Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$126K - $200K *

Transform the Safety Assessment department by leading GLP compliance, developing strategic plans, and ensuring operational excellence while mentoring staff and engaging with clients to meet their need...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Elevate operational excellence by partnering with leadership to drive strategic initiatives, enhance productivity, and foster a culture of continuous improvement. Lead change management and communicat...

Edmonton, ABIn-Person

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Join a team that's dedicated to managing and enhancing clinical programs, ensuring quality patient care through effective leadership and collaboration with multidisciplinary teams to drive positive he...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$196K - $269K *

Champion innovative strategies in incentive compensation and sales planning, driving performance and customer engagement across diverse teams. Collaborate with leadership to optimize field execution a...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$196K - $269K *

Empower commercial success by leading incentive compensation and sales planning strategies. Collaborate with cross-functional teams to optimize field execution, drive performance, and enhance customer...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$91K - $110K *

Join a team that's dedicated to enhancing clinical nursing services and ensuring quality care outcomes. This leadership role involves coordinating resident care, managing staff performance, and suppor...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Empower clinical excellence by leading a state-of-the-art chiropractic practice, driving patient care, and cultivating a dynamic team. Bring your entrepreneurial spirit to shape the clinic’s future wh...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Lead the daily operations of a medical group, ensuring productivity and efficiency across various departments. Collaborate with staff and physicians to enhance patient services and implement effective...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$186K - $233K *

Shape the future of clinical supply planning by leading global strategies, ensuring accurate demand forecasting, and driving process improvements for clinical programs. Collaborate with cross-function...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of behavioral health by leading strategic marketing and intake services. Drive growth, mentor teams, and enhance community care through innovative business development initiatives acr...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $170K *

Lead clinical operations for a transformative pretrial supervision program, ensuring adherence to best practices and enhancing service delivery through innovative training and quality assurance initia...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$140K - $170K *

Elevate clinical practice within the Supervised Release Program by ensuring adherence to best practices, enhancing service delivery, and fostering innovation in participant care through comprehensive...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$164K - $205K *

Elevate clinical operations by leading complex trials, ensuring compliance, and driving cross-functional collaboration. Utilize your expertise to manage timelines, budgets, and stakeholder communicati...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Transform strategic positioning and messaging for AI in healthcare, driving impactful go-to-market initiatives. Collaborate across teams to enhance value narratives, ensuring successful launches and a...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in enhancing quality improvement initiatives, ensuring compliance and operational excellence across behavioral health services. Collaborate with leadership to foster a culture of accou...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Champion timely medical decisions in post-acute care, ensuring consistent clinical reviews and necessity determinations. Collaborate with medical staff to enhance patient outcomes while supporting ope...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Join a team that's committed to delivering high-quality post-acute care. Support clinical operations by ensuring timely medical decisions and effective communication between providers and members, enh...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Join our team as a Clinical Operations Associate Medical Director, enhancing post-acute care management through timely clinical reviews and medical necessity determinations while working flexibly in a...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Innovate within Post Acute Care to enhance clinical decision-making, ensuring timely medical reviews. Collaborate with medical teams, maintaining policy consistency and improving patient outcomes in a...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Champion clinical excellence by ensuring timely medical reviews and decisions for post-acute care. Collaborate with medical management staff and providers to enhance patient care, utilizing expert kno...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Lead the charge in optimizing post-acute care by ensuring timely clinical decision-making. Collaborate with medical teams to define medical necessity while working flexibly in a supportive virtual env...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Lead the charge in clinical management, ensuring timely decisions for post-acute care services, while supporting the medical management team to enhance outcomes and utilization across various specialt...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Grow your career with a team focused on enhancing post-acute care through effective clinical management. Lead medical decision-making, ensuring high standards of patient care while collaborating with...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Advance your career as a key player in medical management, ensuring timely clinical decision-making and supporting providers in post-acute care settings. Enjoy virtual flexibility while making an impa...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $307K *

Elevate medical management by ensuring timely and accurate clinical case reviews, collaborating with peers for medical necessity assessments, and adhering to established policies to drive efficient ou...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.