellence by leveraging analytics to optimize workforce strategy, enhance patient experiences, and support growth. Collaborate across teams to transform data into actionable insight...

Today

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Join a dynamic team to drive operational excellence through data-driven strategies. Lead workforce planning, enhance performance metrics, and collaborate across functions to optimize patient services...

Today

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Unlock your potential as a strategic leader in operations analytics, driving workforce strategy and performance improvements across contact center and pharmacy operations. Collaborate with cross-funct...

Today

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Transform data into actionable insights as you lead workforce strategy and analytics. Collaborate across teams to optimize operations, enhance patient experiences, and drive performance improvements i...

Today

  •   8 - 10 years exp.  •   Healthcare

$156K - $215K *

Drive quality engineering excellence by leading teams to enhance testing, automation, and continuous improvement across diverse technology portfolios, ensuring robust delivery and production stability...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$247K - $334K *

Transform the safety profile of products by leading strategic assessments, guiding clinical teams, and ensuring compliance with regulatory standards throughout the product lifecycle. Collaborate acros...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform the landscape of ophthalmology research by leading operational strategies, ensuring regulatory compliance, and guiding a dedicated team. Drive high-quality, impactful human subject research...

1 month ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $105K *

Drive excellence in home health services by leading an interdisciplinary team, ensuring high-quality, client-centered care while optimizing operational efficiency and compliance with regulatory standa...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.